Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Virginie Mansuy-Aubert"'
Publikováno v:
Frontiers in Physiology, Vol 14 (2023)
Metabolic disorders such as obesity and type 2 diabetes (T2D) are increasingly prevalent worldwide, necessitating a deeper comprehension of their underlying mechanisms. However, translating findings from animal research to human patients remains chal
Externí odkaz:
https://doaj.org/article/cb1ab4da420945959ed89e255708a756
Autor:
Virginie Mansuy-Aubert, Yann Ravussin
Publikováno v:
Frontiers in Neuroscience, Vol 17 (2023)
Short-chain fatty acids (SCFAs), produced by the metabolism of dietary fibers in the gut, have wide-ranging effects locally and throughout the body. They modulate the enteric and central nervous systems, benefit anti-inflammatory pathways, and serve
Externí odkaz:
https://doaj.org/article/fe3048b0ba2a4a779f81e31fe463fdfc
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract The prevalence of peripheral neuropathy is high in diabetic and overweight populations. Chronic neuropathic pain, a symptom of peripheral neuropathy, is a major disabling symptom that leads to a poor quality of life. Glucose management for d
Externí odkaz:
https://doaj.org/article/3934267ecc3544699aa125f929bc933b
Autor:
Jomana Hatahet, Tyler M. Cook, Raiza R. Bonomo, Nadia Elshareif, Chaitanya K. Gavini, Chelsea R. White, Jason Jesse, Virginie Mansuy-Aubert, Gregory Aubert
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 10 (2023)
More than 50% of patients with heart failure present with heart failure with preserved ejection fraction (HFpEF), and 80% of them are overweight or obese. In this study we developed an obesity associated pre-HFpEF mouse model and showed an improvemen
Externí odkaz:
https://doaj.org/article/2571248d5c164097bad987ebc3dcf512
Autor:
Chaitanya K. Gavini, Nadia Elshareif, Gregory Aubert, Anand V. Germanwala, Nigel A. Calcutt, Virginie Mansuy-Aubert
Publikováno v:
Journal of Neuroinflammation, Vol 19, Iss 1, Pp 1-14 (2022)
Abstract Background Peripheral neuropathy is a common and progressive disorder in the elderly that interferes with daily activities. It is of importance to find efficient treatments to treat or delay this age-related neurodegeneration. Silencing macr
Externí odkaz:
https://doaj.org/article/91929b57cb8741daa50a9e577295d26d
Communication between the gut microbiota and peripheral nervous system in health and chronic disease
Autor:
Tyler M. Cook, Virginie Mansuy-Aubert
Publikováno v:
Gut Microbes, Vol 14, Iss 1 (2022)
Trillions of bacteria reside within our gastrointestinal tract, ideally forming a mutually beneficial relationship between us. However, persistent changes in diet and lifestyle in the western diet and lifestyle contribute to a damaging of the gut mic
Externí odkaz:
https://doaj.org/article/2ff2e388235b4a32886bfd04cee22bea
Autor:
Sarah Talley, Raiza Bonomo, Chaitanya Gavini, Jomana Hatahet, Emily Gornick, Tyler Cook, Byeong Jae Chun, Pete Kekenes-Huskey, Gregory Aubert, Edward Campbell, Virginie Mansuy-Aubert
Publikováno v:
Disease Models & Mechanisms, Vol 15, Iss 6 (2022)
Obesity is an epidemic, and it is characterized by a state of low-grade systemic inflammation. A key component of inflammation is the activation of inflammasomes, multiprotein complexes that form in response to danger signals and that lead to activat
Externí odkaz:
https://doaj.org/article/d140b35e102c49a88ac585a76772fede
Publikováno v:
Frontiers in Neuroscience, Vol 16 (2022)
Externí odkaz:
https://doaj.org/article/11792642087f49cea8b350f6826d97f9
Autor:
Tyler M. Cook, Chaitanya K. Gavini, Jason Jesse, Gregory Aubert, Emily Gornick, Raiza Bonomo, Laurent Gautron, Brian T. Layden, Virginie Mansuy-Aubert
Publikováno v:
Molecular Metabolism, Vol 54, Iss , Pp 101350- (2021)
Objective: The vagus nerve provides a direct line of communication between the gut and the brain for proper regulation of energy balance and glucose homeostasis. Short-chain fatty acids (SCFAs) produced via gut microbiota fermentation of dietary fibe
Externí odkaz:
https://doaj.org/article/6021c23c9708486eb0d022d0dca9362c
Autor:
Chaitanya K. Gavini, Angie L. Bookout, Raiza Bonomo, Laurent Gautron, Syann Lee, Virginie Mansuy-Aubert
Publikováno v:
Cell Reports, Vol 25, Iss 2, Pp 271-277.e4 (2018)
Summary: Obesity is associated with many complications, including type 2 diabetes and painful neuropathy. There is no cure or prevention for obesity-induced pain, and the neurobiology underlying the onset of the disease is still obscure. In this stud
Externí odkaz:
https://doaj.org/article/da47ffdfcb4e4a60a63a84bba0bbe76a