Zobrazeno 1 - 10
of 592
pro vyhledávání: '"Virginia B Kraus"'
Autor:
Hikmat N Daghestani, Joanne M Jordan, Jordan B Renner, Michael Doherty, A Gerry Wilson, Virginia B Kraus
Publikováno v:
PLoS ONE, Vol 12, Iss 12, p e0190251 (2017)
OBJECTIVE:Cartilage homeostasis relies on a balance of catabolism and anabolism of cartilage matrix. Our goal was to evaluate the burden of radiographic osteoarthritis and serum levels of type IIA procollagen amino terminal propeptide (sPIIANP), a bi
Externí odkaz:
https://doaj.org/article/6526c90c7ce94286a7e79bad6c2c3756
Autor:
Martha C Castaño-Betancourt, Dan S Evans, Yolande F M Ramos, Cindy G Boer, Sarah Metrustry, Youfang Liu, Wouter den Hollander, Jeroen van Rooij, Virginia B Kraus, Michelle S Yau, Braxton D Mitchell, Kenneth Muir, Albert Hofman, Michael Doherty, Sally Doherty, Weiya Zhang, Robert Kraaij, Fernando Rivadeneira, Elizabeth Barrett-Connor, Rose A Maciewicz, Nigel Arden, Rob G H H Nelissen, Margreet Kloppenburg, Joanne M Jordan, Michael C Nevitt, Eline P Slagboom, Deborah J Hart, Floris Lafeber, Unnur Styrkarsdottir, Eleftheria Zeggini, Evangelos Evangelou, Tim D Spector, Andre G Uitterlinden, Nancy E Lane, Ingrid Meulenbelt, Ana M Valdes, Joyce B J van Meurs
Publikováno v:
PLoS Genetics, Vol 12, Iss 10, p e1006260 (2016)
Osteoarthritis is one of the most frequent and disabling diseases of the elderly. Only few genetic variants have been identified for osteoarthritis, which is partly due to large phenotype heterogeneity. To reduce heterogeneity, we here examined carti
Externí odkaz:
https://doaj.org/article/346cded1a0c64f81b7b42090748bb1f4
Autor:
Shirley P. Yu, Leticia A. Deveza, Virginia B. Kraus, Morten Karsdal, Anne-Christine Bay-Jensen, Jamie E. Collins, Ali Guermazi, Frank W. Roemer, Christoph Ladel, Venkatesha Bhagavath, David J. Hunter
Publikováno v:
Arthritis Research & Therapy, Vol 26, Iss 1, Pp 1-13 (2024)
Abstract Background To assess the prognostic value of short-term change in biochemical markers as it relates to bone marrow lesions (BMLs) on MRI in knee osteoarthritis (OA) over 24 months and, furthermore, to assess the relationship between biochemi
Externí odkaz:
https://doaj.org/article/66a88f0b88a841a7a733440fa117c61f
Autor:
Daniel Nolan, William E Kraus, Elizabeth Hauser, Yi-Ju Li, Dana K Thompson, Jessica Johnson, Hsiang-Cheng Chen, Sarah Nelson, Carol Haynes, Simon G Gregory, Virginia B Kraus, Svati H Shah
Publikováno v:
PLoS ONE, Vol 8, Iss 8, p e71779 (2013)
Given the importance of cardiovascular disease (CVD) to public health and the demonstrated heritability of both disease status and its related risk factors, identifying the genetic variation underlying these susceptibilities is a critical step in und
Externí odkaz:
https://doaj.org/article/9a7637d26c0546b8ae2e88af9194932a
Autor:
Kim M Huffman, Leanne M Redman, Lawrence R Landerman, Carl F Pieper, Robert D Stevens, Michael J Muehlbauer, Brett R Wenner, James R Bain, Virginia B Kraus, Christopher B Newgard, Eric Ravussin, William E Kraus
Publikováno v:
PLoS ONE, Vol 7, Iss 4, p e28190 (2012)
To determine if caloric restriction (CR) would cause changes in plasma metabolic intermediates in response to a mixed meal, suggestive of changes in the capacity to adapt fuel oxidation to fuel availability or metabolic flexibility, and to determine
Externí odkaz:
https://doaj.org/article/02e6b7fb4190457b8721f0b5c8321b7b
Publikováno v:
PLoS ONE, Vol 5, Iss 3, p e9739 (2010)
Osteoarthritis (OA) is a debilitating chronic multijoint disease of global proportions. OA presence and severity is usually documented by x-ray imaging but whole body imaging is impractical due to radiation exposure, time and cost. Systemic (serum or
Externí odkaz:
https://doaj.org/article/d7f2b114d10349849837eecd5adf0500
Autor:
Akshay Bareja, David E. Lee, Tricia Ho, Greg Waitt, Lauren H. McKay, Sarah A. Hannou, Melissa C. Orenduff, Kristen M. McGreevy, Alexandra Binder, Calen P. Ryan, Erik J. Soderblom, Daniel W. Belsky, Luigi Ferrucci, Jayanta Kumar Das, Nirad Banskota, Virginia B. Kraus, Janet L. Huebner, William E. Kraus, Kim M. Huffman, Gurpreet S. Baht, Steve Horvath, Robert J. Parmer, Lindsey A. Miles, James P. White
Publikováno v:
Cell Reports, Vol 43, Iss 3, Pp 113881- (2024)
Summary: An intriguing effect of short-term caloric restriction (CR) is the expansion of certain stem cell populations, including muscle stem cells (satellite cells), which facilitate an accelerated regenerative program after injury. Here, we utilize
Externí odkaz:
https://doaj.org/article/427aacba1e9c45278727a51ef1f744a6
Autor:
Yao Fu, Albert Batushansky, Michael Kinter, Janet L. Huebner, Virginia B. Kraus, Timothy M. Griffin
Publikováno v:
JBMR Plus, Vol 7, Iss 7, Pp n/a-n/a (2023)
ABSTRACT Leptin is a proinflammatory adipokine that contributes to obesity‐associated osteoarthritis (OA), especially in women. However, the extent to which leptin causes knee OA separate from the effect of increased body weight is not clear. We hy
Externí odkaz:
https://doaj.org/article/aa1cc937840a407a886dca46ed902848
Autor:
Adam P. Goode, David Hu, Steven Z. George, Todd A. Schwartz, Virginia B. Kraus, Janet L. Huebner, Rebecca J. Cleveland, Kenneth A. Taylor, Joanne M. Jordan, Yvonne M. Golightly
Publikováno v:
Osteoarthritis and Cartilage Open, Vol 4, Iss 3, Pp 100270- (2022)
Objective: Describe the association between biomarkers and lumbar spine degeneration (vertebral osteophytes [OST], facet joint osteoarthritis [FOA], and disc space narrowing [DSN]), for persons with and without low back pain (LBP) and determine wheth
Externí odkaz:
https://doaj.org/article/dbf4880876a1468590395f85fb58089b
Autor:
Christopher G Vann, Xin Zhang, Alastair Khodabukus, Melissa C. Orenduff, Yu-Hsiu Chen, David L. Corcoran, George A. Truskey, Nenad Bursac, Virginia B. Kraus
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
Exercise affects the expression of microRNAs (miR/s) and muscle-derived extracellular vesicles (EVs). To evaluate sarcoplasmic and secreted miR expression in human skeletal muscle in response to exercise-mimetic contractile activity, we utilized a th
Externí odkaz:
https://doaj.org/article/01b3dc9dd88a468698e95c74c8051b9e