Zobrazeno 1 - 10
of 136
pro vyhledávání: '"Virginia M Sanders"'
Autor:
Melissa M Haulcomb, Rena M Meadows, Whitney M Miller, Kathryn P McMillan, MeKenzie J Hilsmeyer, Xuefu Wang, Wesley T Beaulieu, Stephanie L Dickinson, Todd J Brown, Virginia M Sanders, Kathryn J Jones
Publikováno v:
Neural Regeneration Research, Vol 12, Iss 10, Pp 1664-1679 (2017)
Amyotrophic lateral sclerosis is a motoneuron degenerative disease that is challenging to diagnose and presents with considerable variability in survival. Early identification and enhanced understanding of symptomatic patterns could aid in diagnosis
Externí odkaz:
https://doaj.org/article/b04a1782a8fc44b6b41fcc1c3a0ff7f6
Autor:
Derek A Wainwright, Junping Xin, Nichole A Mesnard, Taylor R Beahrs, Christine M Politis, Virginia M Sanders, Kathryn J Jones
Publikováno v:
ASN Neuro, Vol 1 (2009)
We have previously demonstrated a neuroprotective mechanism of FMN (facial motoneuron) survival after facial nerve axotomy that is dependent on CD4 + Th2 cell interaction with peripheral antigen-presenting cells, as well as CNS (central nervous syste
Externí odkaz:
https://doaj.org/article/16a9610410a1434b86c5988385041b20
Autor:
Elizabeth M. Runge, Abhirami K. Iyer, Deborah O. Setter, Felicia M. Kennedy, Virginia M. Sanders, Kathryn J. Jones
Publikováno v:
Journal of Neuroinflammation, Vol 17, Iss 1, Pp 1-16 (2020)
Abstract Background After peripheral nerve transection, facial motoneuron (FMN) survival depends on an intact CD4+ T cell population and a central source of interleukin-10 (IL-10). However, it has not been determined previously whether CD4+ T cells p
Externí odkaz:
https://doaj.org/article/bcba5145ac1344cdb3a7d5b724311aaf
Autor:
Elizabeth M. Runge, Deborah O. Setter, Abhirami K. Iyer, Eric J. Regele, Felicia M. Kennedy, Virginia M. Sanders, Kathryn J. Jones
Publikováno v:
Cells, Vol 11, Iss 19, p 3167 (2022)
Facial motoneuron (FMN) survival is mediated by CD4+ T cells in an interleukin-10 (IL-10)-dependent manner after facial nerve axotomy (FNA), but CD4+ T cells themselves are not the source of this neuroprotective IL-10. The aims of this study were to
Externí odkaz:
https://doaj.org/article/43b57b1dd9e84abb8cbbc99bf2a90fae
Autor:
Taylor Beahrs, Virginia M. Sanders, Sara K. Custer, Nicole D. Schartz, Deborah O. Setter, Melissa M. Haulcomb, Rena M. Meadows, Kathryn J. Jones
Publikováno v:
Restorative Neurology and Neuroscience. 36:417-422
BACKGROUND When nerve transection is performed on adult rodents, a substantial population of neurons survives short-term disconnection from target, and the immune system supports this neuronal survival, however long-term survival remains unknown. Und
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b711f74e76f63c497eefd44ed9f3f81a
https://doi.org/10.3233/rnn-170809
https://doi.org/10.3233/rnn-170809
Autor:
Elizabeth M. Runge, Kathryn J. Jones, Felicia M. Kennedy, Virginia M. Sanders, Eric J. Regele
Publikováno v:
Proceedings of IMPRS. 1
Background and Hypothesis: It is unknown how the immune system maintains the majority of facial motoneuron (FMN) survival after axotomy. IL-10 cytokine is necessary for FMN survival and CD4+ T cells are activated and play a critical role in survival,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f997ebbca778f67d3f8ca6946fcdafc1
https://doi.org/10.18060/22748
https://doi.org/10.18060/22748
Autor:
Tao Yang, Allen Ni, Eileen M. Foecking, Kathryn J. Jones, Evan B. Stubbs Jr., Junping Xin, Virginia M. Sanders, Rafael Gutierrez, Nichole A. Mesnard-Hoaglin, Susan O. McGuire
Publikováno v:
Mediators of Inflammation. 2016:1-7
An increased risk of ALS has been reported for veterans, varsity athletes, and professional football players. The mechanism underlying the increased risk in these populations has not been identified; however, it has been proposed that motor nerve inj
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::359ee305a3fdfbef2e3d9e568dca682a
https://doi.org/10.1155/2016/6131234
https://doi.org/10.1155/2016/6131234
Publikováno v:
International Journal of Molecular Sciences, Vol 19, Iss 2, p 631 (2018)
International Journal of Molecular Sciences
International Journal of Molecular Sciences
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder characterized by progressive loss of lower and upper motor neurons (MN) leading to muscle weakness, paralysis and eventually death. Although a highly varied etiology results in ALS,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0abfafd447d36adadd877dd019239914
http://www.mdpi.com/1422-0067/19/2/631
http://www.mdpi.com/1422-0067/19/2/631
Autor:
Virginia M. Sanders, Nichole A. Mesnard-Hoaglin, Rena M. Meadows, Melissa M. Haulcomb, Kathryn J. Jones, Kathryn P. Mcmillan, Whitney M. Miller, Richard J. Batka, Todd J. Brown
Publikováno v:
Journal of Comparative Neurology. 523:2752-2768
Disease progression rates among patients with amyotrophic lateral sclerosis (ALS) vary greatly. Although the majority of affected individuals survive 3–5 years following diagnosis, some subgroups experience a more rapidly progressing form, survivin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::490c8156bb7bf1b5f4ee58cdffa56f61
https://doi.org/10.1002/cne.23814
https://doi.org/10.1002/cne.23814
Autor:
Karthryn J. Jones, Nicole D. Schartz, Virginia M. Sanders, Whitney M. Miller, Kathryn P. McMillan, Melissa M. Haulcomb, Kishan M. Shah, Elizabeth M. Runge, Deborah O. Setter, Brandon L. Brown, Felicia M. Kennedy
When facial nerve axotomy (FNA) is performed on immunodeficient recombinase activating gene-2 knockout (RAG-2−/−) mice, there is greater facial motoneuron (FMN) death relative to wild type (WT) mice. Reconstituting RAG-2−/− mice with whole sp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb1d739fdc4876a358a7e0d3ba8bf612
https://europepmc.org/articles/PMC5767532/
https://europepmc.org/articles/PMC5767532/
