Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Virginie Menez"'
Autor:
Virginie Menez, Thomas Kergrohen, Tal Shasha, Claudia Silva-Evangelista, Ludivine Le Dret, Lucie Auffret, Chloé Subecz, Manon Lancien, Yassine Ajlil, Irma Segoviano Vilchis, Kévin Beccaria, Thomas Blauwblomme, Estelle Oberlin, Jacques Grill, David Castel, Marie-Anne Debily
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
We previously identified VRK3 as a specific vulnerability in DMG-H3K27M cells in a synthetic lethality screen targeting the whole kinome. The aim of the present study was to elucidate the mechanisms by which VRK3 depletion impact DMG-H3K27M cell fitn
Externí odkaz:
https://doaj.org/article/26038bc4491a447685806cef744f67b3
Autor:
Virginie Menez, Thomas Kergrohen, Tal Shasha, Claudia Silva-Evangelista, Ludivine Ledret, Lucie Auffret, Chloé Subecz, Manon Lancien, Yassine Ajlil, Kévin Beccaria, Thomas Blauwblomme, Estelle Oberlin, Jacques Grill, David Castel, Marie-Anne Debily
We previously identified VRK3 as a specific vulnerability in DMG-H3K27M cells in a synthetic lethality screen targeting the whole kinome. The aim of the present study was to elucidate the mechanisms by which VRK3 depletion impact DMG-K27M cell fitnes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::840f3545a75cc7ed258dccada61c5a0c
https://doi.org/10.1101/2023.03.24.533960
https://doi.org/10.1101/2023.03.24.533960
Autor:
Marie-Anne Debily, Virginie Menez
Publikováno v:
médecine/sciences
médecine/sciences, EDP Sciences, 2020, 36 (4), pp.326-329. ⟨10.1051/medsci/2020049⟩
médecine/sciences, 2020, 36 (4), pp.326-329. ⟨10.1051/medsci/2020049⟩
médecine/sciences, EDP Sciences, 2020, 36 (4), pp.326-329. ⟨10.1051/medsci/2020049⟩
médecine/sciences, 2020, 36 (4), pp.326-329. ⟨10.1051/medsci/2020049⟩
International audience; No abstract available
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3cf090de085964f0d9804fbb63bb1d61
https://hal.archives-ouvertes.fr/hal-02903925
https://hal.archives-ouvertes.fr/hal-02903925
Autor:
Thomas Kergrohen, Marie-Anne Debily, Kevin Beccaria, Emilie Barret, Estelle Oberlin, Jacques Grill, Jane Merlevede, Ambre Saccasyn, Claudia Silva-Evangelista, Stéphanie Puget, David Castel, Virginie Menez
Publikováno v:
Oncogene. 38(38)
Diffuse intrinsic pontine glioma (or DIPG) are pediatric high-grade gliomas associated with a dismal prognosis. They harbor specific substitution in histone H3 at position K27 that induces major epigenetic dysregulations. Most clinical trials failed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd5bd2d454567d06e51732f81aeafc63
https://pubmed.ncbi.nlm.nih.gov/31324890
https://pubmed.ncbi.nlm.nih.gov/31324890