Number of lifetime menses increases breast cancer occurrence in postmenopausal women at high familial risk

Autor: Margaux Bieuville, Dominique Faugère, Virginie Galibert, Morgane Henard, Antoine M. Dujon, Beata Ujvari, Pascal Pujol, Benjamin Roche, Frédéric Thomas

Publikováno v: Frontiers in Ecology and Evolution, Vol 11 (2023)

It is increasingly thought that part of human susceptibility to cancer is the result of evolutionary mismatches: our ancestors evolved cancer suppression mechanisms in a world largely different from our modern environments. In that context, it has be

Externí odkaz: https://doaj.org/article/894a1e07df3948fcae3dee97700bdd17

Predominance of BRCA2 mutation and estrogen receptor-positive breast cancer among BRCA1/2 mutation carriers

Autor: Pascal Pujol, Kévin Yauy, Amandine Coffy, Nicolas Duforet-Frebourg, Sana Gabteni, Jean-Pierre Daurès, Frédérique Penault-Llorca, Frédéric Thomas, Kevin Hughes, Clare Turnbull, Virginie Galibert, Chloé Rideau, Laetitia Collet, Benoit You, David Geneviève, Nicolas Philippe

Publikováno v: Journal of Clinical Oncology. 40:551-551

Background: PARP inhibitor (PARPi) agents can improve progression-free survival of patients with breast cancer (BC) who carry a germline BRCA1 or BRCA2 pathogenic or likely pathogenic variant (gBRCA1/2) in both the metastatic and adjuvant setting. Th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::717527490d66e879bf61ee820bb837bd
https://doi.org/10.1200/jco.2022.40.16_suppl.551

Clinical practice guidelines for BRCA1 and BRCA2 genetic testing

Autor: Marion Vandromme, Jean Philippe Spano, Olivier Cussenot, Chloé Rideau, Carole Corsini, Isabelle Treilleux, Michèle Vintraud, Ignace Vergote, Yves-Jean Bignon, Kevin S. Hughes, Bernard Baertschi, Eitan Friedman, Daniel Zarca, Marie Duboys de Labarre, Pascal Pujol, Jean Marc Rey, Joseph Gligorov, Ettore D. Capoluongo, Clarisse Duriez, Marion Imbert-Bouteille, Yann Neuzillet, Jean-Louis Mandel, Isabelle Ray-Coquard, Laurence Gladieff, Jose E. Alés Martínez, Frédérique Penault-Llorca, Karim Fizazi, Pierre Jean Lamy, Julie A. Vendrell, Pascal Hammel, Thibault De La Motte Rouge, Jesus Garcia Foncillas, Diether Lambrechts, Tatiana Kogut-Kubiak, Karen Baudry, William Jacot, William D. Foulkes, Frédéric Thomas, Sophie Nambot, Massimo Barberis, Michèle Anahory, Matti Aapro, Xavier Rebillard, Josep M. Piulats, Florence Duchamp, Steven A. Narod, Sylviane Olschwang, Banu Arun, Marc Bollet, Philp Beer, Clare Turnbull, Helen Hanson, Nicola Normanno, Virginie Galibert

Publikováno v: Dipòsit Digital de la UB
Universidad de Barcelona
European Journal of Cancer
European Journal of Cancer, 2021, 146, pp.30-47. ⟨10.1016/j.ejca.2020.12.023⟩
European Journal of Cancer, Elsevier, 2021, 146, pp.30-47. ⟨10.1016/j.ejca.2020.12.023⟩

BRCA1 and BRCA2 gene pathogenic variants account for most hereditary breast cancer and are increasingly used to determine eligibility for PARP inhibitor (PARPi) therapy of BRCA-related cancer. Because issues of BRCA testing in clinical practice now o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d68784e83fff96e28dfb34c7477a991a
http://hdl.handle.net/2445/176353

Early onset breast cancer: differences in risk factors, tumor phenotype, and genotype between North African and South European women

Autor: Paul Vilquin, Virginie Galibert, Hesham El Ghazaly, Marie-Christine Picot, Paul Ihout, Helena Bertet, Asma Mouhout, Ahmed Gaballah, Karen Baudry, David Khayat, Alain Toledano, Yazid Belkacemi, Hamouda Boussen, Jean-Marc Rey, Céline Bourgier, Isabelle Coupier, Carole Corsini, Dalel Ben Nejima, Pascal Pujol, Sarra Henouda, Louise Biquard, Assia Bensalem, Faouzi Habib

Publikováno v: Breast Cancer Research and Treatment
Breast Cancer Research and Treatment, 2017, 166 (2), pp.631--639. ⟨10.1007/s10549-017-4434-y⟩

International audience; PURPOSE: This report compares the risk factors, the tumor phenotypes, and the BRCA1/BRCA2 genotype of early onset breast cancer (EOBC) patients between Southern Europe and North Africa. METHODS: Four hundred and fifty six wome

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76b69184eb317112a9d2fd465c4c6703
https://doi.org/10.1007/s10549-017-4434-y

Guidelines for reporting secondary findings of genome sequencing in cancer genes: the SFMPP recommendations

Autor: Daniel Zarca, Anne-Paule Gimenez-Roqueplo, Carole Corsini, Dominique Vaur, Nelly Burnichon, Sylviane Olschwang, Christian Hervé, Stéphane Richard, Virginie Galibert, Pascal Pujol, Nadem Soufir, Thierry Frebourg, I. Raingeard, Pierre Vande Perre, Sophie Giraud, Laurence Faivre, Xavier Rebillard, Michèle Anahory, Damien Sanlaville, Olivier Ingster, Muriel Le Bidan, Marc Spielmann, Alain Toledano, Anne Cambon-Thomsen, Brigitte Bressac-de Paillerets, Elisabeth Luporsi, Bernard Baertschi, David Azria, Olivier Cussenot, Pascal Hammel, Noëlle Bastide, Karen Baudry, Isabelle Coupier, Olivier Putois, Arash Rafii, Jean-Philippe Spano, Joseph Gligorov, Sarah Amar, Caroline Zorn, Patricia Niccoli, Michèle Vintraud, Anne-Sophie Lapointe, Olivier Caron, Jean-Marc Rey, David Geneviève, Pierre Le Coz

Publikováno v: European Journal of Human Genetics
European Journal of Human Genetics, 2018, 26 (12), pp.1732-1742. ⟨10.1038/s41431-018-0224-1⟩
European Journal of Human Genetics, Nature Publishing Group, 2018, 26 (12), pp.1732-1742. ⟨10.1038/s41431-018-0224-1⟩

IF 3.636 (2017); International audience; In oncology, the expanding use of multi-gene panels to explore familial cancer predisposition and tumor genome analysis has led to increased secondary findings discoveries (SFs) and has given rise to important

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8fe39cbca491f5aa5df412a9e2133e01
https://hal.umontpellier.fr/hal-01870352