Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Virginia L. Bertness"'
Autor:
Shai Izraeli, Michael R. Kuehn, Stefano Campaner, Ilan R. Kirsch, Linda A. Lowe, Heidi Hahn, Virginia L. Bertness
Publikováno v:
genesis. 31:72-77
Summary: The Sil gene encodes a cytosolic protein required for mouse embryonic midline and left/right axial development. Based on the phenotype of Sil mutant embryos, we hypothesized that Sil may be required for the activity of Sonic Hedgehog (Shh),
Autor:
Linda A. Lowe, Ilan R. Kirsch, Shai Izraeli, Michael R. Kuehn, Deborah J. Good, David W. Dorward, Virginia L. Bertness
Publikováno v:
Nature. 399:691-694
The establishment of the main body axis and the determination of left–right asymmetry are fundamental aspects of vertebrate embryonic development. A link between these processes has been revealed by the frequent finding of midline defects in humans
Autor:
Peter D. Aplan, Jeffrey Cossman, Virginia L. Bertness, Donald P. Lombardi, Ilan R. Kirsch, Ann M. Ginsberg
Publikováno v:
Science (New York, N.Y.). 250(4986)
A fusion complementary DNA in the T cell line HSB-2 elucidates a provocative mechanism for the disruption of the putative hematopoietic transcription factor SCL. The fusion cDNA results from an interstitial deletion between a previously unknown locus
Autor:
Avery A. Sandberg, Ilan R. Kirsch, Stephen D. Smith, Virginia L. Bertness, O. Wesley McBride, Rodman Morgan, Carolyn A. Felix
Publikováno v:
Cancer genetics and cytogenetics. 44(1)
The leukemic cells and derivative cell line from a 74-year-old male with T-cell acute lymphoblastic leukemia showed chromosomal abnormalities including a t(14;14)(q11.2;q32). This translocation is characteristic of a variety of T-cell malignancies, p
Publikováno v:
New England Journal of Medicine. 313:534-538
The ability to detect immunoglobulin-gene rearrangements has proved useful in confirming diagnoses of suspected B-cell lymphomas and in establishing their monoclonality. By analogy, we employed a cloned DNA probe for the beta chain of the T-cell rece
Autor:
James F. Battey, Ilan R. Kirsch, O. Wesley McBride, Virginia L. Bertness, Anne Marie Lebacq-Verheyden, Gregory F. Hollis
Publikováno v:
Somatic Cell and Molecular Genetics. 13:81-86
A complementary DNA clone encoding human pre-pro gastrin-releasing peptide, a 27-amino acid neuropeptide and putative growth factor, was used to determine the chromosomal location of this gene. Southern blot hybridization to genomic DNA isolated from
Autor:
Michael P. Davey, Ilan R. Kirsch, Thomas A. Waldmann, O. W. Mcbride, Kenneth Nakahara, J P Johnson, Virginia L. Bertness
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 85(23)
We describe a t(14;14)(q11;q32) translocation in a patient with T-cell chronic lymphocytic leukemia and ataxia-telangiectasia (AT). By using a battery of joining (J)-segment probes from the T-cell receptor (TCR) alpha-chain locus TCRA, three distinct
Autor:
Gregory F. Hollis, Ilan R. Kirsch, Joel H. Shaper, Nancy L. Shaper, Virginia L. Bertness, H. Chang
Publikováno v:
Somatic cell and molecular genetics. 12(6)
The structural gene for galactosyltransferase (glycoprotein 4-B-galactosyltransferase, EC 2.4.1.38) was localized to human chromosome 9 band p13 by chromosome in situ hybridization using a cloned bovine galactosyltransferase cDNA probe. This chromoso
Publikováno v:
Journal of cellular biochemistry. 32(1)
We have investigated the expression of the genes c-myb, c-myc, and alpha globin in murine erythroid cells at different stages of development, in viral-induced erythroleukemias, as well as in two mouse erythroleukemia cell lines that can be induced to
Autor:
Burke J. Brooks, Ilan R. Kirsch, Virginia L. Bertness, James F. Battey, Edward A. Sausville, John D. Minna, O. Wesley McBride, Marion M. Nau, Gregory F. Hollis, Adi F. Gazdar
Publikováno v:
Nature. 318(6041)
Altered structure and regulation of the c-myc proto-oncogene have been associated with a variety of human tumours and derivative cell lines, including Burkitt's lymphoma, promyelocytic leukaemia and small cell lung cancer (SCLC). The N-myc gene, firs