Výsledky vyhledávání - "Virgile Tellier"

Akademický článek

CTCF modulates allele-specific sub-TAD organization and imprinted gene activity at the mouse Dlk1-Dio3 and Igf2-H19 domains

Autor: David Llères, Benoît Moindrot, Rakesh Pathak, Vincent Piras, Mélody Matelot, Benoît Pignard, Alice Marchand, Mallory Poncelet, Aurélien Perrin, Virgile Tellier, Robert Feil, Daan Noordermeer

Publikováno v: Genome Biology, Vol 20, Iss 1, Pp 1-17 (2019)

Abstract Background Genomic imprinting is essential for mammalian development and provides a unique paradigm to explore intra-cellular differences in chromatin configuration. So far, the detailed allele-specific chromatin organization of imprinted ge

Externí odkaz: https://doaj.org/article/6246306ae90347bbb877362b3c3099bb

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CTCF modulates allele-specific sub-TAD organization and imprinted gene activity at the mouse Dlk1-Dio3 and Igf2-H19 domains

Autor: Mallory Poncelet, Mélody Matelot, Daan Noordermeer, Benoît Moindrot, Vincent Piras, Virgile Tellier, Robert Feil, Benoît Pignard, Aurélien Perrin, Rakesh Pathak, David Llères, Alice Marchand

Publikováno v: Genome Biology
Genome Biology, 2019, 20 (1), pp.272. ⟨10.1186/s13059-019-1896-8⟩
Genome Biology, Vol 20, Iss 1, Pp 1-17 (2019)
Genome Biology, BioMed Central, 2019, 20 (1), pp.272. ⟨10.1186/s13059-019-1896-8⟩

BackgroundGenomic imprinting is essential for mammalian development and provides a unique paradigm to explore intra-cellular differences in chromatin configuration. So far, the detailed allele-specific chromatin organization of imprinted gene domains

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e62d137fc623e1b111799393c3c2b566
https://doi.org/10.1186/s13059-019-1896-8

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CTCF controls imprinted gene activity at the mouseDlk1-Dio3andIgf2-H19domains by modulating allele-specific sub-TAD structure

Autor: Daan Noordermeer, Vincent Piras, Rakesh Pathak, Robert Feil, Alice Marchand, Virgile Tellier, Benoît Pignard, David Llères, Mélody Matelot, Benoît Moindrot, Mallory Poncelet, Aurélien Perrin

SUMMARYMammalian genomic imprinting is essential for development and provides a unique paradigm to explore intra-cellular differences in chromatin configuration. Here, we compared chromatin structure of the two conserved imprinted domains controlled

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f8a1bd138b2409f6f243944b9332b66
https://doi.org/10.1101/633065

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Abstract 668: A recommender system to enhance drug development in oncology from phase I trials: The RESOLVED2 project

Autor: Guillaume Beinse, Virgile Tellier, Valentin Charvet, Isabelle Borget, Christophe Massard, Antoine Hollebecque, Loic Verlingue

Publikováno v: Cancer Research. 79:668-668

The industry and investigators’ communities are currently facing a conjunction of increasing number of anti-neoplastic agents (ANA) candidate for phase 1 clinical trials (P1CT) and an important attrition rate for final approval. Improvement of the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::644de5c4a646a64dcd208d24283020f2
https://doi.org/10.1158/1538-7445.am2019-668

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