Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Virginie Aiello"'
Autor:
Marine De Burghgrave, Chloé Lourenço, Claire Berthault, Virginie Aiello, Adrian Villalba, Alexis Fouque, Marc Diedisheim, Sylvaine You, Masaya Oshima, Raphaël Scharfmann
Publikováno v:
Cells, Vol 12, Iss 1, p 113 (2022)
Type 1 diabetes (T1D) is an auto-immune disease characterized by the progressive destruction of insulin-producing pancreatic beta cells. While beta cells are the target of the immune attack, the other islet endocrine cells, namely the alpha and delta
Externí odkaz:
https://doaj.org/article/03a6c7e06e924b0ca3a3e1da21ff08f1
Autor:
Olivier Albagli, Raphael Scharfmann, Latif Rachdi, Lukas Huijbregts, Virginie Aiello, Andrea Soggia, Philippe Ravassard
Publikováno v:
Islets. 13:10-23
During the secondary transition of rodent pancreatic development, mainly between E12.5 and E15.5 in mice, exocrine and endocrine populations differentiate from pancreatic progenitors. Here we descr...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::613eee914b2ab5f42af49e49e391f66e
https://doi.org/10.1080/19382014.2020.1863723
https://doi.org/10.1080/19382014.2020.1863723
Autor:
Latif Rachdi, Mattias Hansson, Maja Borup Kjær Petersen, Raphael Scharfmann, Claire Berthault, Anne Grapin-Botton, Lukas Huijbregts, Virginie Aiello, Christian Honoré
Publikováno v:
Diabetes. 68:761-773
Bromodomain and extraterminal (BET) proteins are epigenetic readers that interact with acetylated lysines of histone tails. Recent studies have demonstrated their role in cancer progression because they recruit key components of the transcriptional m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::612c4bbaf62c3fd10b1b5f0e508b8c0c
https://doi.org/10.2337/db18-0224
https://doi.org/10.2337/db18-0224
Autor:
Lukas, Huijbregts, Virginie, Aiello, Andrea, Soggia, Philippe, Ravassard, Latif, Rachdi, Raphaël, Scharfmann, Olivier, Albagli
Publikováno v:
Islets
During the secondary transition of rodent pancreatic development, mainly between E12.5 and E15.5 in mice, exocrine and endocrine populations differentiate from pancreatic progenitors. Here we describe an experimental system for its study in vitro. Fi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d6219599a492497b4a577815d4409b84
https://pubmed.ncbi.nlm.nih.gov/33641620
https://pubmed.ncbi.nlm.nih.gov/33641620
Autor:
Raphael Scharfmann, Carmen Capito, Yves Aigrain, Anne Clark, Philippe Ravassard, Marie-Thérèse Simon, Virginie Aiello
Publikováno v:
Diabetes; Vol 62
Diabetes
Diabetes
While sporadic human genetic studies have permitted some comparisons between rodent and human pancreatic development, the lack of a robust experimental system has not permitted detailed examination of human pancreatic development. We previously devel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::578a814c7d9eda8a5df3dcb295911666
Publikováno v:
Diabetes
Leucine (Leu) is an essential branched-chain amino acid, which activates the mammalian target of rapamycin (mTOR) signaling pathway. The effect of Leu on cell differentiation during embryonic development is unknown. Here, we show that Leu supplementa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f622e9b337553e0b3c1c49bd1951d85e
https://doi.org/10.2337/db11-0765
https://doi.org/10.2337/db11-0765
Autor:
Myriam Attali, A. Basmaciogullari, Maria A. Zanta-Boussif, Raphael Scharfmann, Volodymyr Stetsyuk, Virginie Aiello, Bertrand Duvillié
Publikováno v:
Diabetes. 56:1248-1258
The importance of mesenchymal-epithelial interactions for normal development of the pancreas was recognized in the early 1960s, and mesenchymal signals have been shown to control the proliferation of early pancreatic progenitor cells. The mechanisms
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::420e850c72cc27f88532f2da8efe786e
https://doi.org/10.2337/db06-1307
https://doi.org/10.2337/db06-1307
Publikováno v:
Diabetes. 52:2035-2042
Islets of Langerhans are micro-organs scattered throughout the pancreas that contain insulin-producing cells, called beta-cells. Although new light has been recently shed on beta-cell development, information on the phenotype and location of beta-ste
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fa8335d229b1072dcb3e1e6ad3c470d0
https://doi.org/10.2337/diabetes.52.8.2035
https://doi.org/10.2337/diabetes.52.8.2035
Autor:
Dulanjalee Kariyawasam, Virginie Aiello, Jean-Maurice Delabar, Michel Polak, Raphael Scharfmann, Nathalie Janel, Latif Rachdi, Yann Herault
Publikováno v:
Cell cycle (Georgetown, Tex.). 13(14)
Type 2 diabetes is caused by a limited capacity of insulin-producing pancreatic β cells to increase their mass and function in response to insulin resistance. The signaling pathways that positively regulate functional β cell mass have not been full
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04627b273f5ee014c72a1e8bd7395618
https://pubmed.ncbi.nlm.nih.gov/24870561
https://pubmed.ncbi.nlm.nih.gov/24870561
Autor:
Maria L. Arbonés, Dulanjalee Kariyawasam, Nathalie Janel, Jean-Maurice Delabar, Virginie Aiello, Raphael Scharfmann, Michel Polak, Fanny Guez, Latif Rachdi
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
instname
Aims/hypothesis: Growth factors and nutrients are important regulators of pancreatic beta cell mass and function. However, the signalling pathways by which these factors modulate these processes have not yet been fully elucidated. DYRK1A (also named
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ac3aacaee28d6dcd62e28775dc7981e
https://pubmed.ncbi.nlm.nih.gov/24477974
https://pubmed.ncbi.nlm.nih.gov/24477974