Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Viravuth P, Yin"'
Publikováno v:
iScience, Vol 15, Iss , Pp 1-15 (2019)
Summary: The adult zebrafish is capable of regenerating heart muscle, resolving collagen tissue, and fully restoring heart function throughout its life. In this study, we show that the highly upregulated, epicardium-enriched microRNA let-7i functions
Externí odkaz:
https://doaj.org/article/d6c7a6e7758c4d7a9ac6225025243f54
Autor:
Ashley M. Smith, Katie K. Maguire-Nguyen, Thomas A. Rando, Michael A. Zasloff, Kevin B. Strange, Viravuth P. Yin
Publikováno v:
npj Regenerative Medicine, Vol 2, Iss 1, Pp 1-10 (2017)
The enzyme inhibitor that regenerates multiple tissues A naturally occurring small molecule shows promise as a drug for tissue and organ repair and regeneration. Viravuth Yin of the Kathryn W. Davis Center for Regenerative Biology and Medicine with c
Externí odkaz:
https://doaj.org/article/c8757dcf84fd49cead9c2f8b39e2e99b
Autor:
Adriana M. Rodriguez, Viravuth P. Yin
Publikováno v:
Journal of Cardiovascular Development and Disease, Vol 6, Iss 1, p 5 (2019)
Stimulating cardiomyocyte regeneration after an acute injury remains the central goal in cardiovascular regenerative biology. While adult mammals respond to cardiac damage with deposition of rigid scar tissue, adult zebrafish and salamander unleash a
Externí odkaz:
https://doaj.org/article/af81b6273ccc42ee848e5619f29c67bf
Autor:
Benjamin L King, Viravuth P Yin
Publikováno v:
PLoS ONE, Vol 11, Iss 6, p e0157106 (2016)
Although regenerative capacity is evident throughout the animal kingdom, it is not equally distributed throughout evolution. For instance, complex limb/appendage regeneration is muted in mammals but enhanced in amphibians and teleosts. The defining c
Externí odkaz:
https://doaj.org/article/f9c3b576acc04b39a657012af6947f6a
Autor:
Chen-Hui Chen, Alexander F Merriman, Jeremiah Savage, Jason Willer, Taylor Wahlig, Nicholas Katsanis, Viravuth P Yin, Kenneth D Poss
Publikováno v:
PLoS Genetics, Vol 11, Iss 8, p e1005437 (2015)
The first critical stage in salamander or teleost appendage regeneration is creation of a specialized epidermis that instructs growth from underlying stump tissue. Here, we performed a forward genetic screen for mutations that impair this process in
Externí odkaz:
https://doaj.org/article/a35bc80e4f494b3288575a2ac57c97f0
Publikováno v:
iScience. 25:104362
Autor:
Viravuth P. Yin, Daniel J. Kelpsch, Megan Beauchemin, Erika G. Stroh, Tina L. Tootle, Ashley M. Smith, MaryLynn FitzSimons, Maureen C. Lamb
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-10 (2020)
The inability to effectively stimulate cardiomyocyte proliferation remains a principle barrier to regeneration in the adult human heart. A tightly regulated, acute inflammatory response mediated by a range of cell types is required to initiate regene
Autor:
Viravuth P. Yin, Christina A. Dykeman, Benjamin L. King, Michael C. Rosenstein, Ashley M. Smith, Grace A. Smith
Publikováno v:
npj Regenerative Medicine, Vol 3, Iss 1, Pp 1-13 (2018)
NPJ Regenerative Medicine
NPJ Regenerative Medicine
Regeneration is an endogenous process of tissue repair that culminates in complete restoration of tissue and organ function. While regenerative capacity in mammals is limited to select tissues, lower vertebrates like zebrafish and salamanders are end
Autor:
Viravuth P. Yin, Kevin Strange, Michael Zasloff, Thomas A. Rando, Ashley M. Smith, Katie Maguire-Nguyen
Publikováno v:
npj Regenerative Medicine, Vol 2, Iss 1, Pp 1-10 (2017)
NPJ Regenerative Medicine
NPJ Regenerative Medicine
Regenerative medicine holds substantial promise for repairing or replacing tissues and organs damaged by disease, injury, and degeneration. Much of the field has focused on development of cell-based therapeutics, gene-based therapeutics, and tissue e
Autor:
MaryLynn, FitzSimons, Megan, Beauchemin, Ashley M, Smith, Erika G, Stroh, Daniel J, Kelpsch, Maureen C, Lamb, Tina L, Tootle, Viravuth P, Yin
Publikováno v:
Scientific Reports
The inability to effectively stimulate cardiomyocyte proliferation remains a principle barrier to regeneration in the adult human heart. A tightly regulated, acute inflammatory response mediated by a range of cell types is required to initiate regene