Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Virginie Deleuze"'
Autor:
Virginie Deleuze, Leonor Garcia, Betty Rouaisnel, Mohammad Salma, Alexia Kinoo, Charlotte Andrieu-Soler, Eric Soler
Publikováno v:
iScience, Vol 26, Iss 9, Pp 107641- (2023)
Summary: Targeted genome editing holds great promise in biology. However, efficient genome modification, including gene knock-in (KI), remains an unattained goal in multiple cell types and loci due to poor transfection efficiencies and low target gen
Externí odkaz:
https://doaj.org/article/e9c57e401ae043b4b42f350399245f49
Autor:
Sophie Guelfi, Béatrice Orsetti, Virginie Deleuze, Valérie Rigau, Luc Bauchet, Hugues Duffau, Bernard Rothhut, Jean-Philippe Hugnot
Publikováno v:
Cancers, Vol 13, Iss 21, p 5393 (2021)
Glioblastomas (GBM) are high-grade brain tumors, containing cells with distinct phenotypes and tumorigenic potentials, notably aggressive and treatment-resistant multipotent glioblastoma stem cells (GSC). The molecular mechanisms controlling GSC plas
Externí odkaz:
https://doaj.org/article/b81289e9aded462483d1b85239e24bd9
Autor:
Virginie Deleuze, Rawan El-Hajj, Elias Chalhoub, Christiane Dohet, Valérie Pinet, Philippe Couttet, Danièle Mathieu
Publikováno v:
PLoS ONE, Vol 7, Iss 7, p e40484 (2012)
The two related basic helix-loop-helix, TAL1 and LYL1, and their cofactor LIM-only-2 protein (LMO2) are present in blood and endothelial cells. While their crucial role in early hematopoiesis is well established, their function in endothelial cells a
Externí odkaz:
https://doaj.org/article/a6e243ce9cb242928f868d918de08632
Publikováno v:
Blood Cells, Molecules, and Diseases. 101:102745
Autor:
Valérie Rigau, Jean-Philippe Hugnot, Luc Bauchet, Sophie Guelfi, Bernard Rothhut, Virginie Deleuze, Hugues Duffau, Béatrice Orsetti
Publikováno v:
Cancers
Cancers, 2021, 13 (21), pp.5393. ⟨10.3390/cancers13215393⟩
Cancers, Vol 13, Iss 5393, p 5393 (2021)
Volume 13
Issue 21
Cancers, 2021, 13 (21), pp.5393. ⟨10.3390/cancers13215393⟩
Cancers, Vol 13, Iss 5393, p 5393 (2021)
Volume 13
Issue 21
Simple Summary Glioblastoma multiforme is the most aggressive form of brain tumor and is still incurable. These neoplasms are particularly difficult to treat efficiently because of their highly heterogeneous and resistant characteristics. Advances in
Autor:
Danièle Mathieu, Virginie Deleuze, Leila El Kebriti, Abid Hussain, Hulya Turali, Yaël Glasson, Nelly Pirot, Valérie Pinet
Publikováno v:
Stem Cells / Stem Cells (Miamisburg)
Stem Cells / Stem Cells (Miamisburg), Alphamed Press, 2021, ⟨10.1002/stem.3286⟩
Stem Cells / Stem Cells (Miamisburg), Alphamed Press, 2021, ⟨10.1002/stem.3286⟩
Lyl1 encodes a hematopoietic- and endothelial-specific bHLH transcription factor. Lyl1-deficient mice are viable, but they display mild hematopoietic and vascular defects. Specifically, LYL1 is required for the maturation and stabilization of blood v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4624b9d49f04c6d9d31e5435698cc335
https://hal.archives-ouvertes.fr/hal-03022048
https://hal.archives-ouvertes.fr/hal-03022048
Autor:
Silvia Salmoiraghi, Daniel Birnbaum, Loïc Garçon, Frederik Otzen Bagger, Zakia Aid, Alexandre Fagnan, Benjamin Uzan, Stephane de Botton, Maria Riera Piqué-Borràs, Cécile K. Lopez, Christine Dierks, Connor Sweeney, Eric Delabesse, Juerg Schwaller, Elie Robert, Kazuya Shimoda, Zahra Kadri, Thomas Pabst, Jaroslaw P. Maciejewski, Betty Leite, Alexis Caulier, Sébastien Malinge, Samantha Tauchmann, Catherine Carmichael, Amina Kurtovic-Kozaric, Olivier A. Bernard, Virginie Deleuze, Ute M. Moll, Paresh Vyas, Martin Carroll, Veronique De Mas, Orietta Spinelli, Thomas Mercher, Hélène Lapillonne, Cathy Ignacimouttou, Charles G. Mullighan, Eric Soler, V. Gelsi-Boyer, Peter Valent, Cécile Thirant, Jean Baptiste Micol, Eduardo Anguita, Ilaria Iacobucci, Benjamin T. Kile
Publikováno v:
Blood
Blood, American Society of Hematology, 2020, 136 (6), pp.698-714. ⟨10.1182/blood.2019003062⟩
Blood, American Society of Hematology, 2020, 136 (6), pp.698-714. ⟨10.1182/blood.2019003062⟩
Acute erythroleukemia (AEL or acute myeloid leukemia [AML]-M6) is a rare but aggressive hematologic malignancy. Previous studies showed that AEL leukemic cells often carry complex karyotypes and mutations in known AML-associated oncogenes. To better
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc1611df63d3e6c6a4c23f7a9b703562
https://hal.archives-ouvertes.fr/hal-03022044/document
https://hal.archives-ouvertes.fr/hal-03022044/document
Autor:
Abid, Hussain, Virginie, Deleuze, Leila, El Kebriti, Hulya, Turali, Nelly, Pirot, Yaël, Glasson, Danièle, Mathieu, Valérie, Pinet
Publikováno v:
Stem Cells (Dayton, Ohio)
Lyl1 encodes a hematopoietic‐ and endothelial‐specific bHLH transcription factor. Lyl1‐deficient mice are viable, but they display mild hematopoietic and vascular defects. Specifically, LYL1 is required for the maturation and stabilization of b
Autor:
Isabel C. Lopez-Mejia, Jamal Tazi, Jean Marie Blanchard, Virginie Deleuze, Marie-Luce Vignais, Flavio Della Seta, Marion de Toledo, Christian Jorgensen, Cosette Rebouissou, Patrick Fafet
Publikováno v:
Molecular Biology of the Cell
Molecular and Cellular Biology
Molecular and Cellular Biology, American Society for Microbiology, 2013, 24 (20), pp.3164-3176. ⟨10.1091/mbc.E13-03-0142)⟩
Molecular and Cellular Biology, 2013, 24 (20), pp.3164-3176. ⟨10.1091/mbc.E13-03-0142)⟩
Molecular Biology of the Cell, American Society for Cell Biology, 2013, 24 (20), pp.3164-76. ⟨10.1091/mbc.E13-03-0142⟩
Molecular Biology of the Cell, vol. 24, no. 20, pp. 3164-3176
Molecular and Cellular Biology
Molecular and Cellular Biology, American Society for Microbiology, 2013, 24 (20), pp.3164-3176. ⟨10.1091/mbc.E13-03-0142)⟩
Molecular and Cellular Biology, 2013, 24 (20), pp.3164-3176. ⟨10.1091/mbc.E13-03-0142)⟩
Molecular Biology of the Cell, American Society for Cell Biology, 2013, 24 (20), pp.3164-76. ⟨10.1091/mbc.E13-03-0142⟩
Molecular Biology of the Cell, vol. 24, no. 20, pp. 3164-3176
Matching sets of human primary fibroblasts cocultured with placenta explants are used to compare tissue capacities to support trophoblast invasion. Substituting endometrium with dermis dramatically reduces EVCT interstitial invasion, a phenomenon rel
Autor:
Fred Sablitzky, Danièle Mathieu, Philippe Couttet, Christiane Dohet, Rawan El-Hajj, Valérie Pinet, Nelly Pirot, Virginie Deleuze
Publikováno v:
Blood
Blood, American Society of Hematology, 2010, 115 (25), pp.5270-9. ⟨10.1182/blood-2010-03-275651⟩
Blood, American Society of Hematology, 2010, 115 (25), pp.5270--9. ⟨10.1182/blood-2010-03-275651⟩
Blood, American Society of Hematology, 2010, 115 (25), pp.5270-9. ⟨10.1182/blood-2010-03-275651⟩
Blood, American Society of Hematology, 2010, 115 (25), pp.5270--9. ⟨10.1182/blood-2010-03-275651⟩
The 2 related basic helix loop helix genes, LYL1 and TAL-1 are active in hematopoietic and endothelial lineages. While Tal-1 is essential for both hematopoietic and vascular development, the role of Lyl1 appears to be distinct as deficient mice are v