Impaired interleukin-1beta and c-Fos expression in the hippocampus is associated with a spatial memory deficit in P2X(7) receptor-deficient mice.

Autor: Virginie F Labrousse, Laurence Costes, Agnès Aubert, Muriel Darnaudéry, Guillaume Ferreira, Thierry Amédée, Sophie Layé

Publikováno v: PLoS ONE, Vol 4, Iss 6, p e6006 (2009)

Recent evidence suggests that interleukin-1beta (IL-1beta), which was originally identified as a proinflammatory cytokine, is also required in the brain for memory processes. We have previously shown that IL-1beta synthesis in the hippocampus is depe

Externí odkaz: https://doaj.org/article/2a481af5f9604b8dbd5ad68d88f5259f

Dietary omega-3 deficiency exacerbates inflammation and reveals spatial memory deficits in mice exposed to lipopolysaccharide during gestation

Autor: Lionel Bretillon, Etienne Coutureau, Agnès Aubert, Sophie Layé, Quentin Leyrolle, Agnès Nadjar, Stéphane Grégoire, Corinne Joffre, Pierre Gressens, Virginie F. Labrousse, Camille Amadieu, Véronique Pallet, A. Sere

Publikováno v: Brain, Behavior, and Immunity
Brain, Behavior, and Immunity, Elsevier, 2018, 73, pp.427-440. ⟨10.1016/j.bbi.2018.06.004⟩
Labrousse, V F, Leyrolle, Q, Amadieu, C, Aubert, A, Sere, A, Coutureau, E, Grégoire, S, Bretillon, L, Pallet, V, Gressens, P, Joffre, C, Nadjar, A & Layé, S 2018, ' Dietary omega-3 deficiency exacerbates inflammation and reveals spatial memory deficits in mice exposed to lipopolysaccharide during gestation ', Brain, Behavior, and Immunity . https://doi.org/10.1016/j.bbi.2018.06.004

International audience; Maternal immune activation (MIA) is a common environmental insult on the developing brain and represents a risk factor for neurodevelopmental disorders. Animal models of in utero inflammation further revealed a causal link bet

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95a08f20742f339b5e1319b9472c25fd
https://pubmed.ncbi.nlm.nih.gov/30009995

Endocytosis of the Glutamate Receptor Subunit GluK3 Controls Polarized Trafficking

Autor: Christophe Mulle, Françoise Coussen, Virginie F. Labrousse, David Perrais, Deborah Huyghe, Julien Veran

Publikováno v: The Journal of Neuroscience. 31:11645-11654

Kainate receptors (KARs) are widely expressed in the brain and are present at both presynaptic and postsynaptic sites. GluK3-containing KARs are thought to compose presynaptic autoreceptors that facilitate hippocampal mossy fiber synaptic transmissio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6484111e1b0cffa1609f7fd2e3175c41
https://doi.org/10.1523/jneurosci.2206-11.2011

Dietary n-3-polyunsaturated fatty acid deprivation and cytokine signaling pathways in the brain

Autor: Virginie F. Labrousse, Véronique De Smedt-Peyrusse, Sophie Layé

Publikováno v: Handbook of Behavior, Food and Nutrition
Handbook of Behavior, Food and Nutrition, Springer Science-Business Media Deutschland GmbH, 2011, 978-1441917867. ⟨10.1007/978-0-387-92271-3_115⟩
Handbook of Behavior, Food and Nutrition ISBN: 9780387922706

Partie 20, Chapitre 115; International audience; The innate immune system of the brain is principally composed of microglial cells and astrocytes, which, once activated, protect neurons against insults (infectious agents, lesions, etc.). Activated gl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fbbe855dbf4222a4a26bafcd06bcc233
https://hal.inrae.fr/hal-02808194

Impaired Interleukin-1β and c-Fos Expression in the Hippocampus Is Associated with a Spatial Memory Deficit in P2X7 Receptor-Deficient Mice

Autor: Thierry Amédée, Laurence Costes, Guillaume Ferreira, Muriel Darnaudéry, Agnès Aubert, Virginie F. Labrousse, Sophie Layé

Publikováno v: PLoS ONE
PLoS ONE, Vol 4, Iss 6, p e6006 (2009)
PLoS ONE, Public Library of Science, 2009, 4 (6), 9 p. (e6006). ⟨10.1371/journal.pone.0006006⟩
Plos One 6 (4), 9 p. (e6006). (2009)

Recent evidence suggests that interleukin-1beta (IL-1beta), which was originally identified as a proinflammatory cytokine, is also required in the brain for memory processes. We have previously shown that IL-1beta synthesis in the hippocampus is depe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::393dce60bb55df8d0f44d8655324822b
http://europepmc.org/articles/PMC2695542