Novel Function of Tenascin-C, a Matrix Protein Relevant to Atherosclerosis, in Platelet Recruitment and Activation Under Flow

Autor: Gertraud Orend, Catherine Bourdon, Mathieu Schaff, Virginie Wurtz, Pierre Mangin, Nicolas Receveur, François Lanza, Christian Gachet, Cécile V. Denis

Publikováno v: Arteriosclerosis, Thrombosis, and Vascular Biology. 31:117-124

Objective— The identification of platelet-reactive proteins exclusively present in atherosclerotic plaques could provide interesting targets for effective and safe antithrombotic strategies. In this context, we explored platelet adhesion and activa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::faaadc3f6697b38a10eea5cecd034cf0
https://doi.org/10.1161/atvbaha.110.206375

The assembly of CD1e is controlled by an N-terminal propeptide which is processed in endosomal compartments

Autor: Blandine Maître, Catherine Angénieux, Virginie Wurtz, Emilie Layre, Martine Gilleron, Anthony Collmann, Sabrina Mariotti, Lucia Mori, Dominique Fricker, Jean-Pierre Cazenave, Alain van Dorsselaer, Christian Gachet, Gennaro de Libero, Germain Puzo, Daniel Hanau, Henri de La Salle

Publikováno v: Biochemical Journal; Vol 419
Biochemical Journal
Biochemical Journal, Portland Press, 2009, 419 (3), pp.661-668. ⟨10.1042/BJ20082204⟩
The Biochemical journal

CD1e displays unique features in comparison with other CD1 proteins. CD1e accumulates in Golgi compartments of immature dendritic cells and is transported directly to lysosomes, where it is cleaved into a soluble form. In these latter compartments, C

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db2fb6cb9a77bdf9d90337b802ce1a6d

Identification of five novel 14-3-3 isoforms interacting with the GPIb-IX complex in platelets

Autor: François Lanza, Christian Gachet, Tovo David, Nicolas Receveur, Virginie Wurtz, Pierre Mangin

Publikováno v: Journal of thrombosis and haemostasis : JTH. 7(9)

To cite this article: Mangin PH, Receveur N, Wurtz V, David T, Gachet C, Lanza F. Identification of five novel 14-3-3 isoforms interacting with the GPIbIX complex in platelets. J Thromb Haemost 2009; 7: 15505. Summary. Background: Binding of von Will

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https://pubmed.ncbi.nlm.nih.gov/19558434

An efficient protocol for the identification of protein phosphorylation in a seedless plant, sensitive enough to detect members of signalling cascades

Autor: Virginie Wurtz, Alain Van Dorsselaer, Dimitri Heintz, Anthony A. High, Ralf Reski, Eric Sarnighausen

Publikováno v: Electrophoresis. 25(7-8)

We describe a reproducible protocol to explore for the first time the phosphoproteome of a seedless plant, the moss Physcomitrella patens. Following tryptic digestion of a total protein extract, phosphorylated peptides were isolated using the combina

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8f58a572981c681af3c15cc71c92727
https://pubmed.ncbi.nlm.nih.gov/15095459

Lysosomal-Associated Transmembrane Protein 5 (LAPTM5) Is a Molecular Partner of CD1e

Autor: François Signorino-Gelo, Daniel Hanau, Alain Van Dorsselaer, Christian Gachet, Jean Salamero, François Waharte, Virginie Wurtz, Alexandre Gidon, Fabienne Proamer, Catherine Angénieux, Rim Hojeij

Publikováno v: PLoS ONE
PLoS ONE, Vol 7, Iss 8, p e42634 (2012)

The CD1e protein participates in the presentation of lipid antigens in dendritic cells. Its transmembrane precursor is transported to lysosomes where it is cleaved into an active soluble form. In the presence of bafilomycin, which inhibits vacuolar A

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::555295c78fadc4c46b739aaf8fefbb7c
https://doi.org/10.1371/journal.pone.0042634