Zobrazeno 1 - 10
of 99
pro vyhledávání: '"Virginia Tzankova"'
Autor:
Iris C. Salaroglio, Denitsa Stefanova, Ricardo G. Teixeira, Nuno F.B. Oliveira, Amer Ahmed, Fabio Fusi, Virginia Tzankova, Yordan Yordanov, Miguel Machuqueiro, Simona Saponara, Andreia Valente, Chiara Riganti
Publikováno v:
Pharmacological Research, Vol 208, Iss , Pp 107353- (2024)
The therapeutic approach to many solid tumors, including non-small cell lung cancer (NSCLC), is mainly based on the use of platinum-containing anticancer agents and is often characterized by acquired or intrinsic resistance to the drug. Therefore, th
Externí odkaz:
https://doaj.org/article/2f88abcebe004d218abfc467fccfd25d
Autor:
Maya Georgieva, Emilio Mateev, Iva Valkova, Hristina Kuteva, Diana Tzankova, Denitsa Stefanova, Yordan Yordanov, Karolina Lybomirova, Alexander Zlatkov, Virginia Tzankova, Magdalena Kondeva-Burdina
Publikováno v:
Molecules, Vol 29, Iss 18, p 4338 (2024)
Neurodegenerative diseases such as Parkinson’s and Alzheimer’s continue to be some of the most significant challenges in modern medicine. Recent research related to the molecular mechanisms of parkinsonism has opened up new approaches to antipark
Externí odkaz:
https://doaj.org/article/318f754feb064a5385231eb3e75ce698
Autor:
Marta Slavkova, Diana Dimitrova, Christina Voycheva, Teodora Popova, Ivanka Spassova, Daniela Kovacheva, Yordan Yordanov, Virginia Tzankova, Borislav Tzankov
Publikováno v:
Gels, Vol 10, Iss 6, p 356 (2024)
Mesoporous silica nanoparticles (MSNs) are inorganic nanocarriers presenting versatile properties and the possibility to deliver drug molecules via different routes of application. Their modification with lipids could diminish the burst release profi
Externí odkaz:
https://doaj.org/article/3a536b5257a14fae949ce337ec0a1ca0
Autor:
Lyubomira Radeva, Yordan Yordanov, Ivanka Spassova, Daniela Kovacheva, Ivanka Pencheva-El Tibi, Maya M. Zaharieva, Mila Kaleva, Hristo Najdenski, Petar D. Petrov, Virginia Tzankova, Krassimira Yoncheva
Publikováno v:
Gels, Vol 10, Iss 5, p 346 (2024)
Resveratrol could be applied in wound healing therapies because of its antioxidant, anti-inflammatory and antibacterial effects. However, the main limitation of resveratrol is its low aqueous solubility. In this study, resveratrol was included in hyd
Externí odkaz:
https://doaj.org/article/e590fee3e87f4b298d3d42e0fffe47fc
Autor:
Emilio Mateev, Magdalena Kondeva-Burdina, Maya Georgieva, Alexandrina Mateeva, Iva Valkova, Virginia Tzankova, Alexander Zlatkov
Publikováno v:
Scientia Pharmaceutica, Vol 92, Iss 2, p 18 (2024)
Considering the complex pathogenesis of Alzheimer’s disease (AD), the multitarget ligand strategy is expected to provide superior effects for the treatment of the neurological disease compared to the classic single target approach. Thus, a series o
Externí odkaz:
https://doaj.org/article/d09fa31abe3f400596318366e54b4d5f
Autor:
Ivelina Ivanova, Marta Slavkova, Teodora Popova, Borislav Tzankov, Denitsa Stefanova, Virginia Tzankova, Diana Tzankova, Ivanka Spassova, Daniela Kovacheva, Christina Voycheva
Publikováno v:
Gels, Vol 10, Iss 3, p 165 (2024)
Agar, a naturally occurring polysaccharide, has been modified by grafting it with acrylic (AcA) and methacrylic (McA) acid monomers, resulting in acrylic or methacrylic acid grafted polymer (AA-g-AcA or AA-g-McA) with pH-sensitive swelling behavior.
Externí odkaz:
https://doaj.org/article/2f1bb6967d1842a5bb81c0b8160fba54
Autor:
Borislav Angelov, Emilio Mateev, Maya Georgieva, Virginia Tzankova, Magdalena Kondeva-Burdina
Publikováno v:
Pharmacia, Vol 69, Iss 4, Pp 1013-1017 (2022)
Four pyrrole based hydazide-hydrazones with established low hepatotoxicity and promising antiproliferative activity were evaluated (at 1µM concentration) for possible inhibitory activity on human isoforms of Cytochrome P450 CYP1A2, CYP3A4 and CYP2D6
Externí odkaz:
https://doaj.org/article/c66e130240f34ba1b8648d4c18ee54c3
Autor:
Marta Slavkova, Christophor Lazov, Ivanka Spassova, Daniela Kovacheva, Ivanka Pencheva-El Tibi, Denitsa Stefanova, Virginia Tzankova, Petar D. Petrov, Krassimira Yoncheva
Publikováno v:
Gels, Vol 10, Iss 1, p 79 (2024)
Budesonide is a mineral corticoid applied in the local therapy of pediatric atopic dermatitis. Unfortunately, its dermal administration is hindered by the concomitant adverse effects and its physicochemical properties. The characteristic pH change in
Externí odkaz:
https://doaj.org/article/385186e0651d4a3d81290ed3ca5e8acb
Autor:
Christina Voycheva, Marta Slavkova, Teodora Popova, Diana Tzankova, Denitsa Stefanova, Virginia Tzankova, Ivelina Ivanova, Stanislav Tzankov, Ivanka Spassova, Daniela Kovacheva, Borislav Tzankov
Publikováno v:
Gels, Vol 9, Iss 9, p 769 (2023)
Hydrogels can offer many opportunities for drug delivery strategies. They can be used on their own, or their benefits can be further exploited in combination with other nanocarriers. Intelligent hydrogels that react to changes in the surrounding envi
Externí odkaz:
https://doaj.org/article/701630c73f4c4dcd924323cbf84641c5
Autor:
Diana Tzankova, Hristina Kuteva, Emilio Mateev, Denitsa Stefanova, Alime Dzhemadan, Yordan Yordanov, Alexandrina Mateeva, Virginia Tzankova, Magdalena Kondeva-Burdina, Alexander Zlatkov, Maya Georgieva
Publikováno v:
Pharmaceuticals, Vol 16, Iss 9, p 1198 (2023)
A series of ten new hydrazide–hydrazone derivatives bearing a pyrrole ring were synthesized and structurally elucidated through appropriate spectral characteristics. The target hydrazones were assessed for radical scavenging activity through 1,1-di
Externí odkaz:
https://doaj.org/article/ea4674433cea4832b4457cacc302e0ac