Zobrazeno 1 - 10 of 27 pro vyhledávání: '"Virginie Maire"'
1
Akademický článek
HORMAD1 overexpression predicts response to anthracycline–cyclophosphamide and survival in triple‐negative breast cancers
Autor: Rania El‐Botty, Sophie Vacher, Juliette Mainguené, Adrien Briaux, Sabrina Ibadioune, Ahmed Dahmani, Elodie Montaudon, Fariba Nemati, Léa Huguet, Laura Sourd, Ludivine Morriset, Sophie Château‐Joubert, Thierry Dubois, Virginie Maire, Rosette Lidereau, Audrey Rapinat, David Gentien, Florence Coussy, Ivan Bièche, Elisabetta Marangoni
Publikováno v: Molecular Oncology, Vol 17, Iss 10, Pp 2017-2028 (2023)
Triple negative breast cancers (TNBCs) represent 15–20% of all breast cancers and are associated with higher recurrence and distant metastasis rate. Standard of care for early stage TNBC is anthracyclines combined with cyclophosphamide (AC) followe
Externí odkaz: https://doaj.org/article/544d9d964bc94114b651429060007609
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2
Akademický článek
Protein arginine methyltransferase 5: A novel therapeutic target for triple‐negative breast cancers
Autor: Mathilde Vinet, Samyuktha Suresh, Virginie Maire, Clarisse Monchecourt, Fariba Némati, Laetitia Lesage, Fabienne Pierre, Mengliang Ye, Auriane Lescure, Amélie Brisson, Didier Meseure, André Nicolas, Guillem Rigaill, Elisabetta Marangoni, Elaine Del Nery, Sergio Roman‐Roman, Thierry Dubois
Publikováno v: Cancer Medicine, Vol 8, Iss 5, Pp 2414-2428 (2019)
Abstract TNBC is a highly heterogeneous and aggressive breast cancer subtype associated with high relapse rates, and for which no targeted therapy yet exists. Protein arginine methyltransferase 5 (PRMT5), an enzyme which catalyzes the methylation of
Externí odkaz: https://doaj.org/article/e38d40999951432e94d1e8844dc31f54
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3
Akademický článek
Berberine Impairs the Survival of Triple Negative Breast Cancer Cells: Cellular and Molecular Analyses
Autor: Lamyae El Khalki, Virginie Maire, Thierry Dubois, Abdelmajid Zyad
Publikováno v: Molecules, Vol 25, Iss 3, p 506 (2020)
Triple negative breast cancer (TNBC) is an aggressive breast cancer subtype. Non-available targeted therapy for TNBC represents its biggest treatment challenge. Thus, finding new promising effective drugs is urgently needed. In the present study, we
Externí odkaz: https://doaj.org/article/9706738f96194197917d0ae88393d515
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4
Akademický článek
Transcriptome analysis of Wnt3a-treated triple-negative breast cancer cells.
Autor: Sylvie Maubant, Bruno Tesson, Virginie Maire, Mengliang Ye, Guillem Rigaill, David Gentien, Francisco Cruzalegui, Gordon C Tucker, Sergio Roman-Roman, Thierry Dubois
Publikováno v: PLoS ONE, Vol 10, Iss 4, p e0122333 (2015)
The canonical Wnt/β-catenin pathway is activated in triple-negative breast cancer (TNBC). The activation of this pathway leads to the expression of specific target genes depending on the cell/tissue context. Here, we analyzed the transcriptome of tw
Externí odkaz: https://doaj.org/article/22cc6d7761144873bd135a8f11c186f2
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5
Akademický článek
TTK/hMPS1 is an attractive therapeutic target for triple-negative breast cancer.
Autor: Virginie Maire, Céline Baldeyron, Marion Richardson, Bruno Tesson, Anne Vincent-Salomon, Eléonore Gravier, Bérengère Marty-Prouvost, Leanne De Koning, Guillem Rigaill, Aurélie Dumont, David Gentien, Emmanuel Barillot, Sergio Roman-Roman, Stéphane Depil, Francisco Cruzalegui, Alain Pierré, Gordon C Tucker, Thierry Dubois
Publikováno v: PLoS ONE, Vol 8, Iss 5, p e63712 (2013)
Triple-negative breast cancer (TNBC) represents a subgroup of breast cancers (BC) associated with the most aggressive clinical behavior. No targeted therapy is currently available for the treatment of patients with TNBC. In order to discover potentia
Externí odkaz: https://doaj.org/article/dcb4815980244faa8e17e979409ecdb7
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6
Akademický článek
The combinatorial PP1-binding consensus Motif (R/K)x( (0,1))V/IxFxx(R/K)x(R/K) is a new apoptotic signature.
Autor: Angélique N Godet, Julien Guergnon, Virginie Maire, Amélie Croset, Alphonse Garcia
Publikováno v: PLoS ONE, Vol 5, Iss 4, p e9981 (2010)
BACKGROUND: Previous studies established that PP1 is a target for Bcl-2 proteins and an important regulator of apoptosis. The two distinct functional PP1 consensus docking motifs, R/Kx((0,1))V/IxF and FxxR/KxR/K, involved in PP1 binding and cell deat
Externí odkaz: https://doaj.org/article/60d5dc00c6234215a27f4ae8a3e7e098
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