Zobrazeno 1 - 10
of 12 206
pro vyhledávání: '"Viral Entry"'
Autor:
Jiayuan Sun, Yige Ding, Qian Zhou, Peter Kalds, Jianlin Han, Keshan Zhang, Yinghui Wei, Weiwei Wu, Xiaolong Wang, Wenxin Zheng
Publikováno v:
Virology Journal, Vol 21, Iss 1, Pp 1-11 (2024)
Abstract The orf virus (ORFV) poses a serious threat to the health of domestic small ruminants (i.e., sheep and goats) and humans on a global scale, causing around $150 million in annual losses to livestock industry. However, the host factors involve
Externí odkaz:
https://doaj.org/article/9249903b958e4982b4b3a669b7f57bdc
Autor:
Qiaoyun Song, Haoyue Zhu, Manlan Qiu, Jialiao Cai, Yun Hu, Haixia Yang, Shuwen Rao, Yaolan Li, Manmei Li, Lijun Hu, Shuqin Wang, Jian Hong, Wencai Ye, Heru Chen, Ying Wang, Wei Tang
Publikováno v:
mBio, Vol 15, Iss 9 (2024)
ABSTRACT Infection with respiratory syncytial virus (RSV) is a major cause of acute lower respiratory tract disease in young children and older people. Despite intensive efforts over the past few decades, no direct-acting small-molecule agents agains
Externí odkaz:
https://doaj.org/article/6a579b034b354320b9636abfc352a731
Autor:
Yuka Otsuka, Lizhou Zhang, Huihui Mou, Justin Shumate, Claire E. Kitzmiller, Louis Scampavia, Thomas D. Bannister, Michael Farzan, Hyeryun Choe, Timothy P. Spicer
Publikováno v:
SLAS Discovery, Vol 29, Iss 6, Pp 100178- (2024)
Emerging highly pathogenic viruses can pose profound impacts on global health, the economy, and society. To meet that challenge, the National Institute of Allergy and Infectious Diseases (NIAID) established nine Antiviral Drug Discovery (AViDD) cente
Externí odkaz:
https://doaj.org/article/11c7a571d55c43108e85b47fce35be0e
Publikováno v:
Poultry Science, Vol 103, Iss 9, Pp 103944- (2024)
ABSTRACT: Newcastle disease virus, a member of the Paramyxoviridae family, causes significant economic losses in poultry worldwide. To identify novel antiviral agents against NDV, 36 canthin-6-one analogs were evaluated in this study. Our data showed
Externí odkaz:
https://doaj.org/article/53d084f253444fc08352d766a3663aab
Publikováno v:
mBio, Vol 15, Iss 8 (2024)
ABSTRACT Numerous coreceptors have been shown to facilitate hACE2-dependent or hACE2-independent infection by SARS-CoV-2. A recent study published in mBio by Yu et al. showed that the histamine receptor H1 (HRH1) functions as an alternative receptor
Externí odkaz:
https://doaj.org/article/5cb63792fedb4338ae4cf54937cb8151
Autor:
Fei Yu, Xiaoqing Liu, Hailan Ou, Xinyu Li, Ruxin Liu, Xi Lv, Shiqi Xiao, Meilin Hu, Taizhen Liang, Tao Chen, Xuepeng Wei, Zhenglai Zhang, Sen Liu, Han Liu, Yiqiang Zhu, Guangyan Liu, Tianyong Tu, Peiwen Li, Hui Zhang, Ting Pan, Xiancai Ma
Publikováno v:
mBio, Vol 15, Iss 8 (2024)
ABSTRACT Numerous host factors, in addition to human angiotensin-converting enzyme 2 (hACE2), have been identified as coreceptors of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), demonstrating broad viral tropism and diversified drugg
Externí odkaz:
https://doaj.org/article/ce3c48799ab14e25872a6c6f6aabda77
Autor:
Qiaomei Cai, Nina Sun, Yurui Zhang, Jingfeng Wang, Chaohu Pan, Yu Chen, Lili Li, Xiaorong Li, Wancheng Liu, Saba R. Aliyari, Heng Yang, Genhong Cheng
Publikováno v:
Cell & Bioscience, Vol 14, Iss 1, Pp 1-17 (2024)
Abstract Background Viral infection elicits the type I interferon (IFN-I) response in host cells and subsequently inhibits viral infection through inducing hundreds of IFN-stimulated genes (ISGs) that counteract many steps in the virus life cycle. Ho
Externí odkaz:
https://doaj.org/article/abf55842bbbb44ba9ea50a937817633c
Autor:
Yarden Moalem, Rodolfo Katz, Anand G. Subramaniam, Yehonathan Malis, Yakey Yaffe, Nofit Borenstein-Auerbach, Keshet Tadmor, Roey Raved, Ben M. Maoz, Ji Seung Yoo, Yaniv Lustig, Chen Luxenburg, Eran Perlson, Shirit Einav, Ella H. Sklan
Publikováno v:
Emerging Microbes and Infections, Vol 13, Iss 1 (2024)
Sandfly-borne Toscana virus (TOSV) is an enveloped tri-segmented negative single-strand RNA Phlebovirus. It is an emerging virus predominantly endemic in southwestern Europe and Northern Africa. Although TOSV infection is typically asymptomatic or re
Externí odkaz:
https://doaj.org/article/8d335aa4b957434b93d1762152fac7f9
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 14 (2024)
BackgroundAlphaviruses are a diverse group of pathogens that have garnered considerable attention due to their impact on human health. By investigating alphavirus receptors, researchers can elucidate viral entry mechanisms and gain important clues fo
Externí odkaz:
https://doaj.org/article/c1a1dfd6020a40c4927cbd84244fe480
Publikováno v:
Frontiers in Medicine, Vol 11 (2024)
The global pandemic caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has led to an urgent need for effective therapeutic options. SARS-CoV-2 is a novel coronavirus responsible for the COVID-19 pandemic that has resulted in s
Externí odkaz:
https://doaj.org/article/3451506123e6407d9e7316e16e09202d