Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Virginia M. Tennyson"'
Publikováno v:
Developmental Dynamics. 211:269-291
Megacolon occurs in neonatal and adult transgenic mice that overexpress the Hoxa-4 gene. Abnormalities, which are restricted to the terminal colon of these mice, include a hypoganglionosis, abnormal enteric ganglia with a structure appropriate for ex
Autor:
Maura C. Kibbey, Michael D. Gershon, Alcmène Chalazonitis, Virginia M. Tennyson, Taube P. Rothman
Publikováno v:
Journal of Neurobiology. 33:118-138
A plasmalemmal protein, LBP110, which binds to the α1 chain of laminin-1, is acquired by the neural crest-derived precursors of enteric neurons after they colonize the gut. We tested the hypothesis that laminin-1 interacts with LBP110 to promote ent
Autor:
Virginia M. Tennyson, Tuan Duc Pham, E. Blaugrund, Michael D. Gershon, L. Lo, D.J. Anderson, Lukas Sommer
Publikováno v:
Development. 122:309-320
Enteric and sympathetic neurons have previously been proposed to be lineally related. We present independent lines of evidence that suggest that enteric neurons arise from at least two lineages, only one of which expresses markers in common with symp
Autor:
Neil R. Smalheiser, Howard D. Pomeranz, Michael D. Gershon, Virginia M. Tennyson, Diane Sherman
Publikováno v:
The Journal of Comparative Neurology. 313:625-642
In order to give rise to the enteric nervous system (ENS), cells migrating from the neural crest must find the bowel and cease migrating at appropriate locations within the gut. Previous studies of the development of the ENS in a mutant mouse have le
Publikováno v:
The Journal of Comparative Neurology. 291:345-362
The terminal colon of the ls/ls mouse is aganglionic because an intrinsic defect prevents its colonization by cells migrating from the neural crest. Previous studies showed that laminin, type IV collagen, and glycosaminoglycans accumulate in the regi
Autor:
Richard R. Behringer, Michael D. Gershon, Regina Raz, Virginia M. Tennyson, David Crotty, Diane Sherman, Debra J. Wolgemuth
Publikováno v:
Developmental dynamics : an official publication of the American Association of Anatomists. 198(1)
Congenital megacolon develops in transgenic mice that overexpress the homeobox-containing gene, Hoxa-4. The current study was done to identify abnormalities of the terminal colon that might account for the phenotype. The terminal bowel of transgenic
Autor:
Michael D. Gershon, Taube P. Rothman, Alcmène Chalazonitis, Howard D. Pomeranz, Virginia M. Tennyson
Publikováno v:
Developmental biology. 156(2)
The neural crest-derived cells that colonize the bowel are different from their predecessors in the premigratory crest. A procedure, which utilized the immunoselection of cells with a magnet, was thus devised to obtain crest-derived precursors from d
Autor:
Debra J. Wolgemuth, Ralph L. Brinster, Richard D. Palmiter, Virginia M. Tennyson, Richard R. Behringer, David Crotty
Publikováno v:
Development (Cambridge, England). 117(3)
The murine homeobox-containing gene Hox-1.4 is expressed in restricted patterns during embryogenesis and in male germ cells. To begin identification of the cis-acting elements regulating this expression, transgenic mice were generated carrying a chim
Publikováno v:
Journal of the Neurological Sciences. 25:309-332
We have studied extrajunctional muscle of control and dystrophic mice by electron microscopic-cytochemistry and radiometric assay. We have found both a soluble and particulate AChE activity, which is similar proportionally in control and dystrophic m
Publikováno v:
Annals of the New York Academy of Sciences. 377:786-804
The therapeutic value of thymectomy for myasthenia is still questioned although it retains an important place among management modalities that strive for sustained remission. Questions derive from uncertainty as to appropriate timing, variable extent