NEAT1 long noncoding RNA regulates transcription via protein sequestration within subnuclear bodies

Autor: Hirose, T., Virnicchi, G., Tanigawa, A., Naganuma, T., Li, R., Kimura, Hiroshi, Yokoi, T., Nakagawa, S., Benard, M., Fox, A. H., Pierron, G.

Publikováno v: Molecular Biology of the Cell
Molecular Biology of the Cell, American Society for Cell Biology, 2014, 25 (1), pp.169-183. ⟨10.1091/mbc.E13-09-0558⟩
Molecular Biology of the Cell, 2014, 25 (1), pp.169-183. ⟨10.1091/mbc.E13-09-0558⟩

Paraspeckles are subnuclear structures formed around NEAT1 lncRNA. Paraspeckles became enlarged after proteasome inhibition caused by NEAT1 transcriptional activation, leading to protein sequestration into paraspeckles. The NEAT1-dependent sequestrat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7722bda4adae8ecb3587426ae53f636
http://hdl.handle.net/2115/54728