Zobrazeno 1 - 10
of 75
pro vyhledávání: '"Virginia P. Winfrey"'
Publikováno v:
PLoS ONE, Vol 9, Iss 7, p e103486 (2014)
Selenium is transferred from the mouse dam to its neonate via milk. Milk contains selenium in selenoprotein form as selenoprotein P (Sepp1) and glutathione peroxidase-3 (Gpx3) as well as in non-specific protein form as selenomethionine. Selenium is a
Externí odkaz:
https://doaj.org/article/78892e46c4db4f25961de854d887c45c
Autor:
Kristina E. Hill, Suguru Kurokawa, Gary E. Olson, Virginia P. Winfrey, Raymond F. Burk, Amy K. Motley
Publikováno v:
The FASEB Journal. 27:3249-3256
Selenoprotein P (Sepp1) is taken up by receptor-mediated endocytosis for its selenium. The other extracellular selenoprotein, glutathione peroxidase-3 (Gpx3), has not been shown to transport selenium. Mice with genetic alterations of Sepp1, the Sepp1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9908a1f63c57a972a6685edde469b8f
https://doi.org/10.1096/fj.13-231852
https://doi.org/10.1096/fj.13-231852
Publikováno v:
The international journal of biochemistrycell biology. 80
Nevertheless, a nonviable sperm population is present in the cauda epididymidis of many species. Degenerating spermatozoa release enzymes that could have detrimental effects on the viability of neighboring cells, and they are source of autoantigens t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::360782b525dd5ba48267b5268fa02712
https://pubmed.ncbi.nlm.nih.gov/27732889
https://pubmed.ncbi.nlm.nih.gov/27732889
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology. 301:G32-G38
Glutathione peroxidase-3 (Gpx3), the extracellular glutathione peroxidase synthesized largely in the kidney, binds to basement membranes of renal cortical epithelial cells. The present study assessed extrarenal expression of Gpx3 using RT-PCR and pre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de659e52111085f7b2e96c97088821a8
https://doi.org/10.1152/ajpgi.00064.2011
https://doi.org/10.1152/ajpgi.00064.2011
Publikováno v:
Proceedings of the National Academy of Sciences. 104:19843-19848
Cilia project from cells as membranous extensions, with microtubule structural cores assembling from basal bodies by intraflagellar transport (IFT). Here, we report a ciliary role for the inositol 1,3,4,5,6-pentakisphosphate 2-kinase (Ipk1) that gene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1466a8ddaffca2adc0a7d458e7fb0ae6
https://doi.org/10.1073/pnas.0706934104
https://doi.org/10.1073/pnas.0706934104
Publikováno v:
Journal of Biological Chemistry. 282:12290-12297
Selenium is a micronutrient that is essential for the production of normal spermatozoa. The selenium-rich plasma protein selenoprotein P (Sepp1) is required for maintenance of testis selenium and for fertility of the male mouse. Sepp1 trafficking in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71964e48091f3b4878d9731fcfe26c79
https://doi.org/10.1074/jbc.m611403200
https://doi.org/10.1074/jbc.m611403200
Autor:
Gary E. Olson, Michael H. Melner, Arthur L. Haas, Alan R. Brash, Jennifer M. Klein, Virginia P. Winfrey, Subir K. Nagdas, William E. Boeglin
Publikováno v:
Biology of Reproduction. 75:395-406
We recently identified a differentially expressed gene in implantation stage rabbit endometrium encoding a new member of the ubiquitin-conjugating enzyme family designated UBE2Q2 (also known as UBCi). Its unusually high molecular mass, novel N-termin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c917300929737186236cd005754bebc0
https://doi.org/10.1095/biolreprod.106.051458
https://doi.org/10.1095/biolreprod.106.051458
Publikováno v:
Biology of Reproduction. 75:197-202
Sperm mitochondria undergo remodeling during posttesticular maturation that includes extensive disulfide cross-linking of proteins of the outer membrane to form the insoluble mitochondrial capsule. The relationship of these changes to mitochondrial f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ff37dbcbfa045e7304a089df34a46cd2
https://doi.org/10.1095/biolreprod.106.051375
https://doi.org/10.1095/biolreprod.106.051375
Publikováno v:
Biology of Reproduction. 73:201-211
Selenoprotein P (SEPP1), an extracellular glycoprotein of unknown function, is a unique member of the selenoprotein family that, depending on species, contains 10–17 selenocysteines in its primary structure; in contrast, all other family members co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b9eb02778b8f15320d3d8032a66491f9
https://doi.org/10.1095/biolreprod.105.040360
https://doi.org/10.1095/biolreprod.105.040360
Publikováno v:
Biology of Reproduction. 72:164-171
Sperm capacitation is a maturation process, occurring in the female reproductive tract, that produces fertilization-competent spermatozoa. Protein tyrosine phosphorylation represents an important event in capacitation. The present study demonstrates
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d1e3158dd59cd0b27b8bfc06f02d8b0b
https://doi.org/10.1095/biolreprod.104.033530
https://doi.org/10.1095/biolreprod.104.033530