Výsledky vyhledávání - "Virology/Host Invasion and Cell Entry"

Comment on 'Large Bottleneck Size in Cauliflower Mosaic Virus Populations during Host Plant Colonization' by Monsion et al. (2008)

Autor: Yannis Michalakis, Gaël Thébaud

Publikováno v: PLoS Pathogens
PLoS Pathogens, Public Library of Science, 2016, 12 (4), pp.e1005512. ⟨10.1371/journal.ppat.1005512⟩
PLoS Pathogens, 2016, 12 (4), pp.e1005512. ⟨10.1371/journal.ppat.1005512⟩
PLoS Pathogens, Vol 12, Iss 4, p e1005512 (2016)
Plos Pathogens 4 (12), e1005512. (2016)

The effective size of populations (Ne) determines whether selection or genetic drift is the predominant force shaping their genetic structure and evolution. Despite their high mutation rate and rapid evolution, this parameter is poorly documented exp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a2b577b17c3b17af3eda218b980f2d7
https://hal.umontpellier.fr/hal-02003715/file/journal.ppat.1005512.PDF

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Teaching New Tricks to an Old Foe: Murinizing Hepatitis C Virus

Autor: Gisa Gerold, Alexander Ploss, Charles M. Rice

Publikováno v: PLoS Pathogens

Hepatitis C virus (HCV) naturally infects only humans and chimpanzees. The determinants responsible for this narrow species tropism are not well defined. Virus cell entry involves human scavenger receptor class B type I (SR-BI), CD81, claudin-1 and o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86cc936fc44234140117e3d86f404acd
https://doi.org/10.1002/hep.24045

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Epstein-Barr Virus Infection of Polarized Epithelial Cells via the Basolateral Surface by Memory B Cell-Mediated Transfer Infection

Autor: Martin Rowe, Claire Shannon-Lowe

Publikováno v: PLoS Pathogens
PLoS Pathogens, Vol 7, Iss 5, p e1001338 (2011)

Epstein Barr virus (EBV) exhibits a distinct tropism for both B cells and epithelial cells. The virus persists as a latent infection of memory B cells in healthy individuals, but a role for infection of normal epithelial is also likely. Infection of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad9aed03574b64d2131791c9927ecfee
http://europepmc.org/articles/PMC3088705

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Charge-Surrounded Pockets and Electrostatic Interactions with Small Ions Modulate the Activity of Retroviral Fusion Proteins

Autor: Daan M. F. van Aalten, David W. Brighty, Alexander W. Schüttelkopf, Daniel Lamb

Publikováno v: PLoS Pathogens
PLoS Pathogens, Vol 7, Iss 2, p e1001268 (2011)

Refolding of viral class-1 membrane fusion proteins from a native state to a trimer-of-hairpins structure promotes entry of viruses into cells. Here we present the structure of the bovine leukaemia virus transmembrane glycoprotein (TM) and identify a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c12aa872d5cea65dddd53b06f2667bf9

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Dengue Virus Ensures its Fusion in Late Endosomes Using Compartment-Specific Lipids

Autor: Sergei Pourmal, Leonid V. Chernomordik, Elena Zaitseva, Kamran Melikov, Sung-Tae Yang

Publikováno v: PLoS Pathogens
PLoS Pathogens, Vol 6, Iss 10, p e1001131 (2010)

Many enveloped viruses invade cells via endocytosis and use different environmental factors as triggers for virus-endosome fusion that delivers viral genome into cytosol. Intriguingly, dengue virus (DEN), the most prevalent mosquito-borne virus that

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b6188c4436ff5661fffd0739b4b40c0

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DC-SIGN Mediated Sphingomyelinase-Activation and Ceramide Generation Is Essential for Enhancement of Viral Uptake in Dendritic Cells

Autor: Avota, Elita, Gulbins, Erich, Schneider-Schaulies, Sibylle

Publikováno v: PLoS Pathogens
PLoS Pathogens, Vol 7, Iss 2, p e1001290 (2011)

As pattern recognition receptor on dendritic cells (DCs), DC-SIGN binds carbohydrate structures on its pathogen ligands and essentially determines host pathogen interactions because it both skews T cell responses and enhances pathogen uptake for cis

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::b20588829e83e27b4c869f226b3118e1
http://europepmc.org/articles/PMC3040670

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Imaging single retrovirus entry through alternative receptor isoforms and intermediates of virus-endosome fusion

Autor: Gregory B. Melikyan, Erik W. Martin, Naveen K. Jha, John Naughton, John A. T. Young, Olga Latinovic, Kosuke Miyauchi, Gennadiy Novitskiy, Mariana Marin

Publikováno v: PLoS Pathogens, Vol 7, Iss 1, p e1001260 (2011)
PLoS Pathogens

A large group of viruses rely on low pH to activate their fusion proteins that merge the viral envelope with an endosomal membrane, releasing the viral nucleocapsid. A critical barrier to understanding these events has been the lack of approaches to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c62951707dafb2f90aea39a715617a9
http://europepmc.org/articles/PMC3024281?pdf=render

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Early Target Cells of Measles Virus after Aerosol Infection of Non-Human Primates

Autor: Annelies W. Mesman, Martin Ludlow, Bertus K. Rima, Ken Lemon, Rik L. de Swart, Linda J. Rennick, Thijs Kuiken, Teunis B.H. Geijtenbeek, Selma Yüksel, Albert D. M. E. Osterhaus, W. Paul Duprex, Geert van Amerongen, Rory D. de Vries, Stephen McQuaid

Publikováno v: PLoS pathogens, 7(1). Public Library of Science
PLoS Pathogens, Vol 7, Iss 1, p e1001263 (2011)
PLoS Pathogens, 7(1). Public Library of Science
PLoS Pathogens (print), 7(1). Public Library of Science
PLoS Pathogens

Measles virus (MV) is highly infectious, and has long been thought to enter the host by infecting epithelial cells of the respiratory tract. However, epithelial cells do not express signaling lymphocyte activation molecule (CD150), which is the high-

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6a8dd651b51740626793b29cca5c43e
https://pure.amc.nl/en/publications/early-target-cells-of-measles-virus-after-aerosol-infection-of-nonhuman-primates(27fc2543-dffe-45f3-b9e9-5da36c908060).html

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HCMV spread and cell tropism are determined by distinct virus populations

Autor: Barbara Adler, Christian Sinzger, Hans Nitschko, Ulrich H. Koszinowski, Laura Scrivano

Publikováno v: PLoS Pathogens, Vol 7, Iss 1, p e1001256 (2011)
PLoS Pathogens

Human cytomegalovirus (HCMV) can infect many different cell types in vivo. Two gH/gL complexes are used for entry into cells. gH/gL/pUL(128,130,131A) shows no selectivity for its host cell, whereas formation of a gH/gL/gO complex only restricts the t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dbccdd8f31b2b6ec521bf1a8c02f8ca0
http://europepmc.org/articles/PMC3020925?pdf=render

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Whole-Body Analysis of a Viral Infection: Vascular Endothelium is a Primary Target of Infectious Hematopoietic Necrosis Virus in Zebrafish Larvae

Autor: Nuno Palha, Jean-Pierre Levraud, Philippe Herbomel, Michel Brémont, Marion Ludwig, Pierre Boudinot, Corinne Torhy, Emma Colucci-Guyon, Valérie Briolat

Publikováno v: Plos Pathogens 2 (7), . (2011)
PLoS Pathogens
PLoS Pathogens, Public Library of Science, 2011, 7 (2), pp.e1001269. ⟨10.1371/journal.ppat.1001269⟩
PLoS Pathogens, 2011, 7 (2), pp.e1001269. ⟨10.1371/journal.ppat.1001269⟩
PLoS Pathogens, Vol 7, Iss 2, p e1001269 (2011)

The progression of viral infections is notoriously difficult to follow in whole organisms. The small, transparent zebrafish larva constitutes a valuable system to study how pathogens spread. We describe here the course of infection of zebrafish early

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::366c24e29612b4815d00f1e8afd9aff3
http://prodinra.inra.fr/record/204433

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