Zobrazeno 1 - 10
of 106
pro vyhledávání: '"Virology/Mechanisms of Resistance and Susceptibility, including Host Genetics"'
Publikováno v:
PLoS ONE
Background We have developed multiple stable cell lines containing subgenomic HCV RNA that are resistant to treatment with interferon alpha (IFN-α. Characterization of these IFN-α resistant replicon cells showed defects in the phosphorylation and n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2cf2d5f95e223770d090ef6e40e15151
https://pubmed.ncbi.nlm.nih.gov/20949125
https://pubmed.ncbi.nlm.nih.gov/20949125
Autor:
Hien, TT, Boni, MF, Bryant, JE, Ngan, TT, Wolbers, M, Nguyen, TD, Truong, NT, Dung, NT, Ha, DQ, Hien, VM, Thanh, TT, Nhu, LNT, Uyen, LTT, Nhien, PT, Chinh, NT, Chau, NV, Farrar, J, Van Doorn, HR, Ha, DOQ, Nhu, LENT, Uyen, LETT
Publikováno v:
PLoS Medicine, Vol 7, Iss 5, p e1000277 (2010)
PLoS Medicine
PLoS Medicine
Rogier van Doorn and colleagues analyze the initial outbreak, attempts at containment, and establishment of community transmission of pandemic H1N1 influenza in Ho Chi Minh City, Vietnam.
Background To date, little is known about the initial spr
Background To date, little is known about the initial spr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be49d15e33441d43fc10c439b2c8e616
https://ora.ox.ac.uk/objects/uuid:79a3707c-636c-49ae-a5c1-d4d55da479c3
https://ora.ox.ac.uk/objects/uuid:79a3707c-636c-49ae-a5c1-d4d55da479c3
Autor:
Trinh Thi Minh Lien, Pham Thi Khuong, Jeremy Farrar, Annette Fox, Peter Horby, Tran Thi Hai Ninh, Le Nguyen Minh Hoa, Marcel Wolbers, Walter R. J. Taylor, Heiman F. L. Wertheim, Nguyen Thi Nam Lien, Cameron P. Simmons, Nguyen Vu Trung, Nguyen Van Kinh, Nguyen Duc Hien
Publikováno v:
PLoS Neglected Tropical Diseases
PLoS Neglected Tropical Diseases, Vol 5, Iss 3, p e967 (2011)
PLoS Neglected Tropical Diseases, Vol 5, Iss 3, p e967 (2011)
Background The relationships between the infecting dengue serotype, primary and secondary infection, viremia and dengue severity remain unclear. This cross-sectional study examined these interactions in adult patients hospitalized with dengue in Ha N
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ce9906d4c6d892e8ab40d25de7736ab
http://europepmc.org/articles/PMC3046970
http://europepmc.org/articles/PMC3046970
Autor:
Angela M. Mexas, Megan K. Liszewski, Erin H. Graf, Una O'Doherty, Michele Di Mascio, Stephen A. Migueles, Farida Shaheen, Mark Connors, Jianqing J. Yu
Publikováno v:
PLoS Pathogens, Vol 7, Iss 2, p e1001300 (2011)
PLoS Pathogens
PLoS Pathogens
Elite suppressors (ES) are a rare population of HIV-infected individuals that are capable of naturally controlling the infection without the use of highly active anti-retroviral therapy (HAART). Patients on HAART often achieve viral control to simila
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1139db4acaf6f3ff0eaaa7472e5e5dad
http://europepmc.org/articles/PMC3044690?pdf=render
http://europepmc.org/articles/PMC3044690?pdf=render
Autor:
Charles M. Rice, Zhigang Yi, Cindy Nürnberger, Lindsey Sperzel, Peter J. Bredenbeek, Margaret R. MacDonald, Cristina Stoyanov, Lok Man J. Law, Kirk J. Lubick, Sonja M. Best, Zhenghong Yuan
Publikováno v:
PLoS Pathogens, 7(1)
PLoS Pathogens, Vol 7, Iss 1, p e1001255 (2011)
PLoS Pathogens
PLoS Pathogens, Vol 7, Iss 1, p e1001255 (2011)
PLoS Pathogens
Viruses in the Flavivirus genus of the Flaviviridae family are arthropod-transmitted and contribute to staggering numbers of human infections and significant deaths annually across the globe. To identify cellular factors with antiviral activity again
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f49682f2ad8806230f4538a435caa88
http://hdl.handle.net/1887/109123
http://hdl.handle.net/1887/109123
Autor:
P. Richard Harrigan, Andrew Rambaut, Bruce E Taillon, David Robertson, John A. C. Archer, Marilyn Lewis
Publikováno v:
Archer, J, Rambaut, A, Taillon, B E, Harrigan, P R, Lewis, M & Robertson, D L 2010, ' The Evolutionary Analysis of Emerging Low Frequency HIV-1 CXCR4 Using Variants through Time-An Ultra-Deep Approach ', PLoS Computational Biology, vol. 6, no. 12, e1001022, pp.-. https://doi.org/10.1371/journal.pcbi.1001022
PLoS Computational Biology, Vol 6, Iss 12, p e1001022 (2010)
PLoS Computational Biology
PLoS Computational Biology, Vol 6, Iss 12, p e1001022 (2010)
PLoS Computational Biology
Large-scale parallel pyrosequencing produces unprecedented quantities of sequence data. However, when generated from viral populations current mapping software is inadequate for dealing with the high levels of variation present, resulting in the pote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14cf781c4d59bf1b6ed0054933ff576e
https://eprints.gla.ac.uk/152140/1/152140.pdf
https://eprints.gla.ac.uk/152140/1/152140.pdf
Autor:
Saludes, Verónica, Bracho, Maria Alma, Valero, Oliver, Ardèvol, Mercè, Planas, Ramón, González-Candelas, Fernando, Ausina, Vicente, Martró, Elisa, Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia
Publikováno v:
PLoS ONE, Vol 5, Iss 11, p e14132 (2010)
PLoS ONE
PLoS ONE
Background Current treatment of chronic hepatitis C virus (HCV) infection has limited efficacy −especially among genotype 1 infected patients−, is costly, and involves severe side effects. Thus, predicting non-response is of major interest for bo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7410f69cc58c0580623c35161843cd5
http://europepmc.org/articles/PMC2994723?pdf=render
http://europepmc.org/articles/PMC2994723?pdf=render
Autor:
Tonau Nakai, Tatsuaki Tsuruyama, Takuro Nakamura, Guang Jin, Takuya Hiratsuka, Kenichi Yoshikawa
Publikováno v:
PLoS ONE
PLoS ONE, Vol 5, Iss 11, p e13841 (2010)
PLoS ONE, Vol 5, Iss 11, p e13841 (2010)
Although there have been a few reports that the HIV-1 genome can be selectively integrated into the genomic DNA of cultured host cell, the biochemistry of integration selectivity has not been fully understood. We modified the in vitro integration rea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::392e79941d9f54c66f52e2b4be020523
http://europepmc.org/articles/PMC2973958
http://europepmc.org/articles/PMC2973958
Autor:
Laura I. Levi, Malia J. McPherson, Jamie J. Arnold, Stéphanie Beaucourt, Bruno Baron, Marco Vignuzzi, Nina F. Gnädig
Publikováno v:
PLoS Pathogens
PLoS Pathogens, 2010, 6 (10), pp.e1001163. ⟨10.1371/journal.ppat.1001163⟩
PLoS Pathogens, Public Library of Science, 2010, 6 (10), pp.e1001163. ⟨10.1371/journal.ppat.1001163⟩
PLoS Pathogens, Vol 6, Iss 10, p e1001163 (2010)
PLoS Pathogens, 2010, 6 (10), pp.e1001163. ⟨10.1371/journal.ppat.1001163⟩
PLoS Pathogens, Public Library of Science, 2010, 6 (10), pp.e1001163. ⟨10.1371/journal.ppat.1001163⟩
PLoS Pathogens, Vol 6, Iss 10, p e1001163 (2010)
In a screen for RNA mutagen resistance, we isolated a high fidelity RNA dependent RNA polymerase (RdRp) variant of Coxsackie virus B3 (CVB3). Curiously, this variant A372V is also resistant to amiloride. We hypothesize that amiloride has a previously
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c81d1d931e56d1bfdfa6f17a6484cf5
Autor:
Hélder A. M. Pedro, Lior Pachter, Adam P. Arkin, Stephanie M. Willerth, David V. Schaffer, Laurent Humeau
Publikováno v:
PloS one, vol 5, iss 10
PLoS ONE, Vol 5, Iss 10, p e13564 (2010)
PLoS ONE
PLoS ONE, Vol 5, Iss 10, p e13564 (2010)
PLoS ONE
Background: With an estimated 38 million people worldwide currently infected with human immunodeficiency virus (HIV), and an additional 4.1 million people becoming infected each year, it is important to understand how this virus mutates and develops
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a58452a6cb53adc4657d313d5673afc0
https://escholarship.org/uc/item/0q1620ff
https://escholarship.org/uc/item/0q1620ff