Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Virangika K Wimalasena"'
Autor:
S Jimmy Budiardjo, Jacqueline J Stevens, Anna L Calkins, Ayotunde P Ikujuni, Virangika K Wimalasena, Emre Firlar, David A Case, Julie S Biteen, Jason T Kaelber, Joanna SG Slusky
Publikováno v:
eLife, Vol 11 (2022)
The double membrane architecture of Gram-negative bacteria forms a barrier that is impermeable to most extracellular threats. Bacteriocin proteins evolved to exploit the accessible, surface-exposed proteins embedded in the outer membrane to deliver c
Externí odkaz:
https://doaj.org/article/9510bb93037e456488cca7fe070b1f34
Autor:
Jun Qi, Teru Hideshima, Kenneth C. Anderson, Adam D. Durbin, Udo Oppermann, Javed Khan, Shannon Lauberth, Takashi Minami, Mitsuyoshi Nakao, Sumio Ohtsuki, Masao Matsuoka, Nikhil C. Munshi, Yu-Tzu Tai, Mehmet K. Samur, Yawara Kawano, Shingo Usuki, Shinjiro Hino, Yong Kim, Virangika K. Wimalasena, Catrine Johansson, Takeshi Masuda, Chengkui Pei, Deyao Li, Xiaofeng Zhang, Keiji Kurata, Daisuke Ogiya, Berkley E. Gryder, Tingjian Wang, Paul M.C. Park, Hiroto Ohguchi
Supplementary Table 1 listed the genes upregulated and downregulated after treatment with JQKD82 in MM1S cells for 48 h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e84aa2be7384efbe6686f30a58ba273
https://doi.org/10.1158/2643-3230.22543984
https://doi.org/10.1158/2643-3230.22543984
Autor:
Jun Qi, Teru Hideshima, Kenneth C. Anderson, Adam D. Durbin, Udo Oppermann, Javed Khan, Shannon Lauberth, Takashi Minami, Mitsuyoshi Nakao, Sumio Ohtsuki, Masao Matsuoka, Nikhil C. Munshi, Yu-Tzu Tai, Mehmet K. Samur, Yawara Kawano, Shingo Usuki, Shinjiro Hino, Yong Kim, Virangika K. Wimalasena, Catrine Johansson, Takeshi Masuda, Chengkui Pei, Deyao Li, Xiaofeng Zhang, Keiji Kurata, Daisuke Ogiya, Berkley E. Gryder, Tingjian Wang, Paul M.C. Park, Hiroto Ohguchi
Supplementary Figure S1 shows that higher KDM5A expression is associated with poor prognosis in MM.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e704237c08b6a6e879e0516bbaaefff6
https://doi.org/10.1158/2643-3230.22544005.v1
https://doi.org/10.1158/2643-3230.22544005.v1
Autor:
Jun Qi, Teru Hideshima, Kenneth C. Anderson, Adam D. Durbin, Udo Oppermann, Javed Khan, Shannon Lauberth, Takashi Minami, Mitsuyoshi Nakao, Sumio Ohtsuki, Masao Matsuoka, Nikhil C. Munshi, Yu-Tzu Tai, Mehmet K. Samur, Yawara Kawano, Shingo Usuki, Shinjiro Hino, Yong Kim, Virangika K. Wimalasena, Catrine Johansson, Takeshi Masuda, Chengkui Pei, Deyao Li, Xiaofeng Zhang, Keiji Kurata, Daisuke Ogiya, Berkley E. Gryder, Tingjian Wang, Paul M.C. Park, Hiroto Ohguchi
Lysine demethylase 5A (KDM5A) is a negative regulator of histone H3 lysine 4 trimethylation (H3K4me3), a histone mark associated with activate gene transcription. We identify that KDM5A interacts with the P-TEFb complex and cooperates with MYC to c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07e2d62b9170ea08c3ca5fb596a64ef6
https://doi.org/10.1158/2643-3230.c.6550489.v1
https://doi.org/10.1158/2643-3230.c.6550489.v1
Autor:
Jun Qi, A. Thomas Look, Kimberly Stegmaier, Brian J. Abraham, Martha L. Bulyk, Ernst Schönbrunn, John Easton, Olaf Wiest, Taylor R. Quinn, Melissa J. Bikowitz, Antonio R. Perez-Atayde, Amanda L. Robichaud, Amy Saur Conway, Ken Morita, Logan H. Sigua, Paul M.C. Park, Lily Maxham, Maya Mundada, Ying Shao, Anand G. Patel, Stephanie Nance, Noha A.M. Shendy, Luca Mariani, Neekesh V. Dharia, Deyao Li, Mark W. Zimmerman, Virangika K. Wimalasena, Tingjian Wang, Adam D. Durbin
Supplementary Data from EP300 Selectively Controls the Enhancer Landscape of MYCN-Amplified Neuroblastoma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::700913e64764f6e6c15c2df8eb0c5d30
https://doi.org/10.1158/2159-8290.22541228
https://doi.org/10.1158/2159-8290.22541228
Autor:
Jun Qi, Teru Hideshima, Kenneth C. Anderson, Adam D. Durbin, Udo Oppermann, Javed Khan, Shannon Lauberth, Takashi Minami, Mitsuyoshi Nakao, Sumio Ohtsuki, Masao Matsuoka, Nikhil C. Munshi, Yu-Tzu Tai, Mehmet K. Samur, Yawara Kawano, Shingo Usuki, Shinjiro Hino, Yong Kim, Virangika K. Wimalasena, Catrine Johansson, Takeshi Masuda, Chengkui Pei, Deyao Li, Xiaofeng Zhang, Keiji Kurata, Daisuke Ogiya, Berkley E. Gryder, Tingjian Wang, Paul M.C. Park, Hiroto Ohguchi
Supplementary Methods, compound synthesis, Supplementary Materials and Supplementary References
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74ff6a7d3836bc266c36040203fb6498
https://doi.org/10.1158/2643-3230.22543987
https://doi.org/10.1158/2643-3230.22543987
Autor:
Jun Qi, A. Thomas Look, Kimberly Stegmaier, Brian J. Abraham, Martha L. Bulyk, Ernst Schönbrunn, John Easton, Olaf Wiest, Taylor R. Quinn, Melissa J. Bikowitz, Antonio R. Perez-Atayde, Amanda L. Robichaud, Amy Saur Conway, Ken Morita, Logan H. Sigua, Paul M.C. Park, Lily Maxham, Maya Mundada, Ying Shao, Anand G. Patel, Stephanie Nance, Noha A.M. Shendy, Luca Mariani, Neekesh V. Dharia, Deyao Li, Mark W. Zimmerman, Virangika K. Wimalasena, Tingjian Wang, Adam D. Durbin
Gene expression is regulated by promoters and enhancers marked by histone H3 lysine 27 acetylation (H3K27ac), which is established by the paralogous histone acetyltransferases (HAT) EP300 and CBP. These enzymes display overlapping regulatory roles in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61071f79f8085d7c8ad075581b3011bc
https://doi.org/10.1158/2159-8290.c.6549578.v1
https://doi.org/10.1158/2159-8290.c.6549578.v1
Autor:
Gagan Dhawan, Jon Erickson, Wei Zhang, Tingjian Wang, Zied Gaieb, Deyao Li, Jun Qi, Shuai Liu, Logan H. Sigua, Hailemichael O. Yosief, Ernst Schönbrunn, Virangika K. Wimalasena, Alex Muthengi, M.J. Bikowitz, Rommie E. Amaro
Publikováno v:
Journal of Medicinal Chemistry. 64:5787-5801
The use of epigenetic bromodomain inhibitors as anticancer therapeutics has transitioned from targeting bromodomain extraterminal domain (BET) proteins into targeting non-BET bromodomains. The two most relevant non-BET bromodomain oncology targets ar
Publikováno v:
Mol Cell
Transcription is epigenetically regulated by the orchestrated function of chromatin-binding proteins that tightly control the expression of master transcription factors, effectors, and supportive housekeeping genes required for establishing and propa
Autor:
S Jimmy Budiardjo, Jacqueline J Stevens, Anna L Calkins, Ayotunde P Ikujuni, Virangika K Wimalasena, Emre Firlar, David A Case, Julie S Biteen, Jason T Kaelber, Joanna SG Slusky
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c352163b4785135bf8649dbb594daedc
https://doi.org/10.7554/elife.73297.sa2
https://doi.org/10.7554/elife.73297.sa2