Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Virginia L, Johnsen"'
Autor:
Chelsea L Deschamps, Kimberly E Connors, Matthias S Klein, Virginia L Johnsen, Jane Shearer, Hans J Vogel, Joseph M Devaney, Heather Gordish-Dressman, Gina M Many, Whitney Barfield, Eric P Hoffman, William E Kraus, Dustin S Hittel
Publikováno v:
PLoS ONE, Vol 10, Iss 6, p e0130644 (2015)
Homozygosity for a premature stop codon (X) in the ACTN3 "sprinter" gene is common in humans despite the fact that it reduces muscle size, strength and power. Because of the close relationship between skeletal muscle function and cardiometabolic heal
Externí odkaz:
https://doaj.org/article/6a8c4452e9f34899a8c9c75345a2f593
Autor:
Jane Shearer, Virginia L. Johnsen, Matthias S. Klein, Christopher Newell, Aneal Khan, Warren J. Xu, Jong M. Rho, Nellie C. Yee
Publikováno v:
Biochimica et biophysica acta. Molecular basis of disease, vol 1863, iss 9
BackgroundProtein O-linked-β-N-acetyl glucosamine (O-GlcNAc) is a post-translational modification to Ser/Thr residues that integrates energy supply with demand. Abnormal O-GlcNAc patterning is evident in several neurological disease states including
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97b243e0dfbde5eac8e0674bb580d26c
https://escholarship.org/uc/item/1584s4w0
https://escholarship.org/uc/item/1584s4w0
Autor:
Christopher, Newell, Virginia L, Johnsen, Nellie C, Yee, Warren J, Xu, Matthias S, Klein, Aneal, Khan, Jong M, Rho, Jane, Shearer
Publikováno v:
Biochimica et biophysica acta. Molecular basis of disease. 1863(9)
Protein O-linked-β-N-acetyl glucosamine (O-GlcNAc) is a post-translational modification to Ser/Thr residues that integrates energy supply with demand. Abnormal O-GlcNAc patterning is evident in several neurological disease states including epilepsy,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7f28f65e0a3b0170afd6b796c05f0a1f
https://pubmed.ncbi.nlm.nih.gov/28502704
https://pubmed.ncbi.nlm.nih.gov/28502704
Publikováno v:
Life Sciences. 92:657-663
Aims Increased protein O-GlcNAcylation occurs in response to increased availability of glucose and fatty acids and is a hallmark of diabetes. Previous studies have demonstrated an improvement in heart function associated with decreased protein O-GlcN
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c34f2488bc954c0ae1cb4629adea911b
https://doi.org/10.1016/j.lfs.2012.09.007
https://doi.org/10.1016/j.lfs.2012.09.007
Autor:
Lauren G. Koch, Darrell D. Belke, Steven L. Britton, Curtis C. Hughey, Virginia L. Johnsen, Dustin S. Hittel, Jane Shearer, Russell T. Hepple
Publikováno v:
Physiological Genomics. 45:17-25
O-linked β-N-acetyl glucosamine (O-GlcNAc) is a posttranslational modification consisting of a single N-acetylglucosamine moiety attached by an O-β-glycosidic linkage to serine and threonine residues of both nuclear and cytosolic proteins. Analogou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::929e9773d36e6dcadfae8d23c16e9659
https://doi.org/10.1152/physiolgenomics.00111.2012
https://doi.org/10.1152/physiolgenomics.00111.2012
Autor:
Pampee P. Young, Jeffrey N. Rottman, Dustin S. Hittel, Lianli Ma, David H. Wasserman, Virginia L. Johnsen, Jane Shearer, Curtis C. Hughey, Freyja D. James
Publikováno v:
American Journal of Physiology-Endocrinology and Metabolism. 302:E163-E172
Intense interest has been focused on cell-based therapy for the infarcted heart given that stem cells have exhibited the ability to reduce infarct size and mitigate cardiac dysfunction. Despite this, it is unknown whether mesenchymal stem cell (MSC)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e22d2e57183512d6280265e0e3e2d6e8
https://doi.org/10.1152/ajpendo.00443.2011
https://doi.org/10.1152/ajpendo.00443.2011
Autor:
Virginia L. Johnsen, Curtis C. Hughey, Mostafa Ghozlan, Rani Watts, Dustin S. Hittel, Jane Shearer
Although myostatin functions primarily as a negative regulator of skeletal muscle growth and development, accumulating biological and epidemiological evidence indicates an important contributing role in liver disease. In this study, we demonstrate th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d42408c4076a7f0d7b16e60dd83dce6d
https://acuresearchbank.acu.edu.au/item/89qxw/myostatin-inhibits-proliferation-and-insulin-stimulated-glucose-uptake-in-mouse-liver-cells
https://acuresearchbank.acu.edu.au/item/89qxw/myostatin-inhibits-proliferation-and-insulin-stimulated-glucose-uptake-in-mouse-liver-cells
Autor:
Aneal Khan, Dustin S. Hittel, Jane Shearer, Vongai Z. Nyamandi, Curtis C. Hughey, Christopher Newell, Virginia L. Johnsen
Publikováno v:
Obesity (Silver Spring, Md.). 22(3)
Objective The impact of dietary-induced obesity (DIO) on stem cell engraftment and the respective therapeutic potential of stem cell engraftment in DIO have not been reported. The objectives of this study were to examine the impact of DIO on the surv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::048d49895fc496423d01b070308ac94e
https://pubmed.ncbi.nlm.nih.gov/23894091
https://pubmed.ncbi.nlm.nih.gov/23894091
Publikováno v:
The FASEB Journal. 27
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9c24a985e85571c803e3474494bb450b
https://doi.org/10.1096/fasebj.27.1_supplement.1209.21
https://doi.org/10.1096/fasebj.27.1_supplement.1209.21
Myostatin, a member of the transforming growth factor-β (TGF-β) superfamily of secreted proteins, is a potent negative regulator of myogenesis. Free myostatin induces the phosphorylation of the Smad family of transcription factors, which, in turn,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a83e8ebb8c086a90ed882c2bc298113c
https://acuresearchbank.acu.edu.au/item/8v815/myostatin-induced-inhibition-of-the-long-noncoding-rna-malat1-is-associated-with-decreased-myogenesis
https://acuresearchbank.acu.edu.au/item/8v815/myostatin-induced-inhibition-of-the-long-noncoding-rna-malat1-is-associated-with-decreased-myogenesis