Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Virginie Blot"'
Autor:
Momtez Jmai, Didier Dubreuil, Mohamed Lotfi Efrit, Jacques Lebreton, Virginie Blot, Hedi M'rabet
Publikováno v:
Phosphorus, Sulfur, and Silicon and the Related Elements. 196:978-995
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::598fecb1b28f6817e337f8b87cc304b2
https://doi.org/10.1080/10426507.2021.1948850
https://doi.org/10.1080/10426507.2021.1948850
Autor:
Arnaud Tessier, Jézabel Rocher, Katy Akoumany, Allan Patinec, Virginie Blot, Didier Dubreuil, Jacques Le Pendu, Jean-Yves Le Questel, Bruno Linclau, Samuel Golten, Jérôme Graton, Muriel Pipelier, Denis Jacquemin, J.Y. Douillard, Jacques Lebreton
Publikováno v:
European Journal of Medicinal Chemistry
European Journal of Medicinal Chemistry, Elsevier, 2019, 178, pp.195-213. ⟨10.1016/j.ejmech.2019.05.069⟩
European Journal of Medicinal Chemistry, Elsevier, 2019, 178, pp.195-213. ⟨10.1016/j.ejmech.2019.05.069⟩
20 iNKT cells recognize CD1d/-galactosylceramide (-GalCer) complexes via their invariant 21 TCR receptor and stimulate the immune response. Many -GalCer analogues have been 22 investigated to interrogate this interaction. Following our previ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e7b38d7d1fdee0ea28dfc8baaaa2f4f
https://pubmed.ncbi.nlm.nih.gov/31185411
https://pubmed.ncbi.nlm.nih.gov/31185411
Autor:
Barbara Wicher, Guillaume Lautrette, Virginie Blot, Jacques Lebreton, Muriel Pipelier, Ivan Huc, Didier Dubreuil, Maxime Horeau, Yann Ferrand
Publikováno v:
Angewandte Chemie
Angewandte Chemie, Wiley-VCH Verlag, 2017, 129 (24), pp.6927-6931. ⟨10.1002/ange.201701693⟩
Angewandte Chemie, Wiley-VCH Verlag, 2017, 129 (24), pp.6927-6931. ⟨10.1002/ange.201701693⟩
International audience; The development of foldamer-based receptors is driven by the design of monomers with specific properties. Herein, we introduce a pyridazine-pyridine-pyridazine diacid monomer and its incorporation into helical aromatic oligoam
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34cec28580b8d43e9813e56663155075
https://pubmed.ncbi.nlm.nih.gov/28471081
https://pubmed.ncbi.nlm.nih.gov/28471081
Autor:
Virginie Blot, Muriel Pipelier, Denis Jacquemin, Guillaume Viault, Didier Dubreuil, Anirban Kar, Ouassila Selaïmia-Ferdjani, Maxime Horeau, Xavier Guillory, Arnaud Tessier, Sambhaji P. Chavan, Jacky Pouessel, Aurélien Planchat
Publikováno v:
European Journal of Organic Chemistry. 2013:7083-7094
We have developed an efficient diastereoselective synthetic route towards a nardosinane sesquiterpene scaffold. The strategy used a key bicyclic diene intermediate 11a, and allowed access to valuable polyoxygenated sesquiterpenes 21 and 22, which may
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::38c72901a4a58aa8b21c2f37ad4ea5c8
https://doi.org/10.1002/ejoc.201301087
https://doi.org/10.1002/ejoc.201301087
Autor:
Karène Urgin, Sylvie Condon, Muriel Pipelier, Christine Thobie-Gautier, Christophe Aube, Virginie Blot, Stéphane Sengmany, Eric Léonel, Jacques Lebreton, Didier Dubreuil
Publikováno v:
European Journal of Organic Chemistry. 2013:117-124
The cross-coupling reactions of 3,6-dihalopyridazines with triaryl- or triheteroarylbismuth compounds were performed under palladium catalysis. The reaction was highly chemoselective, affording functionalized aryl- or heteroarylpyridazinyl chlorides
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d1190f1719db7a47036546ff12eb4479
https://doi.org/10.1002/ejoc.201200977
https://doi.org/10.1002/ejoc.201200977
Autor:
J.Y. Douillard, Christine Saluzzo, Stéphane Guillarme, Gilles Dujardin, Séverine Marionneau-Lambot, Jézabel Rocher, Jacques Le Pendu, Jean-Yves Le Questel, Michel Evain, Jacques Lebreton, Jean-Cédric Frison, Didier Dubreuil, Mette Diswall, Muriel Pipelier, Thibauld Oullier, Denis Jacquemin, Jérôme Graton, Julie Hunault, Virginie Blot
Publikováno v:
Journal of Medicinal Chemistry
Journal of Medicinal Chemistry, American Chemical Society, 2012, 55 (3), pp.1227-1241. ⟨10.1021/jm201368m⟩
Journal of Medicinal Chemistry, American Chemical Society, 2012, 55 (3), pp.1227-1241. ⟨10.1021/jm201368m⟩
We propose here the synthesis and biological evaluation of 3,4-dideoxy-GalCer derivatives. The absence of the 3- and 4-hydroxyls on the sphingoid base is combined with the introduction of mono or difluoro substituent at C3 (analogues 8 and 9, respect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f556f1ec2e2dbc55f525dbb4debb45f0
https://doi.org/10.1021/jm201368m
https://doi.org/10.1021/jm201368m
Autor:
Julie Hunault, Adjou Ané, Virginie Silvestre, Nathalie Bourgougnon, Jacques Lebreton, Raymond F. Schinazi, Muriel Pipelier, Jong-Hyun Cho, Mervi Detorio, Valérie Fargeas, Virginie Blot, Didier Dubreuil, Wilfried Hatton, Maxim Egorov, Christophe Len, Tami R. McBrayer
Publikováno v:
European Journal of Organic Chemistry
European Journal of Organic Chemistry, Wiley-VCH Verlag, 2011, 36, pp.7390-7399
European J Org Chem
European Journal of Organic Chemistry, Wiley-VCH Verlag, 2011, 36, pp.7390-7399
European J Org Chem
A set of pyrimidine nucleosides fused with a 4′-C,3′-O-propylene bridge was successfully synthesised in 12 steps from 1,2:5,6-di-O-isopropylidene-α-d-glucofuranose, an inexpensive starting material, based on a ring-closing metathesis (RCM) react
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27c86db0406f01a9c67f0953d7937b8d
https://doi.org/10.1002/ejoc.201100859
https://doi.org/10.1002/ejoc.201100859
Autor:
Virginie Blot, Julie Hunault, Jacques Le Pendu, Didier Dubreuil, Anne-Laure Turcot-Dubois, Laurent Micouin, Marc Bonneville, Vivien Lacone, Thomas Lecourt, Séverine Marionneau, Jézabelle Rocher, Muriel Pipelier, Monique Clément, J.Y. Douillard
Publikováno v:
Journal of Medicinal Chemistry. 52:4960-4963
4-Deoxy-alpha-GalCer analogues are considered weaker agonists than KRN7000 for the stimulation of human iNKT cells, but this remains strongly debated. In this work, we described a strategy toward 4-deoxy-alpha-GalCers with, as a key step, a metathesi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b422cb212bc920bca95b8dabbd45ffaa
https://doi.org/10.1021/jm900290r
https://doi.org/10.1021/jm900290r
Publikováno v:
Synthesis. 2009:759-766
Sphingosine-1-phosphate (S1P, 1) is a bioactive sphingolipid metabolite involved in a variety of critical cellular processes including proliferation, survival, and migration. For this reason the stereoselective syntheses of S1P and analogues are of g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5c692cc223204dd8dc0c72764d9c90ac
https://doi.org/10.1055/s-0028-1083373
https://doi.org/10.1055/s-0028-1083373
Autor:
Hans-Ulrich Reissig, Virginie Blot
Publikováno v:
European Journal of Organic Chemistry. 2006:4989-4992
Samarium diiodide promoted the intramolecular reductive couplings of N-alkylated indole and pyrrole derivatives 9–12 and 14 to afford products 15–19 that incorporate seven- and eight-membered rings. They were obtained in good yields and generally
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cc6e7c0cb34755eb1d5b89e63dac85a
https://doi.org/10.1002/ejoc.200600743
https://doi.org/10.1002/ejoc.200600743