Predicted structural mimicry of spike receptor-binding motifs from highly pathogenic human coronaviruses

Autor: Christopher A. Beaudoin, Arian R. Jamasb, Ali F. Alsulami, Liviu Copoiu, Andries J. van Tonder, Sharif Hala, Bridget P. Bannerman, Sherine E. Thomas, Sundeep Chaitanya Vedithi, Pedro H.M. Torres, Tom L. Blundell

Publikováno v: Computational and Structural Biotechnology Journal, Vol 19, Iss , Pp 3938-3953 (2021)

Viruses often encode proteins that mimic host proteins in order to facilitate infection. Little work has been done to understand the potential mimicry of the SARS-CoV-2, SARS-CoV, and MERS-CoV spike proteins, particularly the receptor-binding motifs,

Externí odkaz: https://doaj.org/article/fc38282fc8cf4a6ebe271959bab2bffd

Ephrin (Eph) receptor and downstream signaling pathways: a promising potential targeted therapy for COVID‑19 and associated cancers and diseases

Autor: Hamidreza Zalpoor, Abdullatif Akbari, Mohsen Nabi-Afjadi

Publikováno v: Computational and Structural Biotechnology Journal

Graphical abstract
Viruses often encode proteins that mimic host proteins in order to facilitate infection. Little work has been done to understand the potential mimicry of the SARS-CoV-2, SARS-CoV, and MERS-CoV spike proteins, particularly the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::102adc584de595407501d4738588a1c1
https://pubmed.ncbi.nlm.nih.gov/34234921

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The Heterogeneous Landscape and Early Evolution of Pathogen-Associated CpG Dinucleotides in SARS-CoV-2.

Autor: Di Gioacchino A; Laboratoire de Physique de l'Ecole Normale Supérieure, PSL & CNRS UMR8063, Sorbonne Université, Université de Paris, F-75005 Paris, France., Šulc P; School of Molecular Sciences and Center for Molecular Design and Biomimetics, The Biodesign Institute, Arizona State University, 1001 South McAllister Avenue, Tempe, Arizona 85281, USA., Komarova AV; Molecular Genetics of RNA viruses, Department of Virology, Institut Pasteur, CNRS UMR-3569, 75015 Paris, France., Greenbaum BD; Computational Oncology, Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, 1275 York Avenue New York, NY 10065., Monasson R; Laboratoire de Physique de l'Ecole Normale Supérieure, PSL & CNRS UMR8063, Sorbonne Université, Université de Paris, F-75005 Paris, France., Cocco S; Laboratoire de Physique de l'Ecole Normale Supérieure, PSL & CNRS UMR8063, Sorbonne Université, Université de Paris, F-75005 Paris, France.

Publikováno v: SSRN [SSRN] 2020 May 27, pp. 3611280. Date of Electronic Publication: 2020 May 27.