Zobrazeno 1 - 10
of 95
pro vyhledávání: '"Virendra Gajbhiye"'
Autor:
Sherin Varghese, M.S. Jisha, K.C. Rajeshkumar, Virendra Gajbhiye, Abdulwahed Fahad Alrefaei, Rajesh Jeewon
Publikováno v:
Heliyon, Vol 10, Iss 13, Pp e33995- (2024)
Globally, breast cancer is a primary contributor to cancer-related fatalities and illnesses among women. Consequently, there is a pressing need for safe and effective treatments for breast cancer. Bioactive compounds from endophytic fungi that live i
Externí odkaz:
https://doaj.org/article/37a97e3026c147f7927aa1bd850f002c
Publikováno v:
Frontiers in Virology, Vol 4 (2024)
Chikungunya virus (CHIKV) is a vector-born alphavirus responsible for chikungunya fever with clinical manifestation of polyarthritis transmitted by Aedes aegypti and Aedes albopictus. Establishing viral pathogenesis needs host machinery modulation, a
Externí odkaz:
https://doaj.org/article/91a2bcf164dd4b3dbd195576deade335
Autor:
Rajesh Salve, Niladri Haldar, Aazam Shaikh, Rajkumar Samanta, Devyani Sengar, Surajit Patra, Virendra Gajbhiye
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 12 (2024)
With a prevalence of 12.5% of all new cancer cases annually, breast cancer stands as the most common form of cancer worldwide. The current therapies utilized for breast cancer are constrained and ineffective in addressing the condition. siRNA-based g
Externí odkaz:
https://doaj.org/article/a1f1f5e433d848d6a5233ab8d899344e
Autor:
Kavita R. Gajbhiye, Rajesh Salve, Mahavir Narwade, Afsana Sheikh, Prashant Kesharwani, Virendra Gajbhiye
Publikováno v:
Molecular Cancer, Vol 22, Iss 1, Pp 1-44 (2023)
Abstract Lipid-based polymeric nanoparticles are the highly popular carrier systems for cancer drug therapy. But presently, detailed investigations have revealed their flaws as drug delivery carriers. Lipid polymer hybrid nanoparticles (LPHNPs) are a
Externí odkaz:
https://doaj.org/article/d57af45ce20f463d9f123a35d25d8b74
Advanced cancer targeting using aptamer functionalized nanocarriers for site-specific cargo delivery
Publikováno v:
Biomaterials Research, Vol 27, Iss 1, Pp 1-36 (2023)
Abstract The non-specificity of standard anticancer therapies has profound detrimental consequences in clinical treatment. Therapeutic specificity can be precisely achieved using cutting-edge ligands. Small synthetic oligonucleotide-ligands chosen th
Externí odkaz:
https://doaj.org/article/7ef9b2c3b28d4547a5a458b1e0f9c6fd
Publikováno v:
Cancer Nanotechnology, Vol 14, Iss 1, Pp 1-11 (2023)
Abstract Cancer is a major threat to human health; thus, early detection is imperative for successful management. Rapid diagnosis can be achieved by imaging primary (subcutaneous) tumors using fluorophores conjugated with tumor markers. Here, the app
Externí odkaz:
https://doaj.org/article/2f44d4d4c4f94be5a5ce9584dfb5805a
Publikováno v:
Journal of Nanobiotechnology, Vol 21, Iss 1, Pp 1-24 (2023)
Abstract Background The adoption of Antiretroviral Therapy (ART) substantially extends the life expectancy and quality of HIV-infected patients. Yet, eliminating the latent reservoirs of HIV to achieve a cure remains an unmet need. The advent of nano
Externí odkaz:
https://doaj.org/article/5b8ec1f8c57848309cc06b70ab07004a
Autor:
Prashant Kesharwani, Mahak Fatima, Vanshikha Singh, Afsana Sheikh, Waleed H. Almalki, Virendra Gajbhiye, Amirhossein Sahebkar
Publikováno v:
Biomimetics, Vol 7, Iss 4, p 206 (2022)
Onychomycosis is a nail infection caused by a fungus, Trichophyton mentagrophytes, that is responsible for major nail infections. The best method suited for treating such infections generally includes a topical remedy. However, conventional oral or t
Externí odkaz:
https://doaj.org/article/67ca213bd38e4bb0a25d4cf63fc7639c
Publikováno v:
Journal of Pharmaceutical Sciences. 112:1450-1459
Publikováno v:
Journal of Controlled Release. 346:328-354
Dendrimers have been comprehensively used for cargo delivery, nucleic acid delivery (genes, miRNA/siRNAs), delivery of macromolecules, and other various biomedical applications. Dendrimers are highly versatile in function and can be engineered as mul