Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Virginia Alvarez-Garcia"'
Autor:
Virginia Alvarez-Garcia, Clare Bartos, Ieva Keraite, Urmi Trivedi, Paul M. Brennan, Maïwenn Kersaudy-Kerhoas, Karim Gharbi, Olga Oikonomidou, Nicholas R. Leslie
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-1 (2021)
Externí odkaz:
https://doaj.org/article/ebeb4d8f08af438b829314aced4ffe4d
Autor:
Dolores Hambardzumyan, David H. Gutmann, Susanne A. Wolf, Sandra Seby, Bhakti Dwivedi, Rikke Rasmussen, Winnie W. Pong, Kai Nie, Virginia Alvarez Garcia, Cameron J. Herting, Xi Feng, Zhihong Chen
Dynamic modulation of CCR2 and CX3CR1 in myeloid cells isolated from tumors. With the decrease of Ly6C intensity, the cells present increased CX3CR1-GFP intensity but decreased CCR2-RFP intensity.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6179e8bd48542bc662f81b9cd0ce862e
https://doi.org/10.1158/0008-5472.22415670.v1
https://doi.org/10.1158/0008-5472.22415670.v1
Autor:
Dolores Hambardzumyan, David H. Gutmann, Susanne A. Wolf, Sandra Seby, Bhakti Dwivedi, Rikke Rasmussen, Winnie W. Pong, Kai Nie, Virginia Alvarez Garcia, Cameron J. Herting, Xi Feng, Zhihong Chen
Figure S1. Circulating Ly6CHi inflammatory monocytes diminish at terminal illness. Figure S2. Enhanced BM-derived cell infiltration in Cx3cr1GFP/GFP;Ccr2RFP/WT mice. Figure S3. RFP+ cells are only observed in the meninges in healthy naïve Cx3cr1GFP/
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::023b70cbbc9bda0a382cb9303e1d647a
https://doi.org/10.1158/0008-5472.22415673.v1
https://doi.org/10.1158/0008-5472.22415673.v1
Autor:
Dolores Hambardzumyan, David H. Gutmann, Susanne A. Wolf, Sandra Seby, Bhakti Dwivedi, Rikke Rasmussen, Winnie W. Pong, Kai Nie, Virginia Alvarez Garcia, Cameron J. Herting, Xi Feng, Zhihong Chen
In glioblastoma (GBM), tumor-associated macrophages (TAM) represent up to one half of the cells of the tumor mass, including both infiltrating macrophages and resident brain microglia. In an effort to delineate the temporal and spatial dynamics of TA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ea452c19293e40a1c40bf9ef906a20a
https://doi.org/10.1158/0008-5472.c.6509349.v1
https://doi.org/10.1158/0008-5472.c.6509349.v1
Publikováno v:
Methods in Molecular Biology ISBN: 9781071629499
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a611af1415b3bcedb7cae8a71433e5ce
https://doi.org/10.1007/978-1-0716-2950-5_4
https://doi.org/10.1007/978-1-0716-2950-5_4
Autor:
Maïwenn Kersaudy-Kerhoas, Olga Oikonomidou, Nick R. Leslie, Ieva Keraite, Nicholas C. Turner, Isaac Garcia-Murillas, Clare Bartos, Virginia Alvarez-Garcia, Matthew Beaney
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
Scientific Reports
Sci Rep . 2020 Oct 13;10(1):17082
UCrea Repositorio Abierto de la Universidad de Cantabria
Universidad de Cantabria (UC)
Keraite, I, Alvarez Garcia, V, Garcia-Murillas, I, Beaney, M, C Turner, N, Bartos, C, Oikonomidou, O, Kersaudy-Kerhoas, M & R. Leslie, N 2020, ' PIK3CA mutation enrichment and quantitation from blood and tissue ', Scientific Reports . https://doi.org/10.1038/s41598-020-74086-w
Scientific Reports
Sci Rep . 2020 Oct 13;10(1):17082
UCrea Repositorio Abierto de la Universidad de Cantabria
Universidad de Cantabria (UC)
Keraite, I, Alvarez Garcia, V, Garcia-Murillas, I, Beaney, M, C Turner, N, Bartos, C, Oikonomidou, O, Kersaudy-Kerhoas, M & R. Leslie, N 2020, ' PIK3CA mutation enrichment and quantitation from blood and tissue ', Scientific Reports . https://doi.org/10.1038/s41598-020-74086-w
PIK3CA is one of the two most frequently mutated genes in breast cancers, occurring in 30–40% of cases. Four frequent ‘hotspot’ PIK3CA mutations (E542K, E545K, H1047R and H1047L) account for 80–90% of all PIK3CA mutations in human malignancie
Publikováno v:
Seminars in Cancer Biology. 59:66-79
PTEN is a phosphatase which metabolises PIP3, the lipid product of PI 3-Kinase, directly opposing the activation of the oncogenic PI3K/AKT/mTOR signalling network. Accordingly, loss of function of the PTEN tumour suppressor is one of the most common
Autor:
Urmi Trivedi, Clare Bartos, Virginia Alvarez-Garcia, Paul Brennan, Maïwenn Kersaudy-Kerhoas, Olga Oikonomidou, Ieva Keraite, Karim Gharbi, Nick R. Leslie
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-1 (2021)
Publikováno v:
Biochemical Society Transactions. 44:273-278
The phosphatase and tensin homologue deleted on chromosome 10 (PTEN) phosphatase dephosphorylates PIP3, the lipid product of the class I PI 3-kinases, and suppresses the growth and proliferation of many cell types. It has been heavily studied, in lar
Autor:
Ieva Keraite, Maïwenn Kersaudy-Kerhoas, Nick R. Leslie, Virginia Alvarez-Garcia, Jurgen Del Favero
Publikováno v:
Clinical Cancer Research. 26:B55-B55
The PI3K/AKT/mTOR signaling pathway is one of the most frequently mutated pathways in human cancers, including breast cancer. Given the current urge for more personalized approaches, there is an increasing need for a rigorous list of biomarkers and d