Výsledky vyhledávání - "Virginie Dubosclard"

Akademický článek

Structure and functional analysis of the RNA- and viral phosphoprotein-binding domain of respiratory syncytial virus M2-1 protein.

Autor: Marie-Lise Blondot, Virginie Dubosclard, Jenna Fix, Safa Lassoued, Magali Aumont-Nicaise, François Bontems, Jean-François Eléouët, Christina Sizun

Publikováno v: PLoS Pathogens, Vol 8, Iss 5, p e1002734 (2012)

Respiratory syncytial virus (RSV) protein M2-1 functions as an essential transcriptional cofactor of the viral RNA-dependent RNA polymerase (RdRp) complex by increasing polymerase processivity. M2-1 is a modular RNA binding protein that also interact

Externí odkaz: https://doaj.org/article/9ce5ff1c455d4da78dc075aead552d90

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Receptor-Based Artificial Metalloenzymes on Living Human Cells

Autor: Virginie Dubosclard, Audrey Bendelac, Wadih Ghattas, Arne Wick, Jean-Pierre Mahy, Régis Guillot, Rémy Ricoux

Publikováno v: Journal of the American Chemical Society. 140:8756-8762

Artificial metalloenzymes are known to be promising tools for biocatalysis, but their recent compartmentalization has led to compatibly with cell components thus shedding light on possible therapeutic applications. We prepared and characterized artif

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::387e4b4fc28ce938b00f5ce6ba15c9e6
https://doi.org/10.1021/jacs.8b04326

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Crystal structure of phosphomannose isomerase fromCandida albicanscomplexed with 5‐phospho‐d‐arabinonhydrazide

Autor: Herman van Tilbeurgh, Lama Ahmad, Inès Li de la Sierra-Gallay, Noureddine Lazar, S. Plancqueel, Wadih Ghattas, Virginie Dubosclard, Laurent Salmon

Publikováno v: FEBS Letters
FEBS Letters, Wiley, 2018, 592 (10), pp.1667--1680. ⟨10.1002/1873-3468.13059⟩
FEBS Letters, 2018, 592 (10), pp.1667--1680. ⟨10.1002/1873-3468.13059⟩

International audience; Type I phosphomannose isomerases (PMIs) are zinc-dependent monofunctional metalloenzymes catalysing the reversible isomerization of d-mannose 6-phosphate to d-fructose 6-phosphate. 5-Phospho-d-arabinonhydrazide (5PAHz), design

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3185d98452e04dec11c6591cfe356955
https://doi.org/10.1002/1873-3468.13059

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CuII ‐Containing 1‐Aminocyclopropane Carboxylic Acid Oxidase Is an Efficient Stereospecific Diels–Alderase

Autor: Morane Beaumet, Jean-Pierre Mahy, Régis Guillot, A. Jalila Simaan, Marius Réglier, Sybille Tachon, Virginie Dubosclard, Wadih Ghattas

Publikováno v: Angewandte Chemie
Angewandte Chemie, 2019, 131 (41), pp.14747-14751. ⟨10.1002/ange.201909407⟩
Angewandte Chemie, Wiley-VCH Verlag, 2019, 131 (41), pp.14747-14751. ⟨10.1002/ange.201909407⟩

International audience; In the context of developing eco-friendly chemistry, artificial enzymes are now considered as promising tools for synthesis. They are prepared in particular with the aim to catalyze reactions that are rarely, if ever, catalyze

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d933f970280b52ef60dfb7cda04f462
https://hal.science/hal-02299031/document

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Autor: Wadih, Ghattas, Virginie, Dubosclard, Sybille, Tachon, Morane, Beaumet, Régis, Guillot, Marius, Réglier, A Jalila, Simaan, Jean-Pierre, Mahy

Publikováno v: Angewandte Chemie (International ed. in English). 58(41)

In the context of developing ecofriendly chemistry, artificial enzymes are now considered as promising tools for synthesis. They are prepared in particular with the aim to catalyze reactions that are rarely, if ever, catalyzed by natural enzymes. We

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::fbb9480a822dbebed9ff52cf1bd36e7d
https://pubmed.ncbi.nlm.nih.gov/31487113

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Lack of interaction between NEMO and SHARPIN impairs linear ubiquitination and NF-?B activation and leads to incontinentia pigmenti

Autor: Virginie Dubosclard, Yamina Hamel, Elodie Bal, Capucine Picard, Alessandra Pescatore, Christine Bodemer, Emmanuel Laplantine, Ghislaine Royer, Smail Hadj-Rabia, Robert Weil, Arnold Munnich, Jean-Paul Bonnefont, J Steffann, Fabrice Agou, Jean-Laurent Casanova, Pierre Vabres, Asma Smahi, Valeria M. Ursini, Bertrand Boisson

Publikováno v: Journal of allergy and clinical immunology 140 (2017): 1671–1682.e2. doi:10.1016/j.jaci.2016.11.056
info:cnr-pdr/source/autori:Bal E, Laplantine E, Hamel Y, Dubosclard V, Boisson B, Pescatore A, Picard C, Hadj-Rabia S, Royer G, Steffann J, Bonnefont JP, Ursini VM, Vabres P, Munnich A, Casanova JL, Bodemer C, Weil R, Agou F, Smahi A./titolo:Lack of interaction between NEMO and SHARPIN impairs linear ubiquitination and NF-?B activation and leads to incontinentia pigmenti./doi:10.1016%2Fj.jaci.2016.11.056/rivista:Journal of allergy and clinical immunology/anno:2017/pagina_da:1671/pagina_a:1682.e2/intervallo_pagine:1671–1682.e2/volume:140
Journal of Allergy and Clinical Immunology
Journal of Allergy and Clinical Immunology, Elsevier, 2017, 17 (4), ⟨10.1016/j.jaci.2016.11.056⟩
Journal of Allergy and Clinical Immunology, 2017, 17 (4), ⟨10.1016/j.jaci.2016.11.056⟩
Journal of Allergy and Clinical Immunology, Elsevier, 2017, 17 (4), 〈10.1016/j.jaci.2016.11.056〉

International audience; BackgroundIncontinentia pigmenti (IP; MIM308300) is a severe, male-lethal, X-linked, dominant genodermatosis resulting from loss-of-function mutations in the IKBKG gene encoding nuclear factor κB (NF-κB) essential modulator

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::392cf4baa355a64ff5044ba935852cea

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A new subunit vaccine based on nucleoprotein nanoparticles confers partial clinical and virological protection in calves against bovine respiratory syncytial virus

Autor: Jean-François Eléouët, Julie Bernard, Nathalie Castagné, Guillaume Durand, Marion Soulestin, Sébastien Deville, Sabine Riffault, Catherine Dubuquoy, Virginie Dubosclard, Agnès Petit-Camurdan, Gilles Meyer, Philippe Bernardet, Florence Bernex, Martine Deplanche, Isabelle Schwartz-Cornil

Publikováno v: Vaccine
Vaccine, Elsevier, 2010, 28 (21), pp.3722-3734. ⟨10.1016/j.vaccine.2010.03.008⟩

Chantier qualité GA; International audience; Human and bovine respiratory syncytial viruses (HRSV and BRSV) are two closely related, worldwide prevalent viruses that are the leading cause of severe airway disease in children and calves, respectively

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29a2d5a3cf85203e8c320812bd4ad545
http://europepmc.org/articles/PMC7115569

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The Respiratory Syncytial Virus M2-1 Protein Forms Tetramers and Interacts with RNA and P in a Competitive Manner

Autor: Thi-Lan Tran, Julie Bernard, Sylvie Noinville, Jean-François Eléouët, Nathalie Castagné, Robert P. Yeo, Emmanuelle Koch, Céline Henry, Virginie Dubosclard, Mohammed Moudjou

Publikováno v: Journal of Virology
Journal of Virology, American Society for Microbiology, 2009, 83 (13), pp.6363-6374. ⟨10.1128/JVI.00335-09⟩

The respiratory syncytial virus (RSV) M2-1 protein is an essential cofactor of the viral RNA polymerase complex and functions as a transcriptional processivity and antitermination factor. M2-1, which exists in a phosphorylated or unphosphorylated for

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b0612dcd8d76aff202db2e5b3bb2455
https://doi.org/10.1128/jvi.00335-09

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Use of fluorescence spectroscopy for quantitative investigations of ubiquitin interactions with the ubiquitin-binding domains of NEMO

Autor: Virginie, Dubosclard, Elisabeth, Fontan, Fabrice, Agou

Publikováno v: Methods in molecular biology (Clifton, N.J.). 1280

Ubiquitin serves as a signal for a variety of cellular processes and its specific interaction with ubiquitin-binding domain (UBD) regulates key cellular events including protein degradation, cell-cycle control, DNA repair, and kinase activation. Seve

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::334e527f98f34aefb86176b9a481bfe3
https://pubmed.ncbi.nlm.nih.gov/25736758

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Use of Fluorescence Spectroscopy for Quantitative Investigations of Ubiquitin Interactions with the Ubiquitin-Binding Domains of NEMO

Autor: Fabrice Agou, Elisabeth Fontan, Virginie Dubosclard

Publikováno v: NF-Kappa B Methods and Protocols
NF-Kappa B Methods and Protocols, 1280, pp.321-337, 2015, NF-Kappa B Methods in Molecular Biology, ⟨10.1007/978-1-4939-2422-6_19⟩
Methods in Molecular Biology ISBN: 9781493924219

International audience; Ubiquitin serves as a signal for a variety of cellular processes and its specifi c interaction with ubiquitin-binding domain (UBD) regulates key cellular events including protein degradation, cell-cycle control, DNA repair, an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65dcab36aca36860f4acbef52609145b
https://hal-pasteur.archives-ouvertes.fr/pasteur-01128925

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