Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Virginie, Tardif"'
Autor:
Julie Rondeaux, Déborah Groussard, Sylvanie Renet, Virginie Tardif, Anaïs Dumesnil, Alphonse Chu, Léa Di Maria, Théo Lemarcis, Manon Valet, Jean-Paul Henry, Zina Badji, Claire Vézier, Delphine Béziau-Gasnier, Annette E. Neele, Menno P. J. de Winther, Dominique Guerrot, Marjorie Brand, Vincent Richard, Eric Durand, Ebba Brakenhielm, Sylvain Fraineau
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract Epigenetic regulation of histone H3K27 methylation has recently emerged as a key step during alternative immunoregulatory M2-like macrophage polarization; known to impact cardiac repair after Myocardial Infarction (MI). We hypothesized that
Externí odkaz:
https://doaj.org/article/c73ad8d8e7874795be8b6aa46ecf3ac0
Autor:
Jennifer Connors, Gina Cusimano, Nathan Mege, Kyra Woloszczuk, Emily Konopka, Matthew Bell, David Joyner, Jennifer Marcy, Virginie Tardif, Michele A. Kutzler, Roshell Muir, Elias K. Haddad
Publikováno v:
Human Vaccines & Immunotherapeutics, Vol 19, Iss 3 (2023)
In the field of immunology, a systems biology approach is crucial to understanding the immune response to infection and vaccination considering the complex interplay between genetic, epigenetic, and environmental factors. Significant progress has bee
Externí odkaz:
https://doaj.org/article/c0f6d54dbefc41c98846e72a4e1051a7
Autor:
Hope Steele, Jason Cheng, Ashley Willicut, Garrison Dell, Joey Breckenridge, Erica Culberson, Andrew Ghastine, Virginie Tardif, Rana Herro
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Fibrosis is the result of extracellular matrix protein deposition and remains a leading cause of death in USA. Despite major advances in recent years, there remains an unmet need to develop therapeutic options that can effectively degrade or reverse
Externí odkaz:
https://doaj.org/article/588ed54f5a8a408ba61f7ca6b3b161f5
Autor:
Margaret H. O’Connor, Roshell Muir, Marita Chakhtoura, Michael Fang, Eirini Moysi, Susan Moir, Alison J. Carey, Alyssa Terk, Carmen N. Nichols, Talibah Metcalf, Constantinos Petrovas, Mark J. Cameron, Virginie Tardif, Elias K. Haddad
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-13 (2021)
Margaret O’Connor et al. report a new Innate Lymphoid Cell population in human tonsils and lymph nodes that inhibit the functional interaction of follicular helper T cells and germinal center B cells. They show that this cell population is expanded
Externí odkaz:
https://doaj.org/article/a866230b1fdc4b2fb508ecc62a24397c
Autor:
Virginie Tardif, Roshell Muir, Rafael Cubas, Marita Chakhtoura, Peter Wilkinson, Talibah Metcalf, Rana Herro, Elias K. Haddad
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
Follicular helper T cells are critical in the generation of the antibody response. Here the authors show that adenosine deaminase is involved in the Tfh program and ensuring the provision of B cell help.
Externí odkaz:
https://doaj.org/article/628425c3aec1481fb1851b02fede3b99
Autor:
Marita Chakhtoura, Mike Fang, Rafael Cubas, Margaret H O'Connor, Carmen N Nichols, Brian Richardson, Aarthi Talla, Susan Moir, Mark J Cameron, Virginie Tardif, Elias K Haddad
Publikováno v:
PLoS Pathogens, Vol 17, Iss 7, p e1009732 (2021)
We have recently demonstrated that the function of T follicular helper (Tfh) cells from lymph nodes (LN) of HIV-infected individuals is impaired. We found that these cells were unable to provide proper help to germinal center (GC)-B cells, as observe
Externí odkaz:
https://doaj.org/article/291573c3b8f04ece8dfdb7a54f6e1523
Autor:
Mouad Hamzaoui, Deborah Groussard, Dorian Nezam, Zoubir Djerada, Gaspard Lamy, Virginie Tardif, Anais Dumesnil, Sylvanie Renet, Valery Brunel, Dorien J.M. Peters, Laurence Chevalier, Mélanie Hanoy, Paul Mulder, Vincent Richard, Jeremy Bellien, Dominique Guerrot
Publikováno v:
Hypertension, 79(11), 2542-2551. LIPPINCOTT WILLIAMS & WILKINS
Background: Autosomal dominant polycystic kidney disease is the most frequent hereditary kidney disease and is generally due to mutations in PKD1 and PKD2 , encoding polycystins 1 and 2. In autosomal dominant polycystic kidney disease, hypertension a
Autor:
Coraline Heron, Anais Dumesnil, Mahmoud Houssari, Sylvanie Renet, Theo Lemarcis, Alexis Lebon, David Godefroy, Damien Schapman, Orianne Henri, Gaetan Riou, Lionel Nicol, Jean-Paul Henry, Manon Valet, Marie Pieronne-Deperrois, Antoine Ouvrard-Pascaud, Réné Hagerling, Hélène Chiavelli, Jean-Baptiste Michel, Paul Mulder, Sylvain Fraineau, Vincent Richard, Virginie Tardif, Ebba Brakenhielm
Publikováno v:
Cardiovascular Research. 119:492-505
Aims Lymphatics are essential for cardiac health, and insufficient lymphatic expansion (lymphangiogenesis) contributes to development of heart failure (HF) after myocardial infarction. However, the regulation and impact of lymphangiogenesis in non-is
Autor:
Alexandrine Mahoudeau, Céline Anquetil, Nozomu Tawara, Hossein Khademian, Damien Amelin, Loïs Bolko, Marco Silvestro, Julian Dal Cin, Bérénice Tendrel, Virginie Tardif, Kubéraka Mariampillai, Gillian Butler‐Browne, Olivier Benveniste, Yves Allenbach
Publikováno v:
Neuropathology and Applied Neurobiology
Neuropathology and Applied Neurobiology, 2022, ⟨10.1111/nan.12849⟩
Neuropathology and Applied Neurobiology, 2022, ⟨10.1111/nan.12849⟩
In idiopathic inflammatory myopathies (IIM), disease activity is difficult to assess, and IIM may induce severe muscle damage, especially in immune-mediated necrotising myopathies (IMNM) and inclusion body myositis (IBM). We hypothesise that myostati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a97a7c1f76187d67de805e99719abd55
https://hal.science/hal-03830849
https://hal.science/hal-03830849
Autor:
Susan Moir, Talibah Metcalf, Margaret H. O’Connor, Eirini Moysi, Marita Chakhtoura, Alison J. Carey, Virginie Tardif, Mike Fang, Constantinos Petrovas, Mark J. Cameron, Carmen N. Nichols, Alyssa R. Terk, Elias K. Haddad, Roshell Muir
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-13 (2021)
Innate Lymphoid Cells (ILCs) are immune cells typically found on mucosal surfaces and in secondary lymphoid organs where they regulate the immune response to pathogens. Despite their key role in the immune response, there are still fundamental gaps i