Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Virginie Vignard"'
Autor:
Silvestre Cuinat, Stéphane Bézieau, Wallid Deb, Sandra Mercier, Virginie Vignard, Bertrand Isidor, Sébastien Küry, Frédéric Ebstein
Publikováno v:
Genes and Diseases, Vol 11, Iss 6, Pp 101130- (2024)
The recent advances in high throughput sequencing technology have drastically changed the practice of medical diagnosis, allowing for rapid identification of hundreds of genes causing human diseases. This unprecedented progress has made clear that mo
Externí odkaz:
https://doaj.org/article/4bb0294763224150ab0fc9342a19be84
Autor:
Virginie Vignard, Alban-Elouen Baruteau, Bérénice Toutain, Sandra Mercier, Bertrand Isidor, Richard Redon, Jean-Jacques Schott, Sébastien Küry, Stéphane Bézieau, Anne H. Monsoro-Burq, Frédéric Ebstein
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 12 (2024)
Neurodevelopmental proteasomopathies constitute a recently defined class of rare Mendelian disorders, arising from genomic alterations in proteasome-related genes. These alterations result in the dysfunction of proteasomes, which are multi-subunit pr
Externí odkaz:
https://doaj.org/article/8ec98747cd9e4fccb622ac05f5cea598
Autor:
Nathalie Labarrière, Sylvain Simon, Virginie Vignard, Tiffany Beauvais, Valentin Voillet, Camille Dabrowski, Nicolas Jouand, Amir Khammari, Cécile Braudeau, Régis Josien, Caroline Laheurte, François Aubin, Charles Nardin, Samuel Rulli, Raphael Gottardo, Candice D Church
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss 2 (2020)
Background Clinical benefit from programmed cell death 1 receptor (PD-1) inhibitors relies on reinvigoration of endogenous antitumor immunity. Nonetheless, robust immunological markers, based on circulating immune cell subsets associated with therape
Externí odkaz:
https://doaj.org/article/e9c7452d81254d408bd2276450f26642
Autor:
Nathalie Labarrière, Lucine Marotte, Sylvain Simon, Virginie Vignard, Emilie Dupre, Malika Gantier, Jonathan Cruard, Jean-Baptiste Alberge, Melanie Hussong, Cecile Deleine, Jean-Marie Heslan, Jonathan Shaffer, Tiffany Beauvais, Joelle Gaschet, Emmanuel Scotet, Delphine Fradin, Anne Jarry
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss 1 (2020)
BackgroundGenome editing offers unique perspectives for optimizing the functional properties of T cells for adoptive cell transfer purposes. So far, PDCD1 editing has been successfully tested mainly in chimeric antigen receptor T (CAR-T) cells and hu
Externí odkaz:
https://doaj.org/article/33f76b9d6e7146feb568dd7170c5ed8c
Autor:
Sylvain Simon, Zhong Wu, J. Cruard, Virginie Vignard, Agnes Fortun, Amir Khammari, Brigitte Dreno, Francois Lang, Samuel J. Rulli, Nathalie Labarriere
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Among Immunotherapeutic approaches for cancer treatment, the adoptive transfer of antigen specific T cells is still a relevant approach, that could have higher efficacy when further combined with immune check-point blockade. A high number of adoptive
Externí odkaz:
https://doaj.org/article/3fcadf62073e44acb63c75d632689c8d
Autor:
Tiphaine Delaunay, Mathilde Violland, Nicolas Boisgerault, Soizic Dutoit, Virginie Vignard, Christian Münz, Monique Gannage, Brigitte Dréno, Kristine Vaivode, Dace Pjanova, Nathalie Labarrière, Yaohe Wang, E. Antonio Chiocca, Fabrice Le Boeuf, John C. Bell, Philippe Erbs, Frédéric Tangy, Marc Grégoire, Jean-François Fonteneau
Publikováno v:
OncoImmunology, Vol 7, Iss 3 (2018)
Oncolytic immunotherapy using oncolytic viruses (OV) has been shown to stimulate the antitumor immune response by inducing the release of tumor-associated antigens (TAA) and danger signals from the dying infected tumor cells. In this study, we sought
Externí odkaz:
https://doaj.org/article/0e9355757cc9445b94db317476a79d85
Autor:
Mathilde Bobinet, Virginie Vignard, Laetitia Florenceau, Francois Lang, Nathalie Labarriere, Agnès Moreau-Aubry
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e75421 (2013)
The melanoma antigens MELOE-1 and MELOE-2 are encoded by a messenger, called meloe, overexpressed in melanomas compared with other tumour cell types and healthy tissues. They are both able to elicit melanoma-specific T cell responses in melanoma pati
Externí odkaz:
https://doaj.org/article/c77bf5b22fde4f0db0263c27d22b9484
Autor:
Delphine Carbonnelle, Virginie Vignard, Delphine Sehedic, Agnes Moreau-Aubry, Laetitia Florenceau, Maud Charpentier, Wolfgang Mikulits, Nathalie Labarriere, François Lang
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e75233 (2013)
Our previous studies on melanoma antigens identified two new polypeptides, named MELOE-1 and MELOE-2, that are involved in immunosurveillance. Intriguingly, these antigens are coded by distinct open reading frames (ORF) of the meloe mRNA which is sig
Externí odkaz:
https://doaj.org/article/1d1db63783204ef6b03048f3b617beab
Autor:
Mathilde Bobinet, Virginie Vignard, Anne Rogel, Amir Khammari, Brigitte Dreno, Francois Lang, Nathalie Labarriere
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e51716 (2012)
MELOE-1 is an overexpressed melanoma antigen containing a HLA-A2 restricted epitope, involved in melanoma immunosurveillance of patients adoptively transferred with tumour infiltrating lymphocytes (TIL). The use of the full-length antigen (46 aa) for
Externí odkaz:
https://doaj.org/article/91a7af20a71b4098b1545b6eee5152b8
Autor:
Mathilde Allard, Romain Oger, Virginie Vignard, Jean-Michel Percier, Giulia Fregni, Aurélie Périer, Anne Caignard, Béatrice Charreau, Karine Bernardeau, Amir Khammari, Brigitte Dréno, Nadine Gervois
Publikováno v:
PLoS ONE, Vol 6, Iss 6, p e21118 (2011)
BackgroundTumor-derived soluble factors, including soluble HLA molecules, can contribute to cancer immune escape and therefore impact on clinical course of malignant diseases. We previously reported that melanoma cells produce, in vitro, soluble form
Externí odkaz:
https://doaj.org/article/c84f2797c35e4618bb07920026322e0b