Zobrazeno 1 - 10
of 132
pro vyhledávání: '"Virginia Merino"'
Autor:
Carlos Tamarit-Martínez, Lucía Bernat-Just, Carlos Bueno-López, Adrián M. Alambiaga-Caravaca, Virginia Merino, Alicia López-Castellano, Vicent Rodilla
Publikováno v:
Pharmaceutics, Vol 16, Iss 9, p 1151 (2024)
Infections are one of the main complications in arthroplasties. These infections are difficult to treat because the bacteria responsible for them settle in the prosthesis and form a biofilm that does not allow antimicrobials to reach the infected are
Externí odkaz:
https://doaj.org/article/7de6201d53424ba0b60106a2a89d3f1c
Autor:
Andreu Mañez-Asensi, Mª Jesús Hernández, Víctor Mangas-Sanjuán, Ana Salvador, Matilde Merino-Sanjuán, Virginia Merino
Publikováno v:
Pharmaceutics, Vol 16, Iss 6, p 749 (2024)
The demonstration of bioequivalence proposed in the European Medicines Agency’s (EMA’s) draft guideline for topical products with the same qualitative and quantitative composition requires the confirmation of the internal structure equivalence. T
Externí odkaz:
https://doaj.org/article/97d15faa0ae34de4b5a15a4db6904e23
Autor:
Gema J. Cabañero-Resta, Bárbara Sánchez-Dengra, Alejandro Ruiz-Picazo, Marival Bermejo, Virginia Merino, Isabel Gonzalez-Alvarez, Marta Gonzalez-Alvarez
Publikováno v:
Pharmaceutics, Vol 16, Iss 5, p 576 (2024)
Itraconazole is a drug used in veterinary medicine for the treatment of different varieties of dermatophytosis at doses between 3–5 mg/kg/day in cats. Nevertheless, in Spain, it is only available in the market as a 52 mL suspension at 10 mg/mL. The
Externí odkaz:
https://doaj.org/article/00451bfc92f04f01a61da5add29a91de
Autor:
Isabel Gonzalez-Alvarez, Alejandro Ruiz-Picazo, Ruben Selles-Talavera, Andres Figueroa-Campos, Virginia Merino, Marival Bermejo, Marta Gonzalez-Alvarez
Publikováno v:
Pharmaceutics, Vol 16, Iss 3, p 390 (2024)
The purpose of this study was to predict the in vivo bioequivalence (BE) outcome of valsartan (VALS, BCS class IV) from three oral-fixed combination products with hydrochlorothiazide (HCTZ, BCS class III) (Co-Diovan® Forte as reference and two gener
Externí odkaz:
https://doaj.org/article/da117dad3d8f4fb28eb64ecc2b9cbb53
Publikováno v:
Pharmaceutics, Vol 15, Iss 2, p 601 (2023)
The development of second-entry topical products is hampered by several factors. The excipient composition should be similar to the reference product because excipients may also contribute to efficacy. Conventional pharmacokinetic bioequivalence stud
Externí odkaz:
https://doaj.org/article/52a4d5d5634d499cb5aa518a28c6be29
Autor:
Valeria Gigante, Giovanni M. Pauletti, Sabine Kopp, Minghze Xu, Isabel Gonzalez-Alvarez, Virginia Merino, Michelle P. McIntosh, Anita Wessels, Beom-Jin Lee, Kênnia Rocha Rezende, Gerhard K.E. Scriba, Gaurav P. S. Jadaun, Marival Bermejo
Publikováno v:
ADMET and DMPK (2020)
The WHO Biopharmaceutical Classification System (BCS) is a practical tool to identify active pharmaceutical ingredients (APIs) that scientifically qualify for a waiver of in vivo bioequivalence studies. The focus of this study was to engage a global
Externí odkaz:
https://doaj.org/article/5208c09f597b4583abb12e3bc52f96ba
Autor:
Carlos Bueno-López, Carlos Tamarit-Martínez, Adrián M. Alambiaga-Caravaca, Cristina Balaguer-Fernández, Virginia Merino, Alicia López-Castellano, Vicent Rodilla
Publikováno v:
Pharmaceuticals, Vol 14, Iss 12, p 1240 (2021)
In recent years, the use of 3D printing technologies in orthopedic surgery has markedly increased, as they offer the possibility of printing personalized prostheses. The work presented in this article is a preliminary study of a research project whic
Externí odkaz:
https://doaj.org/article/66355807705d45eaa4a6b76339c4d263
Autor:
Zhengguo Xu, Víctor Mangas-Sanjuán, Matilde Merino-Sanjuán, Virginia Merino, Alfredo García-Arieta
Publikováno v:
Pharmaceutics, Vol 12, Iss 12, p 1159 (2020)
Inter- and intra-batch variability of the quality attributes contribute to the uncertainty for demonstrating equivalent microstructure of post-approval changes and generic/hybrids of semisolid topical products. Selecting a representative sample size
Externí odkaz:
https://doaj.org/article/8ca0157ad3fc4a6d8aa85c14eb368367
Autor:
Adrian H. Teruel, Isabel Gonzalez-Alvarez, Marival Bermejo, Virginia Merino, Maria Dolores Marcos, Felix Sancenon, Marta Gonzalez-Alvarez, Ramon Martinez-Mañez
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 18, p 6502 (2020)
Colonic Drug Delivery Systems (CDDS) are especially advantageous for local treatment of inflammatory bowel diseases (IBD). Site-targeted drug release allows to obtain a high drug concentration in injured tissues and less systemic adverse effects, as
Externí odkaz:
https://doaj.org/article/bc156026543143e989859d744607fa46
Autor:
Andrés Figueroa-Campos, Bárbara Sánchez-Dengra, Virginia Merino, Arik Dahan, Isabel González-Álvarez, Alfredo García-Arieta, Marta González-Álvarez, Marival Bermejo
Publikováno v:
Pharmaceutics, Vol 12, Iss 7, p 633 (2020)
The main objective of this investigation was to develop an in vitro–in vivo correlation (IVIVC) for immediate release candesartan cilexetil formulations by designing an in vitro dissolution test to be used as development tool. The IVIVC could be us
Externí odkaz:
https://doaj.org/article/645b2d48b927437397ac2921d4809d20