Výsledky vyhledávání - "Virginie, Berthet"

Inhibition of Proprotein Convertases Enhances Cell Migration and Metastases Development of Human Colon Carcinoma Cells in a Rat Model

Autor: Erik Bruyneel, Nabil G. Seidah, Jean-Yves Scoazec, Lionel Remy, Virginie Berthet, Jacques Marvaldi, Véronique Rigot, José Luis, Marie-France Jacquier, Sullivan Laforest, Mimoun Nejjari

Publikováno v: The American Journal of Pathology. 164:1925-1933

Although proprotein convertases are involved in tumor development, nothing is known about their role in metastatic dissemination. To investigate the involvement of convertase inhibition, we used human colon carcinoma cells overexpressing alpha1-antit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74cdc40e158dc9aa18d8d6f3f5042bfe
https://doi.org/10.1016/s0002-9440(10)63753-4

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Medulloblastoma cell invasion is inhibited by green tea (−)epigallocatechin-3-gallate

Autor: Anthony Pilorget, Richard Béliveau, José Luis, Virginie Berthet, Borhane Annabi, Albert Moghrabi

Publikováno v: Journal of Cellular Biochemistry. 90:745-755

Epigallocatechin-3-gallate (EGCG), the major green tea polyphenol, can reach the brain following oral intake and could thus act as an anti-tumoral agent targeting several key steps of brain cancer cells invasive activity. Because integrin-mediated ex

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f41bcbee14f6c6c4fe3c5e40390b82e1
https://doi.org/10.1002/jcb.10667

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Intracellular maturation and transport of tumor necrosis factor alpha converting enzyme

Autor: Franck Peiretti, Gilles Nalbone, Irène Juhan-Vague, Virginie Berthet, Paule Deprez-Beauclair, Matthias Canault, Bernadette Bonardo

Publikováno v: Experimental Cell Research. 285:278-285

The tumor necrosis factor alpha converting enzyme (TACE) activity is required for the shedding of a variety of biologically active membrane bound precursors. The activation of TACE necessitates the proteolytic cleavage of its prodomain, a process tha

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00120afb1fa1f85fae3d7a696b229960
https://doi.org/10.1016/s0014-4827(03)00052-1

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Lebectin, a novel C-type lectin from Macrovipera lebetina venom, inhibits integrin-mediated adhesion, migration and invasion of human tumour cells

Autor: Mohamed Elayeb, Jacques Marvaldi, Jeannine Secchi, José Luis, Juan J. Calvete, Virginie Berthet, Naziha Marrakchi, Sameh Sarray

Publikováno v: Laboratory Investigation
Laboratory Investigation, Nature Publishing Group, 2004, 84 (5), pp.573-81. ⟨10.1038/labinvest.3700088⟩

International audience; The adhesion receptors of the integrin family play an essential role during tumour progression and thus represent interesting potential targets for the development of new therapeutic agents. The snake venom contains natural in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2eb7482337f48de46307a6123bd6ea95
https://hal-riip.archives-ouvertes.fr/pasteur-00875524

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Medulloblastoma cell invasion is inhibited by green tea (-)epigallocatechin-3-gallate

Autor: Anthony, Pilorget, Virginie, Berthet, José, Luis, Albert, Moghrabi, Borhane, Annabi, Richard, Béliveau

Publikováno v: Journal of cellular biochemistry. 90(4)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::90822a3da9cef38dc9b25e2db56b56f3
https://pubmed.ncbi.nlm.nih.gov/14587030

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[Involvement of FAK, PI3-K and PKC in cell adhesion induced by microtubule disruption]

Autor: Azzeddine, Kadi, Virginie, Berthet, Véronique, Pichard, Brigitte, Abadie, Jean-Baptiste, Rognoni, Jacques, Marvaldi, José, Luis

Publikováno v: Bulletin du cancer. 89(2)

We have previously shown that microtubule disruption results in an increase in cell adhesion to ECM proteins. In this work we show that this enhanced cell attachment was completely abolished by specific inhibitors of tyrosine-kinases, PI3-K and PKCs.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::c60341814468b0787f8a4b3de31fb5cd
https://pubmed.ncbi.nlm.nih.gov/11888861

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Role of Endoproteolytic Processing in the Adhesive and Signaling Functions of αvβ5 Integrin

Autor: Virginie Berthet, Véronique Rigot, Serge Champion, Francis Fouchier, José Luis, Jacques Marvaldi, Jeannine Secchi

Publikováno v: Journal of Biological Chemistry
Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2000, 275 (43), pp.33308-33313. ⟨10.1074/jbc.M004834200⟩
Journal of Biological Chemistry, 2000, 275 (43), pp.33308-33313. ⟨10.1074/jbc.M004834200⟩

Some integrin alpha subunits undergo a post-translational cleavage in their extracellular domain. However, the role of this cleavage in integrin function is unclear. Enzymes involved in this maturation belong to the subtilisin-like endoprotease famil

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2026506a8705c98a7d59c740654e5f59
https://hal-amu.archives-ouvertes.fr/hal-03128135

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The endoproteolytic processing of αvβ5 integrin is involved in cytoskeleton remodelling and cell migration

Autor: Virginie Berthet, Mimoun Nejjari, Véronique Rigot, José Luis, Jacques Marvaldi

Publikováno v: FEBS Letters. (1-3):159-163

We previously showed that the post-translational cleavage of alphav subunit is essential for integrin-dependent signalling and cell adhesion. Here, we report that blocking alphav subunit cleavage by expression of alpha1-PDX, a convertase inhibitor, m

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