Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Virginia Van Keulen"'
Publikováno v:
The Journal of Immunology. 202:190.20-190.20
We hypothesize that B-lymphocytes are conducive to the pathogenesis of idiopathic pulmonary fibrosis (IPF), a progressive and fatal interstitial lung disease. B-lymphocytes aggregate in the lungs of IPF patients to form tertiary lymphoid follicles. H
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::65c5a145bd661361f5f0b2524931e181
https://doi.org/10.4049/jimmunol.202.supp.190.20
https://doi.org/10.4049/jimmunol.202.supp.190.20
Autor:
Adam Scheid, Virginia Van Keulen, Sara Felts, Yuji Zhang, Steven C Neier, Matthew Block, Svetomir Markovic, Aaron Mansfield, Larry R Pease
Publikováno v:
The Journal of Immunology. 196:124.60-124.60
In the context of immunity, genomic sequence, epigenetic, and environmental factor diversity combine to propagate variable gene expression and immune function among individuals. We hypothesize that we can harness gene expression variability across pe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d782beac439e75850381ac22ac2396f0
https://doi.org/10.4049/jimmunol.196.supp.124.60
https://doi.org/10.4049/jimmunol.196.supp.124.60
Publikováno v:
Advances in experimental medicine and biology. 750
Naturally occurring autoantibodies (NAbs) are common in normal humans. The majority of NAbs are IgMs, but a small proportion are IgGs. Therefore a certain portion of pooled whole human IgG (IVIG) can be considered NAbs. While the applications of IVIG
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::fbb5f908b27bf257f08848bda93c8aa6
https://pubmed.ncbi.nlm.nih.gov/22903665
https://pubmed.ncbi.nlm.nih.gov/22903665
Autor:
Xiaohua, Xu, Arthur E, Warrington, Brent R, Wright, Allan J, Bieber, Virginia, Van Keulen, Larry R, Pease, Moses, Rodriguez
Publikováno v:
Journal of neurochemistry. 119(1)
Mouse and human IgMs support neurite extension from primary cerebellar granule neurons. In this study using primary hippocampal and cortical neurons, we demonstrate that a recombinant human IgM, rHIgM12, promotes axon outgrowth by coupling membrane d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ae40cf7c6bdc5fea48e4100c06f70f3a
https://pubmed.ncbi.nlm.nih.gov/21824142
https://pubmed.ncbi.nlm.nih.gov/21824142
Publikováno v:
The Journal of Immunology. 194:60.6-60.6
To test the hypothesis that complex immune phenotypes can be defined by stable gene expression profiles we are using a RNAseq-based transcriptome analysis to relate phenotypes of activated peripheral blood CD4+ cells from healthy subjects and stage I
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ba8ad65f1e0c829b4c9bcc888d8c09bc
https://doi.org/10.4049/jimmunol.194.supp.60.6
https://doi.org/10.4049/jimmunol.194.supp.60.6
Autor:
Brendan Reed, Laura Chopp, Megan Girtman, Virginia Van Keulen, Aaron Johnson, Adam Schrum, Larry Pease
Publikováno v:
The Journal of Immunology. 192:69.27-69.27
MHC multimers including tetramers and pentamers provide a powerful way to visualize antigen specific T cell responses in both experimental and clinical immune assays. The multimers can be acquired commercially, from the NIH, or assembled in the labor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b65f631aeed5b85263a3cee8d6a1e513
https://doi.org/10.4049/jimmunol.192.supp.69.27
https://doi.org/10.4049/jimmunol.192.supp.69.27
Publikováno v:
The Journal of Immunology. 192:184.33-184.33
The complexity of molecular networks regulating the immune response presents challenges to measuring immune response potential in human populations. We measured gene expression in CD4+ peripheral blood cells from healthy subjects using RNAseq. RNA ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8dccc58e7bf2f421e90b89cebd41848f
https://doi.org/10.4049/jimmunol.192.supp.184.33
https://doi.org/10.4049/jimmunol.192.supp.184.33
Publikováno v:
The Journal of Immunology. 182:40.36-40.36
Background: Binding of the human IgM antibody B7-DC XAb to B7-DC on dendritic cells (DC) has profound immune modulatory effects. It enhances antigen presentation by DC, repolarizes T-helper (Th) 2 to Th1 cell responses, rapidly generates cytotoxic ef
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::002b84288366488691ce38558029543f
https://doi.org/10.4049/jimmunol.182.supp.40.36
https://doi.org/10.4049/jimmunol.182.supp.40.36