Zobrazeno 1 - 10
of 52
pro vyhledávání: '"Virinder Kaur Sarhadi"'
Autor:
Virinder Kaur Sarhadi, Gemma Armengol
Publikováno v:
Biomolecules, Vol 12, Iss 8, p 1021 (2022)
Molecular cancer biomarkers are any measurable molecular indicator of risk of cancer, occurrence of cancer, or patient outcome. They may include germline or somatic genetic variants, epigenetic signatures, transcriptional changes, and proteomic signa
Externí odkaz:
https://doaj.org/article/fbe5de207b224fa0badb91c9630c6181
Autor:
Heidelinde Sammallahti, Virinder Kaur Sarhadi, Arto Kokkola, Reza Ghanbari, Sama Rezasoltani, Hamid Asadzadeh Aghdaei, Pauli Puolakkainen, Sakari Knuutila
Publikováno v:
Biomolecules, Vol 12, Iss 5, p 652 (2022)
Pancreatic cancer (PC) is an aggressive malignancy with a dismal prognosis. To improve patient survival, the development of screening methods for early diagnosis is pivotal. Oncogenomic alterations present in tumor tissue are a suitable target for no
Externí odkaz:
https://doaj.org/article/5899769943704ca0ab84dc4a5396ca37
Autor:
Heidelinde Sammallahti, Arto Kokkola, Sama Rezasoltani, Reza Ghanbari, Hamid Asadzadeh Aghdaei, Sakari Knuutila, Pauli Puolakkainen, Virinder Kaur Sarhadi
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 23, p 12978 (2021)
Pancreatic cancer (PC) is an aggressive disease with a high mortality and poor prognosis. The human microbiome is a key factor in many malignancies, having the ability to alter host metabolism and immune responses and participate in tumorigenesis. Gu
Externí odkaz:
https://doaj.org/article/7d00e8275b534c0688fb993150aa4147
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 20, p 11035 (2021)
Osteosarcoma (OS) is an aggressive bone tumor that mainly affects children and adolescents. OS has a strong tendency to relapse and metastasize, resulting in poor prognosis and survival. The high heterogeneity and genetic complexity of OS make it cha
Externí odkaz:
https://doaj.org/article/0c844f25fa9d4950a87aae618d7aae54
Publikováno v:
BMC Cancer, Vol 17, Iss 1, Pp 1-9 (2017)
Abstract Background Distinct characteristic features categorize Merkel cell carcinoma (MCC) into two subgroups according to the Merkel cell polyomavirus infection. Many mutational studies on MCC have been carried out in recent years without identifyi
Externí odkaz:
https://doaj.org/article/61b42dc0999c4da0b90d60ad7ffeba68
Autor:
Farideh Saberi, Tiina Karla, Omar Youssef, Pauli Puolakkainen, Virinder Kaur Sarhadi, Arto Kokkola, Rasoul Salehi, Leo Lahti, Milja Tikkanen, Sakari Knuutila, Hilpi Rautelin
Publikováno v:
Anticancer Research. 40:1325-1334
Background/Aim: Gut microbiota plays an important role in colorectal cancer (CRC) and its composition in CRC patients can be influenced by ethnicity and tumour genomics. Herein, the aim was to study the possible associations of ethnicity and gene mut
Autor:
Satu Mäki-Nevala, Minna Nyström, Virinder Kaur Sarhadi, Sakari Knuutila, Anna Lepistö, Jukka-Pekka Mecklin, Ari Ristimäki, Laura Renkonen-Sinisalo, Päivi Peltomäki, Satu Valo
Publikováno v:
EBioMedicine
Background: DNA mismatch repair (MMR) defects are a major factor in colorectal tumorigenesis in Lynch syndrome (LS) and 15% of sporadic cases. Some adenomas from carriers of inherited MMR gene mutations have intact MMR protein expression implying oth
Autor:
Tiina Karla, Binu Mathew, Arto Kokkola, Milja Tikkanen, Hilpi Rautelin, Leo Lahti, Virinder Kaur Sarhadi, Pauli Puolakkainen, Sakari Knuutila
Publikováno v:
Gut Pathogens
Gut Pathogens, Vol 13, Iss 1, Pp 1-9 (2021)
Gut Pathogens, Vol 13, Iss 1, Pp 1-9 (2021)
Background Gastric adenocarcinoma is associated with H. pylori infection and inflammation that can result in the dysbiosis of gastric microbiota. The association of intestinal microbiota with gastric adenocarcinoma subtypes or with gastric gastrointe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1de8ac2334492200c0f94b045dfb2121
http://hdl.handle.net/10138/328379
http://hdl.handle.net/10138/328379
Autor:
Omar Youssef, Virinder Kaur Sarhadi, Tom Böhling, Aija Knuuttila, Päivi Piirilä, Sakari Knuutila
Publikováno v:
Anticancer Research. 38:5627-5634
Background: Genetic alterations occurring in lung cancer are the basis for defining molecular subtypes and essential for targeted therapies. Exhaled breath condensate (EBC) is a form of non-invasive sample that, amongst components, contains DNA from
Autor:
Milja Tikkanen, Pauli Puolakkainen, Monika Carpelan-Holmström, Sakari Knuutila, Tom Böhling, Homa Ehsan, Leo Lahti, Selja Koskensalo, Arto Kokkola, Hilpi Rautelin, Tiina Karla, Omar Youssef, Virinder Kaur Sarhadi
Publikováno v:
Digestive Diseases and Sciences
Background Microbial ecosystems that inhabit the human gut form central component of our physiology and metabolism, regulating and modulating both health and disease. Changes or disturbances in the composition and activity of this gut microbiota can