Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Virginia K. Vachon"'
Autor:
Shamika Danzy, Virginia K. Vachon, Esther N. Park, Graeme L. Conn, Samantha L. Schwartz, Anice C. Lowen
Publikováno v:
Nucleic Acids Research
2′-5′-Oligoadenylate synthetases (OAS) are innate immune sensors of cytosolic double-stranded RNA (dsRNA) and play a critical role in limiting viral infection. dsRNA binding induces allosteric structural changes in OAS1 that reorganize its cataly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a093557dc2f53f59e701219494fa269
http://europepmc.org/articles/PMC7367156
http://europepmc.org/articles/PMC7367156
Publikováno v:
Nucleic Acids Research
Human 2'-5' oligoadenylate synthetase-1 (OAS1) is central in innate immune system detection of cytoplasmic double-stranded RNA (dsRNA) and promotion of host antiviral responses. However, the molecular signatures that promote OAS1 activation are curre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad4ea7abbd99ef4cbfc56257e9768a72
https://pubmed.ncbi.nlm.nih.gov/25477390
https://pubmed.ncbi.nlm.nih.gov/25477390
Publikováno v:
The Journal of biological chemistry. 289(33)
Virus-associated RNA I (VA RNAI) is a short (∼160-nucleotide) non-coding RNA transcript employed by adenoviruses to subvert the innate immune system protein double-stranded RNA-activated protein kinase (PKR). The central domain of VA RNAI is propos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc0566fe10ebf6f98d8888158a43bd07
https://pubmed.ncbi.nlm.nih.gov/24970889
https://pubmed.ncbi.nlm.nih.gov/24970889
Autor:
Virginia K, Vachon, Graeme L, Conn
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 941
Chemical and enzymatic RNA structure probing methods are important tools for examining RNA secondary and tertiary structures and their interactions with proteins, small molecules, and ions. The recently developed "Selective 2'-Hydroxyl Acylation Anal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4b6fb33122d8f6546da234e107d91f87
https://pubmed.ncbi.nlm.nih.gov/23065560
https://pubmed.ncbi.nlm.nih.gov/23065560
Autor:
Graeme L. Conn, Virginia K. Vachon
Publikováno v:
Recombinant and In Vitro RNA Synthesis ISBN: 9781627031127
Chemical and enzymatic RNA structure probing methods are important tools for examining RNA secondary and tertiary structures and their interactions with proteins, small molecules, and ions. The recently developed "Selective 2'-Hydroxyl Acylation Anal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3f13732bf3d53e0bf3f1f519d8edf3dc
https://doi.org/10.1007/978-1-62703-113-4_12
https://doi.org/10.1007/978-1-62703-113-4_12
Human OAS1 activation is highly dependent on both RNA sequence and context of activating RNA motifs.
Autor:
Schwartz, Samantha L, Park, Esther N, Vachon, Virginia K, Danzy, Shamika, Lowen, Anice C, Conn, Graeme L
Publikováno v:
Nucleic Acids Research; 7/27/2020, Vol. 48 Issue 13, p7520-7531, 12p