Zobrazeno 1 - 10
of 144
pro vyhledávání: '"Virginia L, Miller"'
Autor:
Olga G. Ovchinnikova, Logan P. Treat, Tanisha Teelucksingh, Bradley R. Clarke, Taryn A. Miner, Chris Whitfield, Kimberly A. Walker, Virginia L. Miller
Publikováno v:
mBio, Vol 14, Iss 3 (2023)
ABSTRACT Klebsiella pneumoniae is a leading cause of nosocomial infections, including pneumonia, bacteremia, and urinary tract infections. Treatment options are increasingly restricted by the high prevalence of resistance to frontline antibiotics, in
Externí odkaz:
https://doaj.org/article/8357e1b51d36462e839941a564b8e951
Publikováno v:
mBio, Vol 11, Iss 5 (2020)
ABSTRACT Klebsiella pneumoniae has a remarkable ability to cause a wide range of human diseases. It is divided into two broad classes: classical strains that are a notable problem in health care settings due to multidrug resistance, and hypervirulent
Externí odkaz:
https://doaj.org/article/209942c105344f6e8186e47308c3054c
Autor:
Kimberly A. Walker, Taryn A. Miner, Michelle Palacios, Dominika Trzilova, Daniel R. Frederick, Christopher A. Broberg, Victoria E. Sepúlveda, Joshua D. Quinn, Virginia L. Miller
Publikováno v:
mBio, Vol 10, Iss 2 (2019)
ABSTRACT The polysaccharide capsule is an essential virulence factor for Klebsiella pneumoniae in both community-acquired hypervirulent strains as well as health care-associated classical strains that are posing significant challenges due to multidru
Externí odkaz:
https://doaj.org/article/d253aa4c055244b39986388f75d67fdc
Autor:
W. Ryan Will, Peter Brzovic, Isolde Le Trong, Ronald E. Stenkamp, Matthew B. Lawrenz, Joyce E. Karlinsey, William W. Navarre, Kara Main-Hester, Virginia L. Miller, Stephen J. Libby, Ferric C. Fang
Publikováno v:
mBio, Vol 10, Iss 2 (2019)
ABSTRACT Gene duplication and subsequent evolutionary divergence have allowed conserved proteins to develop unique roles. The MarR family of transcription factors (TFs) has undergone extensive duplication and diversification in bacteria, where they a
Externí odkaz:
https://doaj.org/article/6e89773f3ee944aa996a1cf09ab4bf04
Autor:
Michelle Palacios, Taryn A. Miner, Daniel R. Frederick, Victoria E. Sepulveda, Joshua D. Quinn, Kimberly A. Walker, Virginia L. Miller
Publikováno v:
mBio, Vol 9, Iss 4 (2018)
ABSTRACT Klebsiella pneumoniae is widely recognized as a pathogen with a propensity for acquiring antibiotic resistance. It is capable of causing a range of hospital-acquired infections (urinary tract infections [UTI], pneumonia, sepsis) and communit
Externí odkaz:
https://doaj.org/article/f39045d829a44c37afed7e39105cd7c3
Publikováno v:
mSphere, Vol 2, Iss 4 (2017)
ABSTRACT Klebsiella pneumoniae is considered a significant public health threat because of the emergence of multidrug-resistant strains and the challenge associated with treating life-threatening infections. Capsule, siderophores, and adhesins have b
Externí odkaz:
https://doaj.org/article/14e5a52960df4e759eee08393712b382
Autor:
Roger D. Pechous, Christopher A. Broberg, Nikolas M. Stasulli, Virginia L. Miller, William E. Goldman
Publikováno v:
mBio, Vol 6, Iss 1 (2015)
ABSTRACT Inhalation of Yersinia pestis results in primary pneumonic plague, a highly lethal and rapidly progressing necrotizing pneumonia. The disease begins with a period of extensive bacterial replication in the absence of disease symptoms, followe
Externí odkaz:
https://doaj.org/article/787cf14f7c644f0eb875b5772cf524c4
Publikováno v:
PLoS Pathogens, Vol 11, Iss 1, p e1004587 (2015)
The series of events that occurs immediately after pathogen entrance into the body is largely speculative. Key aspects of these events are pathogen dissemination and pathogen interactions with the immune response as the invader moves into deeper tiss
Externí odkaz:
https://doaj.org/article/f9dc49c059dd4289b3d83d2e57713672
Publikováno v:
Journal of Bacteriology. 203
The Yersinia pestis pH 6 antigen (PsaA) forms fimbria-like structures and is required for full virulence during bubonic plague. High temperature and low pH regulate PsaA production, and while recent work has uncovered the molecular aspects of tempera
Publikováno v:
Journal of Bacteriology
The Yersinia pestis pH 6 antigen (PsaA) forms fimbria-like structures and is required for full virulence during bubonic plague. High temperature and low pH regulate PsaA production, and while recent work has uncovered the molecular aspects of tempera