Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Virginia H. Black"'
Autor:
Linda C. Quattrochi, Virginia H. Black
Publikováno v:
Drug Metabolism and Disposition. 32:595-602
Aromatic hydrocarbon (AH) effects are mediated by binding of the AH receptor and its heterodimeric partner aromatic hydrocarbon nuclear translocator to specific response elements on DNA (AHREs). CYP1A2 expression is induced by AHs, yet AHREs have bee
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5aa5a6e2b805f27c02e260abb84f7dc
https://doi.org/10.1124/dmd.32.6.595
https://doi.org/10.1124/dmd.32.6.595
Publikováno v:
Archives of Biochemistry and Biophysics. 344:11-17
Guinea pig CYP1A2 cDNA was isolated by RT-PCR from liver tissue of 3,3′-methylcholanthrene-treated guinea pigs. It shares considerable sequence identity with guinea pig CYP1A1 (nt 77%, aa 65%), but differs in levels of constitutive expression, func
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0c59313533fbf339158a523cfeb03cc
https://doi.org/10.1006/abbi.1997.0189
https://doi.org/10.1006/abbi.1997.0189
Publikováno v:
Endocrine Research. 21:315-328
Several immunochemical homologs of hepatic cytochromes P450 (CYPs) capable of steroid catabolism have been identified in the guinea pig adrenal cortex. Their predominance in males suggests a role in sex-differentiated metabolism of androgens. Therefo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe96005ea86d219bf10c193fb1e2471f
https://doi.org/10.3109/07435809509030448
https://doi.org/10.3109/07435809509030448
Autor:
Virginia H. Black
Publikováno v:
The Journal of steroid biochemistry and molecular biology. 43(8)
Several cytochrome P450s have been identified in guinea pig adrenal microsomes which are distinct from the known steroidogenic P450s, c17 and c21, and are immunochemically related to cytochrome P450s found in liver. One, a 52 K protein related to P45
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0835bf06f5e577c6fa58b14b6f43e68
https://pubmed.ncbi.nlm.nih.gov/22217830
https://pubmed.ncbi.nlm.nih.gov/22217830
Autor:
Virginia H. Black, Rachel I. Brody
Publikováno v:
Endocrine Research. 17:195-208
In the guinea pig adrenal the cells of the outer zone secrete high levels of steroid and respond to ACTH with increased synthesis of cholesterol and steroid. The outer zone consists of two cell types: zona fasciculata (ZF) and zona glomerulosa (ZG).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a192ed9f4dbec2c434b1714c48f2edc
https://doi.org/10.1080/07435809109027197
https://doi.org/10.1080/07435809109027197
Publikováno v:
Endocrinology. 146(10)
Steroid-secreting cells are characterized by abundant smooth endoplasmic reticulum whose membranes contain many enzymes involved in sterol and steroid synthesis. Yet they have relatively little morphologically identifiable rough endoplasmic reticulum
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb1ea4a19a684ab6472616c76cd74df2
https://pubmed.ncbi.nlm.nih.gov/15947003
https://pubmed.ncbi.nlm.nih.gov/15947003
Autor:
P.R. Smith, Virginia H. Black
Publikováno v:
Anatomical record. Part B, New anatomist. 278(1)
As have many institutions, the New York University School of Medicine (NYUSM) has instituted curriculum revisions that allow for increased independent study but impose significant time constraints on laboratory courses. Challenged by decreased labora
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be632738bcbaef8177594b3f754f0a47
https://pubmed.ncbi.nlm.nih.gov/15170687
https://pubmed.ncbi.nlm.nih.gov/15170687
Publikováno v:
Endocrine research. 28(4)
Steroid-secreting cells possess abundant smooth endoplasmic reticulum whose membranes contain many enzymes involved in sterol and steroid synthesis. In this study we demonstrate that adrenal smooth microsomal subfractions enriched in these membranes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::584d3c7586784c5cd77cabb1ec2d7fa6
https://pubmed.ncbi.nlm.nih.gov/12530645
https://pubmed.ncbi.nlm.nih.gov/12530645
Publikováno v:
Urology. 44(3)
Heterotopic adrenal tissue has been reported in multiple sites, but its functionality has seldom been assessed. In this case, immunocytochemistry was used to characterize adrenocortical tissue present in the subcapsular region of a nephrectomy specim
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99f93d746a5b081c6c2ee2dbc1ebc647
https://pubmed.ncbi.nlm.nih.gov/8073560
https://pubmed.ncbi.nlm.nih.gov/8073560
Autor:
Virginia H. Black
Publikováno v:
Endocrinology. 135(1)
Guinea pig adrenal microsomes possess a distinctive cytochrome P450 that is immunochemically related to P4501 and correlates with microsomal capacity for xenobiotic metabolism. This 52K protein and the capacity for metabolizing compounds such as ethy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::816c0c3cb16bcc00f4d425757860bb8c
https://pubmed.ncbi.nlm.nih.gov/8013364
https://pubmed.ncbi.nlm.nih.gov/8013364