Výsledky vyhledávání - "Virginie Helies"

Akademický článek

Rabbit targeted genomic sequences after heterologous hybridization using human exome

Autor: Nathalie Iannuccelli, Julien Sarry, Yvon Billon, Patrick Aymard, Virginie Helies, Cédric Cabau, Cécile Donnadieu, Julie Demars

Publikováno v: BMC Research Notes, Vol 15, Iss 1, Pp 1-3 (2022)

Abstract Objective Causal mutations for major genes that underlie a broad range of morphological traits are often located within exons of genes that then affect protein functions. Non-model organism genetic studies are not easy to perform due to the

Externí odkaz: https://doaj.org/article/f2016182d8004fffab043d3df788ccd5

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Akademický článek

Multigenerational Effects of a Complex Human-Relevant Exposure during Folliculogenesis and Preimplantation Embryo Development: The FEDEXPO Study

Autor: Sara El Fouikar, Véronique Duranthon, Virginie Helies, Hélène Jammes, Anne Couturier-Tarrade, Véronique Gayrard, Nathalie Van Acker, François-Xavier Frenois, Catherine Archilla, Delphine Rousseau-Ralliard, Nicolas Gatimel, Roger Léandri

Publikováno v: Toxics, Vol 11, Iss 5, p 425 (2023)

Animal toxicological studies often fail to mimic the complexity of the human exposome, associating low doses, combined molecules and long-term exposure. Since the reproductive potential of a woman begins in the fetal ovary, the literature regarding t

Externí odkaz: https://doaj.org/article/5ddd3b63e72647358e47101a155c4028

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Akademický článek

Culture of rabbit caecum organoids by reconstituting the intestinal stem cell niche in vitro with pharmacological inhibitors or L-WRN conditioned medium

Autor: Eloïse Mussard, Cécile Pouzet, Virginie Helies, Géraldine Pascal, Sandra Fourre, Claire Cherbuy, Aude Rubio, Nathalie Vergnolle, Sylvie Combes, Martin Beaumont

Publikováno v: Stem Cell Research, Vol 48, Iss , Pp 101980- (2020)

Intestinal organoids are self-organized 3-dimensional (3D) structures formed by a single layer of polarized epithelial cells. This innovative in vitro model is highly relevant to study physiology of the intestinal epithelium and its role in nutrition

Externí odkaz: https://doaj.org/article/c61979e5767d400797dd6ce4414ed3cd

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Akademický článek

Folliculogenesis and steroidogenesis alterations after chronic exposure to a human-relevant mixture of environmental toxicants spare the ovarian reserve in the rabbit model

Autor: Sara El Fouikar, Nathalie Van Acker, Virginie Héliès, François-Xavier Frenois, Frank Giton, Véronique Gayrard, Yannick Dauwe, Laila Mselli-Lakhal, Delphine Rousseau-Ralliard, Natalie Fournier, Roger Léandri, Nicolas Gatimel

Publikováno v: Journal of Ovarian Research, Vol 17, Iss 1, Pp 1-18 (2024)

Abstract Background Industrial progress has led to the omnipresence of chemicals in the environment of the general population, including reproductive-aged and pregnant women. The reproductive function of females is a well-known target of endocrine-di

Externí odkaz: https://doaj.org/article/2ec46f82c5054568a2d93907c87e4a80

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Use of Mixture Dosing and Nonlinear Mixed Effect Modeling of Eight Environmental Contaminants in Rabbits to Improve Extrapolation Value of Toxicokinetic Data

Autor: Nicole Picard-Hagen, Pierre-Louis Toutain, Roger Leandri, Virginie Helies, Jean-Philippe Antignac, Véronique Gayrard, Jessika Moreau, Philippe Marchand

Publikováno v: Environmental Health Perspectives
Environmental Health Perspectives, National Institute of Environmental Health Sciences, 2021, 129 (11), pp.117006. ⟨10.1289/EHP8957⟩

Background: Although in vivo studies of internal exposure to hazardous substances have been carried out for many years, there is room for progress to improve their informative value while adhering to the four R’s: replacement, reduction, refinement

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::210c63c5d26b159cb05809214f51f073
https://hal.inrae.fr/hal-03497113/document

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Culture of rabbit caecum organoids by reconstituting the intestinal stem cell niche in vitro with pharmacological inhibitors or L-WRN conditioned medium

Autor: Nathalie Vergnolle, Claire Cherbuy, Eloïse Mussard, Géraldine Pascal, Virginie Helies, Martin Beaumont, Aude Rubio, Sylvie Combes, Cécile Pouzet, Sandra Fourre

Publikováno v: Stem Cell Research
Stem Cell Research, Elsevier, 2020, 48, pp.1-10. ⟨10.1016/j.scr.2020.101980⟩
Stem Cell Research, 2020, 48, pp.1-10. ⟨10.1016/j.scr.2020.101980⟩
Stem Cell Research, Vol 48, Iss, Pp 101980-(2020)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::107113fbb8ca247334f980b9050f55f2
https://hal.inrae.fr/hal-02983697/document

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Reconstitution of intestinal stem cell niche in vitro with pharmacological inhibitors or L-WRN conditioned medium differentially regulates epithelial proliferation, differentiation and barrier function in rabbit caecum organoids

Autor: Cécile Pouzet, Claire Cherbuy, Eloïse Mussard, Sandra Fourre, Aude Rubio, Virginie Helies, Nathalie Vergnolle, Martin Beaumont, Géraldine Pascal, Sylvie Combes

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7db3c49dfb441abcd85a347acdada0e5
https://doi.org/10.1101/2020.04.02.021550

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Les démarches participatives: un moyen pour faire évoluer conjointement les perceptions et les pratiques d'élevage dans la société et dans l'Institut ?

Autor: Laurence Fortun-Lamothe, Davi Savietto, Thierry Gidenne, Sylvie Combes, Yayu Huang, Patrick Aymard, Virginie Helies, Warin Laura, Nathalie Girard, Antoine Doré

Publikováno v: Séminaire Défis Scientifiques, Département de Physiologie Animale et Systèmes d’Elevage
Séminaire Défis Scientifiques, Département de Physiologie Animale et Systèmes d’Elevage, Nov 2019, Rennes, France
HAL

International audience; Les démarches participatives: un moyen pour faire évoluer conjointement les perceptions et les pratiques d'élevage dans la société et dans l'Institut ? Résumé Le bien-être des animaux d'élevage est une question qui in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::3ad854bfebd4d84f72413efaa6defe04
https://hal.inrae.fr/hal-02884253/file/2019seminaire.Phase(participa)LL(3L).pdf

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