Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Virginia Díez-Obrero"'
Autor:
Robert Carreras-Torres, Iván Galván-Femenía, Xavier Farré, Beatriz Cortés, Virginia Díez-Obrero, Anna Carreras, Ferran Moratalla-Navarro, Susana Iraola-Guzmán, Natalia Blay, Mireia Obón-Santacana, Víctor Moreno, Rafael de Cid
Publikováno v:
Genome Medicine, Vol 16, Iss 1, Pp 1-22 (2024)
Abstract Background Understanding genetic-metabolite associations has translational implications for informing cardiovascular risk assessment. Interrogating functional genetic variants enhances our understanding of disease pathogenesis and the develo
Externí odkaz:
https://doaj.org/article/4eeb0f9eb5014441b907ed726ca6ad42
Autor:
Zhishan Chen, Xingyi Guo, Ran Tao, Jeroen R. Huyghe, Philip J. Law, Ceres Fernandez-Rozadilla, Jie Ping, Guochong Jia, Jirong Long, Chao Li, Quanhu Shen, Yuhan Xie, Maria N. Timofeeva, Minta Thomas, Stephanie L. Schmit, Virginia Díez-Obrero, Matthew Devall, Ferran Moratalla-Navarro, Juan Fernandez-Tajes, Claire Palles, Kitty Sherwood, Sarah E. W. Briggs, Victoria Svinti, Kevin Donnelly, Susan M. Farrington, James Blackmur, Peter G. Vaughan-Shaw, Xiao-Ou Shu, Yingchang Lu, Peter Broderick, James Studd, Tabitha A. Harrison, David V. Conti, Fredrick R. Schumacher, Marilena Melas, Gad Rennert, Mireia Obón-Santacana, Vicente Martín-Sánchez, Jae Hwan Oh, Jeongseon Kim, Sun Ha Jee, Keum Ji Jung, Sun-Seog Kweon, Min-Ho Shin, Aesun Shin, Yoon-Ok Ahn, Dong-Hyun Kim, Isao Oze, Wanqing Wen, Keitaro Matsuo, Koichi Matsuda, Chizu Tanikawa, Zefang Ren, Yu-Tang Gao, Wei-Hua Jia, John L. Hopper, Mark A. Jenkins, Aung Ko Win, Rish K. Pai, Jane C. Figueiredo, Robert W. Haile, Steven Gallinger, Michael O. Woods, Polly A. Newcomb, David Duggan, Jeremy P. Cheadle, Richard Kaplan, Rachel Kerr, David Kerr, Iva Kirac, Jan Böhm, Jukka-Pekka Mecklin, Pekka Jousilahti, Paul Knekt, Lauri A. Aaltonen, Harri Rissanen, Eero Pukkala, Johan G. Eriksson, Tatiana Cajuso, Ulrika Hänninen, Johanna Kondelin, Kimmo Palin, Tomas Tanskanen, Laura Renkonen-Sinisalo, Satu Männistö, Demetrius Albanes, Stephanie J. Weinstein, Edward Ruiz-Narvaez, Julie R. Palmer, Daniel D. Buchanan, Elizabeth A. Platz, Kala Visvanathan, Cornelia M. Ulrich, Erin Siegel, Stefanie Brezina, Andrea Gsur, Peter T. Campbell, Jenny Chang-Claude, Michael Hoffmeister, Hermann Brenner, Martha L. Slattery, John D. Potter, Kostas K. Tsilidis, Matthias B. Schulze, Marc J. Gunter, Neil Murphy, Antoni Castells, Sergi Castellví-Bel, Leticia Moreira, Volker Arndt, Anna Shcherbina, D. Timothy Bishop, Graham G. Giles, Melissa C. Southey, Gregory E. Idos, Kevin J. McDonnell, Zomoroda Abu-Ful, Joel K. Greenson, Katerina Shulman, Flavio Lejbkowicz, Kenneth Offit, Yu-Ru Su, Robert Steinfelder, Temitope O. Keku, Bethany van Guelpen, Thomas J. Hudson, Heather Hampel, Rachel Pearlman, Sonja I. Berndt, Richard B. Hayes, Marie Elena Martinez, Sushma S. Thomas, Paul D. P. Pharoah, Susanna C. Larsson, Yun Yen, Heinz-Josef Lenz, Emily White, Li Li, Kimberly F. Doheny, Elizabeth Pugh, Tameka Shelford, Andrew T. Chan, Marcia Cruz-Correa, Annika Lindblom, David J. Hunter, Amit D. Joshi, Clemens Schafmayer, Peter C. Scacheri, Anshul Kundaje, Robert E. Schoen, Jochen Hampe, Zsofia K. Stadler, Pavel Vodicka, Ludmila Vodickova, Veronika Vymetalkova, Christopher K. Edlund, W. James Gauderman, David Shibata, Amanda Toland, Sanford Markowitz, Andre Kim, Stephen J. Chanock, Franzel van Duijnhoven, Edith J. M. Feskens, Lori C. Sakoda, Manuela Gago-Dominguez, Alicja Wolk, Barbara Pardini, Liesel M. FitzGerald, Soo Chin Lee, Shuji Ogino, Stephanie A. Bien, Charles Kooperberg, Christopher I. Li, Yi Lin, Ross Prentice, Conghui Qu, Stéphane Bézieau, Taiki Yamaji, Norie Sawada, Motoki Iwasaki, Loic Le Marchand, Anna H. Wu, Chenxu Qu, Caroline E. McNeil, Gerhard Coetzee, Caroline Hayward, Ian J. Deary, Sarah E. Harris, Evropi Theodoratou, Stuart Reid, Marion Walker, Li Yin Ooi, Ken S. Lau, Hongyu Zhao, Li Hsu, Qiuyin Cai, Malcolm G. Dunlop, Stephen B. Gruber, Richard S. Houlston, Victor Moreno, Graham Casey, Ulrike Peters, Ian Tomlinson, Wei Zheng
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Genome-wide association studies (GWAS) have identified more than 200 common genetic variants independently associated with colorectal cancer (CRC) risk, but the causal variants and target genes are mostly unknown. We sought to fine-map all k
Externí odkaz:
https://doaj.org/article/a9c9d74556364a62b1ef09719244a952
Autor:
Mireia Obón-Santacana, Ferran Moratalla-Navarro, Elisabet Guinó, Robert Carreras-Torres, Virginia Díez-Obrero, David Bars-Cortina, Gemma Ibáñez-Sanz, Lorena Rodríguez-Alonso, Alfredo Mata, Ana García-Rodríguez, Matthew Devall, Graham Casey, Li Li, Victor Moreno
Publikováno v:
Nutrients, Vol 16, Iss 18, p 3131 (2024)
(1) Introduction: The global rise of gastrointestinal diseases, including colorectal cancer and inflammatory bowel diseases, highlights the need to understand their causes. Diet is a common risk factor and a crucial regulator of gene expression, with
Externí odkaz:
https://doaj.org/article/a4eafbcb333741a8aaa84109020f0244
Autor:
Aida Ferreiro-Iglesias, James D. McKay, Nicole Brenner, Shama Virani, Corina Lesseur, Valerie Gaborieau, Andy R. Ness, Rayjean J. Hung, Geoffrey Liu, Brenda Diergaarde, Andrew F. Olshan, Neil Hayes, Mark C. Weissler, Lea Schroeder, Noemi Bender, Michael Pawlita, Steve Thomas, Miranda Pring, Tom Dudding, Beatriz Kanterewicz, Robert Ferris, Sera Thomas, Yonathan Brhane, Virginia Díez-Obrero, Maja Milojevic, Karl Smith-Byrne, Daniela Mariosa, Mattias J. Johansson, Rolando Herrero, Stefania Boccia, Gabriella Cadoni, Martin Lacko, Ivana Holcátová, Wolfgang Ahrens, Pagona Lagiou, Areti Lagiou, Jerry Polesel, Lorenzo Simonato, Franco Merletti, Claire M. Healy, Bo T. Hansen, Mari Nygård, David I. Conway, Sylvia Wright, Tatiana V. Macfarlane, Max Robinson, Laia Alemany, Antonio Agudo, Ariana Znaor, Christopher I. Amos, Tim Waterboer, Paul Brennan
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
Genetic susceptibility loci for oropharyngeal cancer have been reported but these studies have not always examined human papillomavirus (HPV) status. Here, the authors perform genome-wide analysis taking into account HPV16 serology status and report
Externí odkaz:
https://doaj.org/article/2fea871dd83e4073bda71eb391ac7fa0
Autor:
Rosario Ferrer‐Avargues, María Isabel Castillejo, Estela Dámaso, Virginia Díez‐Obrero, Noemí Garrigos, Tatiana Molina, Alan Codoñer‐Alejos, Ángel Segura, Ana Beatriz Sánchez‐Heras, Adela Castillejo, José Luis Soto
Publikováno v:
Cancer Communications, Vol 41, Iss 3, Pp 218-228 (2021)
Abstract Background Lynch syndrome (LS) is a hereditary condition characterized by a high risk of colorectal cancer, endometrial cancer, and other neoplasia associated with germline alterations in DNA mismatch repair genes. The classical genetic diag
Externí odkaz:
https://doaj.org/article/1ecd637319c94345af1605f294d9face
Autor:
Virginia Díez-Obrero, Christopher H. Dampier, Ferran Moratalla-Navarro, Matthew Devall, Sarah J. Plummer, Anna Díez-Villanueva, Ulrike Peters, Stephanie Bien, Jeroen R. Huyghe, Anshul Kundaje, Gemma Ibáñez-Sanz, Elisabeth Guinó, Mireia Obón-Santacana, Robert Carreras-Torres, Graham Casey, Víctor Moreno
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 12, Iss 1, Pp 181-197 (2021)
Background & Aims: The association of genetic variation with tissue-specific gene expression and alternative splicing guides functional characterization of complex trait-associated loci and may suggest novel genes implicated in disease. Here, our aim
Externí odkaz:
https://doaj.org/article/30ac87a71639435e9d33d43bfe4707af
Autor:
James Yarmolinsky, Virginia Díez-Obrero, Tom G Richardson, Marie Pigeyre, Jennifer Sjaarda, Guillaume Paré, Venexia M Walker, Emma E Vincent, Vanessa Y Tan, Mireia Obón-Santacana, Demetrius Albanes, Jochen Hampe, Andrea Gsur, Heather Hampel, Rish K Pai, Mark Jenkins, Steven Gallinger, Graham Casey, Wei Zheng, Christopher I Amos, International Lung Cancer Consortium, PRACTICAL consortium, MEGASTROKE consortium, George Davey Smith, Richard M Martin, Victor Moreno
Publikováno v:
PLoS Medicine, Vol 19, Iss 2, p e1003897 (2022)
BackgroundEpidemiological studies have reported conflicting findings on the potential adverse effects of long-term antihypertensive medication use on cancer risk. Naturally occurring variation in genes encoding antihypertensive drug targets can be us
Externí odkaz:
https://doaj.org/article/34b1a0c7008a49a584262cd8aef7a5ec
Autor:
Xavier Vallès, M. Henar Alonso, Juan Francisco López-Caleya, Virginia Díez-Obrero, Trinidad Dierssen-Sotos, Virginia Lope, Ana Molina-Barceló, María Dolores Chirlaque, José Juan Jiménez-Moleón, Guillermo Fernández Tardón, Jesús Castilla, Pilar Amiano, Rocío Capelo, Gemma Castaño-Vinyals, Elisabet Guinó, Antonio José Molina de la Torre, Conchi Moreno-Iribas, Beatriz Pérez Gómez, Nuria Aragonés, Javier Llorca, Vicente Martín, Manolis Kogevinas, Marina Pollán, Victor Moreno
Publikováno v:
Environment International, Vol 121, Iss , Pp 428-434 (2018)
Objectives: To explore the association of colorectal cancer with environmental solar radiation and sun exposure behavior, considering phenotypic variables (eye color, hair color and skin phenotype), dietary intake of vitamin D and calcium, and socio-
Externí odkaz:
https://doaj.org/article/a187e486b5cc47d4aa323d5835fbea27
Autor:
Graham Casey, Ulrike Peters, Andrew T. Chan, Steven M. Powell, Victor Moreno, Ömer H. Yilmaz, Mourad W. Ali, Lucas T. Jennelle, Oliver Takacsi-Nagy, Dylan C. Zerjav, Dmitriy Kedrin, Jiancheng Mo, Virginia Díez-Obrero, Jennifer Bryant, Stephen Eaton, Sarah J. Plummer, Christopher H. Dampier, David A. Drew, Matthew A.M. Devall
Supplementary Figure from Transcriptome-wide In Vitro Effects of Aspirin on Patient-derived Normal Colon Organoids
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f9f444a0cc02bff455a3fbf9d9920e2
https://doi.org/10.1158/1940-6207.22533655.v1
https://doi.org/10.1158/1940-6207.22533655.v1
Autor:
Graham Casey, Ulrike Peters, Andrew T. Chan, Steven M. Powell, Victor Moreno, Ömer H. Yilmaz, Mourad W. Ali, Lucas T. Jennelle, Oliver Takacsi-Nagy, Dylan C. Zerjav, Dmitriy Kedrin, Jiancheng Mo, Virginia Díez-Obrero, Jennifer Bryant, Stephen Eaton, Sarah J. Plummer, Christopher H. Dampier, David A. Drew, Matthew A.M. Devall
Supplementary Data from Transcriptome-wide In Vitro Effects of Aspirin on Patient-derived Normal Colon Organoids
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e64137ab41b980acf7a5ac5cd86333b
https://doi.org/10.1158/1940-6207.22533673.v1
https://doi.org/10.1158/1940-6207.22533673.v1