Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Virender S. Aulakh"'
Autor:
Brigitte Rigat, Matthew R. Smith, Hee-Jong Hwang, Virender S. Aulakh, Don J. Mahuran, Sayuri Yonekawa, Jianmin Zhang, Marco A. Ciufolini, Michael B. Tropak
Publikováno v:
Journal of Medicinal Chemistry. 58:4483-4493
In order to identify structural features of pyrimethamine (5-(4-chlorophenyl)-6-ethylpyrimidine-2,4-diamine) that contribute to its inhibitory activity (IC50 value) and chaperoning efficacy toward β-N-acetylhexosaminidase, derivatives of the compoun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d7e3126c7608f824e21f6110970c582
https://doi.org/10.1021/jm5017895
https://doi.org/10.1021/jm5017895
Autor:
Virender S. Aulakh, Marco A. Ciufolini
Publikováno v:
Journal of the American Chemical Society
The total synthesis of the thiopeptide antibiotic, thiocillin I, is described. This work unequivocally defines the full structure (constitution and configuration) of the natural product as 1.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e468952e1699b23f7c258bd52896631b
https://doi.org/10.1021/ja110166x
https://doi.org/10.1021/ja110166x
Autor:
Virender S. Aulakh, Marco A. Ciufolini
Publikováno v:
ChemInform. 41
The oxidation of 2-methylthiazoles to 2-formylthiazoles simplifies the implementation of the Bagley variant of the Bohlmann−Rahtz reaction as a key step in a concise new route to pyridine cores of thiopeptide antibiotics.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1c88eeee0688ef820b79f01fd06efa1e
https://doi.org/10.1002/chin.201001152
https://doi.org/10.1002/chin.201001152
Autor:
Virender S. Aulakh, Shelley Lee, Florian Teyssier, Marco A. Ciufolini, Brian A. Mendelson, Simon Kim
Publikováno v:
ChemInform. 40
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::753749cfe4851be9ab4c4ffa33672dde
https://doi.org/10.1002/chin.200933136
https://doi.org/10.1002/chin.200933136
Autor:
Virender S. Aulakh, Marco A. Ciufolini
Publikováno v:
The Journal of organic chemistry. 74(15)
The oxidation of 2-methylthiazoles to 2-formylthiazoles simplifies the implementation of the Bagley variant of the Bohlmann−Rahtz reaction as a key step in a concise new route to pyridine cores of thiopeptide antibiotics.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c76ebb9af0040fe313d8042023864f98
https://pubmed.ncbi.nlm.nih.gov/19572592
https://pubmed.ncbi.nlm.nih.gov/19572592
Autor:
Shelley Lee, Brian A. Mendelsohn, Marco A. Ciufolini, Florian Teyssier, Virender S. Aulakh, Simon Kim
Publikováno v:
Organic letters. 11(7)
Iodobenzene diacetate in MeOH containing a catalytic amount of TFA efficiently oxidizes aldoximes to nitrile oxides. The latter may be trapped in situ with olefins in a bimolecular or an intramolecular mode. The new method enables the execution of ta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec0a7479b97304b56904fa584cb03059
https://pubmed.ncbi.nlm.nih.gov/19254039
https://pubmed.ncbi.nlm.nih.gov/19254039
Autor:
Sayuri Yonekawa, Marco A. Ciufolini, Kam Ho, Don J. Mahuran, Virender S. Aulakh, Jianmin Zhang, Michael B. Tropak
Publikováno v:
Molecular Genetics and Metabolism. 99:S36
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2d513d19ce909a1db8cb2c88972bb84e
https://doi.org/10.1016/j.ymgme.2009.10.152
https://doi.org/10.1016/j.ymgme.2009.10.152
Autor:
MichaelB. Tropak, Jianmin Zhang, Sayuri Yonekawa, Brigitte A. Rigat, Virender S. Aulakh, Matthew R. Smith, Hee-Jong Hwang, Marco A. Ciufolini, Don J. Mahuran
Publikováno v:
Journal of Medicinal Chemistry; Jun2015, Vol. 58 Issue 11, p4483-4493, 11p
Autor:
Brian A. Mendelsohn, Shelley Lee, Simon Kim, Florian Teyssier, Virender S. Aulakh, Marco A. Ciufolini
Publikováno v:
Organic Letters; Apr2009, Vol. 11 Issue 7, p1539-1542, 4p