Výsledky vyhledávání - "Virginie Geeraert"

State-specific Monoclonal Antibodies Identify an Intermediate State in Epsilon Protein Kinase C Activation

Autor: Gerda Endemann, Ivan Diamond, Daria Mochly-Rosen, Lina Yao, Hanita Khaner, Haibin Chen, Deborah Schechtman, Virginie Geeraert, Adrienne S. Gordon, Miriam C. Souroujon

Publikováno v: Journal of Biological Chemistry. 279:17617-17624

Evaluation of the activation state of protein kinase C (PKC) isozymes relies on analysis of subcellular translocation. A monoclonal antibody, 14E6, specific for the activated conformation of epsilonPKC, was raised using the first variable (V1) domain

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8dc19acf73af313fb7dcbe298138fe52
https://doi.org/10.1074/jbc.m400962200

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A moderate but not total decrease of mitochondrial membrane potential triggers apoptosis in neuron-like cells

Autor: Virginie Geeraert, Maïté Coppey-Moisan, Jacques Coppey, Christiane Durieux, Isabelle Gautier

Publikováno v: NeuroReport. 11:2953-2956

The effects of various degrees of perturbation of the mitochondrial membrane potential (mt delta psi) on apoptosis was investigated by intensified fluorescence digital-imaging microscopy on neuron-like cells, ND7. Mt delta psi was either decreased by

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e32c498bad2c6c3332903470796d30cb
https://doi.org/10.1097/00001756-200009110-00024

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F-actin does not modulate the initial steps of the protein kinase C activation process in living nerve cells

Autor: Agnes Janoshazi, Jean-Luc Dupont, Odile Procksch, Sylvette Chasserot-Golaz, Jean de Barry, Virginie Geeraert, Nancy J. Grant, Céline Huvet

Publikováno v: Experimental cell research. 289(2)

Actin is a major substrate for protein kinase C (PKC) and PKC is considered a modulator of the actin network. In addition in vitro studies (Biochemistry 39 (2000) 271) have suggested that all PKC isoforms bind to actin during the process of activatio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cecaa537e91f106575c8bcb0a5ee7c03
https://pubmed.ncbi.nlm.nih.gov/14499623

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A transient decrease of electrochemical gradient stabilizes DNA structural change in single mitochondria of living cells

Autor: Virginie Geeraert, Jacques Coppey, Maite Coppey-Moisan, Christiane Durieux, Anne-Christine Brunet

Publikováno v: Biology of the cell. 91(8)

The effect of controlled and reversible perturbation of the electrochemical gradient on the structural changes of mitochondrial DNA has been studied in living cells by fluorescence microscopy. Electrochemical gradient perturbations were induced by th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b42fe3f6886c506ef3c862ae1e72526
https://pubmed.ncbi.nlm.nih.gov/10629939

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