Manufacturing and Characterization of a Recombinant Adeno-Associated Virus Type 8 Reference Standard Material

Autor: Xinhua Zhang, Mauro Giacca, Mauricio R. Alvira, Xavier León, Catherine Pythoud, Alberto Auricchio, Lorena Zentilin, Will Fountain, Marcus Müller, Christophe Darmon, Martin Lock, Olivier Bockstael, Hiroaki Mizukami, Eduard Ayuso, Keiya Ozawa, Brigitte Weins, Susan P. McGorray, Kai Gao, Barbara Leuchs, Monica Doria, Yvet Noordman, Fatima Bosch, J. Fraser Wright, K. Reed Clark, Catherine Melas, Philippe Moullier, Véronique Blouin, Stephanie Bucher, Liliane Tenenbaum, Juergen Dr Kleinschmidt, Marina Sumaroka, Richard O. Snyder, Abdelwahed Chtarto, Inge van der Linden, Guangping Gao, Richard T. Surosky

Publikováno v: Human Gene Therapy
Human Gene Therapy, Mary Ann Liebert, 2014, 25 (11), pp.977-987. ⟨10.1089/hum.2014.057⟩
Human Gene Therapy, 2014, 25 (11), pp.977-987. ⟨10.1089/hum.2014.057⟩
Human Gene Therapy, vol. 25, no. 11, pp. 977-987

Gene therapy approaches using recombinant adeno-associated virus serotype 2 (rAAV2) and serotype 8 (rAAV8) have achieved significant clinical benefits. The generation of rAAV Reference Standard Materials (RSM) is key to providing points of reference

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f63fbfb64391b66e543280f2b0942e2c
https://europepmc.org/articles/PMC4236062/

Real-time quantitative reverse transcriptase-polymerase chain reaction as a method for determining lentiviral vector titers and measuring transgene expression

Autor: Suzanne L. Topalian, Richard A. Morgan, Nachimuthu Chinnasamy, Joeri L. Aerts, Gregory Lizée, Monica Gonzales

The use of lentiviral vectors for basic research and potential future clinical applications requires methodologies that can accurately determine lentiviral titers and monitor viral transgene expression within target cells, beyond the context of repor

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12a917833a7fbf5179d9b8bae61da0aa
https://hdl.handle.net/20.500.14017/7682518a-08eb-4445-b89f-74fbf81ef080

Enriching the Teaching of Biology with MATHEMATICAL CONCEPTS.

Autor: Andersen, Janet¹ jandersen@notes.cc.sunysb.edu

Publikováno v: American Biology Teacher (National Association of Biology Teachers). Apr2007, Vol. 69 Issue 4, p205-209. 5p. 1 Black and White Photograph, 3 Diagrams, 4 Charts, 2 Graphs.

Regulation and Genetics : Genetics of Animal Viruses

Autor: H. Fraenkel-Conrat

The time seems ripe for a critical compendum of that segment of the biological universe we call viruses. Virology, as a science, having passed only recently through its descriptive phase of naming and numbering, has probably reached that stage at whi