Zobrazeno 1 - 10
of 139
pro vyhledávání: '"Virology/Immune Evasion"'
Publikováno v:
PLoS ONE
Background We have developed multiple stable cell lines containing subgenomic HCV RNA that are resistant to treatment with interferon alpha (IFN-α. Characterization of these IFN-α resistant replicon cells showed defects in the phosphorylation and n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2cf2d5f95e223770d090ef6e40e15151
https://pubmed.ncbi.nlm.nih.gov/20949125
https://pubmed.ncbi.nlm.nih.gov/20949125
Autor:
Hester Boersma, Emmanuel J. H. J. Wiertz, Rob C. Hoeben, Dirk W. van Bekkum, Shoshan Knaän-Shanzer, Ietje van der Velde-van Dijke, Antoine A.F. de Vries, Anabel S de la Garza-Rodea, Marieke C. Verweij
Publikováno v:
PLoS ONE
PLoS ONE, 6(1), e14493
PLoS ONE, Vol 6, Iss 1, p e14493 (2011)
PLoS ONE, 6(1)
PLoS ONE, 6(1), e14493
PLoS ONE, Vol 6, Iss 1, p e14493 (2011)
PLoS ONE, 6(1)
BackgroundMesenchymal stem cells (MSCs) are multipotent cells residing in the connective tissue of many organs and holding great potential for tissue repair. In culture, human MSCs (hMSCs) are capable of extensive proliferation without showing chromo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2e4f50004e9d939ec9b674a73b8aa8b
https://hdl.handle.net/1887/119029
https://hdl.handle.net/1887/119029
Autor:
Srinika R. F. Ranasinghe, Holger B. Kramer, Cynthia Wright, Benedikt M. Kessler, Katalin di Gleria, Yonghong Zhang, Geraldine M. Gillespie, Marie-Eve Blais, Abigail Culshaw, Tica Pichulik, Alison Simmons, Sarah L. Rowland-Jones, Andrew J. McMichael, Tao Dong
Publikováno v:
PLoS Pathogens
PLoS Pathogens, Vol 7, Iss 5, p e1001341 (2011)
PLoS Pathogens, Vol 7, Iss 5, p e1001341 (2011)
A major challenge to developing a successful HIV vaccine is the vast diversity of viral sequences, yet it is generally assumed that an epitope conserved between different strains will be recognised by responding T-cells. We examined whether an invari
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc4e056146e15ee78a2f56044e422932
http://ora.ox.ac.uk/objects/uuid:02031ac6-2927-40ed-bf60-a90b5c2f1dc8
http://ora.ox.ac.uk/objects/uuid:02031ac6-2927-40ed-bf60-a90b5c2f1dc8
Autor:
Elaine Bennett, Deborah Howarth, David J. Hughes, Jeffery T. Sample, R. Papoula-Pereira, Brian F. Flanagan, James P. Stewart, Joanne A. Cummerson, Gail Leeming, Anja Kipar
Publikováno v:
PLoS Pathogens, Vol 7, Iss 3, p e1001321 (2011)
PLoS Pathogens
PLOS PATHOGENS
PLoS Pathogens
PLOS PATHOGENS
Murine γ-herpesvirus 68 (MHV-68) infection of Mus musculus-derived strains of mice is an attractive model of γ-herpesvirus infection. Surprisingly, however, ablation of expression of MHV-68 M3, a secreted protein with broad chemokine-binding proper
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4d937acd08139a9722aafa267d0e1f1
https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21445235/pdf/?tool=EBI
https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21445235/pdf/?tool=EBI
Autor:
Galit Alter, R. Paul Johnson, Arnaud D. Colantonio, David H. O’Connor, R. Keith Reeves, Mary Carrington, Marcus Altfeld, Benjamin N. Bimber, William J. Neidermyer, David T. Evans
Publikováno v:
PLoS Pathogens, Vol 7, Iss 3, p e1001316 (2011)
PLoS Pathogens
PLoS Pathogens
Molecular interactions between killer immunoglobulin-like receptors (KIRs) and their MHC class I ligands play a central role in the regulation of natural killer (NK) cell responses to viral pathogens and tumors. Here we identify Mamu-A1*00201 (Mamu-A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1769ac512c803503ccc8ab8d6fdc2d9f
https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21423672/?tool=EBI
https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21423672/?tool=EBI
Autor:
M. Steven Oberste, Stefanie A. Morosky, Tianyi Wang, Carolyn B. Coyne, Elizabeth Delorme-Axford, Naomi Dybdahl-Sissoko, Amitava Mukherjee
Publikováno v:
PLoS Pathogens, Vol 7, Iss 3, p e1001311 (2011)
PLoS Pathogens
PLoS Pathogens
The host innate immune response to viral infections often involves the activation of parallel pattern recognition receptor (PRR) pathways that converge on the induction of type I interferons (IFNs). Several viruses have evolved sophisticated mechanis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::596d49a28ad78afaa4ef32b578e50b37
https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21436888/pdf/?tool=EBI
https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21436888/pdf/?tool=EBI
Autor:
Paola Miyazato, Yorifumi Satou, Jun-ichirou Yasunaga, Tiejun Zhao, Kei Shimizu, Naganari Ohkura, Patrick L. Green, Mika Yoshida, Masao Matsuoka, Koichi Ohshima, Shimon Sakaguchi, Ken Takai, Masahiro Ono, Tomoyuki Yamaguchi
Publikováno v:
PLoS Pathogens, Vol 7, Iss 2, p e1001274 (2011)
PLoS Pathogens
PLoS Pathogens
Human T-cell leukemia virus type 1 (HTLV-1) is the causal agent of a neoplastic disease of CD4+ T cells, adult T-cell leukemia (ATL), and inflammatory diseases including HTLV-1 associated myelopathy/tropical spastic paraparesis, dermatitis, and infla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b83490f0152d901fb9524de3eb3855cc
http://hdl.handle.net/2433/137213
http://hdl.handle.net/2433/137213
Autor:
Ramtin Rahbar, Bing Sun, Michael C. W. Chan, J. S. Malik Peiris, Danlin Jia, Darren P. Baker, Eleanor N. Fish, Renee W. Y. Chan, Ben Xuhao Wang, Suki M. Y. Lee, John M. Nicholls
Publikováno v:
PLoS ONE, Vol 5, Iss 11, p e13927 (2010)
PLoS ONE
PLoS ONE
Type I interferons (IFNs) function as the first line of defense against viral infections by modulating cell growth, establishing an antiviral state and influencing the activation of various immune cells. Viruses such as influenza have developed mecha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fdd12c7826998d2f534de329387d692b
http://europepmc.org/articles/PMC2978095?pdf=render
http://europepmc.org/articles/PMC2978095?pdf=render
Autor:
Jack R. Bennink, Pere Puigbò, Suman R. Das, Scott E. Hensley, Darrell E. Hurt, Jonathan W. Yewdell
Publikováno v:
PLoS Pathogens
PLoS Pathogens, Vol 6, Iss 11, p e1001211 (2010)
PLoS Pathogens, Vol 6, Iss 11, p e1001211 (2010)
Antigenic drift in the influenza A virus hemagglutinin (HA) is responsible for seasonal reformulation of influenza vaccines. Here, we address an important and largely overlooked issue in antigenic drift: how does the number and location of glycosylat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2121d29240168e92f8bf87b98c90c446
http://europepmc.org/articles/PMC2991263
http://europepmc.org/articles/PMC2991263
Publikováno v:
PLoS Pathogens, Vol 6, Iss 10, p e1001151 (2010)
PLoS Pathogens
PLoS Pathogens
Viruses are known to employ different strategies to manipulate the major histocompatibility (MHC) class I antigen presentation pathway to avoid recognition of the infected host cell by the immune system. However, viral control of antigen presentation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::346efddc9ce97b04c9933dfcfd0ee4cb
http://europepmc.org/articles/PMC2954899?pdf=render
http://europepmc.org/articles/PMC2954899?pdf=render