Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Virginia C. Morris"'
Publikováno v:
Journal of Toxicology and Environmental Health, Part A. 63:511-523
An amyocarditic strain of coxsackievirus B3 (CVB3/0) induces heart damage when inoculated into selenium (Se)-deficient mice. Mercury (Hg), an Se antagonist, is known to aggravate viral infections. The experiments reported here assessed the effect of
Publikováno v:
International Journal for Vitamin and Nutrition Research. 71:87-92
Gluthatione peroxidase and thioredoxin reductase are selenocysteine-containing enzymes that are constituents of the cellular antioxidant defense system. Conventional cuvette-based assays for glutathione peroxidase and thioredoxin reductase enzymes ar
Publikováno v:
The Journal of Nutrition. 129:194-198
Gold (I)-containing compounds, including aurothioglucose (ATG), are potent in vitro inhibitors of several selenocysteine-containing enzymes. Gold compounds have also been shown to potentiate the virulence of several viruses in mice, including coxsack
Publikováno v:
Lipids. 30:1053-1056
Excretion of malondialdehyde (MDA)-generating substances in the urine has been suggested as an indicator of in vivo lipid peroxidation. However, MDA in the urine also reflects the amount of lipid peroxidation products consumed in the diet. We determi
Autor:
Orville A. Levander, Virginia C. Morris, Melinda A. Beck, Qing Shi, Lisa H. Rohr, Peter C. Kolbeck
Publikováno v:
Journal of Infectious Diseases. 170:351-357
Coxsackievirus B3 (CVB3/20)-induced myocarditic lesions occurred more quickly and were more severe and virus titers in heart and liver were higher in selenium (Se)-deficient than Se-adequate mice. NK cell activity and serum neutralizing antibody tite
Autor:
Orville A. Levander, Lisa H. Rohr, Peter C. Kolbeck, Qing Shi, Melinda A. Beck, Virginia C. Morris
Publikováno v:
Journal of Medical Virology. 43:166-170
Coxsackieviruses have been implicated as possible co-factors in the etiology of the selenium (Se)-responsive cardiomyopathy known as Keshan disease. Here we report that a cloned and sequenced amyocarditic coxsackievirus B3 (CVB3/0), which causes no p
Publikováno v:
Nutrition Research. 13:31-36
Because selenium (Se) compounds may have anticarcinogenic properties, noninvasive techniques to monitor Se status are needed. Hair and nails have been suggested, but earlier work by us showed that their Se content is a function of the amount ingested
Publikováno v:
Nutrition Research. 11:941-948
Vitamin E-deficient diets containing 5 to 20% ground flaxseed or 2.75% ethyl linolenate protected mice against the malarial parasite Plasmodium yoelii as shown by decreased parasitemia and enhanced survival. Although the biochemical mechanism of thes
Publikováno v:
Free radical biologymedicine. 38(1)
Several oxidative stressors (dietary selenium deficiency, dietary vitamin E deficiency coupled with fish oil feeding, genetic reduction of glutathione peroxidase activity) allow a normally benign coxsackievirus B3 (CVB3/0) to damage heart muscle in h
Publikováno v:
Nature medicine. 1(5)
Previous work from our laboratory demonstrated that selenium deficiency in the mouse allows a normally benign (amyocarditic) cloned and sequenced Coxackievirus to cause significant heart damage. Furthermore, Coxsackievirus recovered from the hearts o