Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Virginie Cano"'
Publikováno v:
Life Sciences. 61:PL1-PL8
A series of inhibitors of the human liver recombinant UDP-glucuronosyltransferase 1 ∗ 6 derived from uridine were synthetized as probes of the binding site of the cosubstrate, UDP-glucuronic acid. If triphenylmethanol or uridine alone failed to inh
Autor:
Jean-Claude Ziegler, Abdelaziz Elass, Alain Cartier, Eric Battaglia, Mourad Said, Sylvie Fournel-Gigleux, Gérard Vergoten, Jacques Magdalou, Marie-Hélène Livertoux, Virginie Cano
Publikováno v:
Journal of biochemical and molecular toxicology. 12(1)
A series of potent and competitive inhibitors of UDP-glucuronosyltransferase derived from 7,7,7-triphenylheptanoic acid has been synthesized in order to probe the active site of the isozyme involved in the glucuronidation of the endogenous toxic comp