Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Viral Biology"'
Akademický článek
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Akademický článek
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Autor:
Ziesel, Alison
Motivation: SARS-CoV-2 is the virus responsible for the COVID-19 pandemic that currently impacts our world. SARS-CoV-2 is an enveloped, positive sense single stranded RNA virus and like other RNA viruses is known to form RNA secondary structure in it
Externí odkaz:
http://hdl.handle.net/1828/13868
Publikováno v:
Global Virology III: Virology in the 21st Century
Novel experimental and sequencing techniques have led to an exponential explosion and spiraling of data in viral genomics. To analyse such data, rapidly gain information, and transform this information to knowledge, interdisciplinary approaches invol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmc_________::7a4d1ac5687a6e574562e2df3ec13b8e
http://europepmc.org/articles/PMC7114997
http://europepmc.org/articles/PMC7114997
Akademický článek
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Autor:
Andrea Marzi, Paulina Aleksandrowicz, Thomas Hoenen, Nadine Beimforde, Stephan Becker, Nadine Biedenkopf, Heinz Feldmann, Hans-Joachim Schnittler
Publikováno v:
The Journal of Infectious Diseases. 204:S957-S967
Virus entry into host cells is the first step of infection and a crucial determinant of pathogenicity. Here we show that Ebola virus-like particles (EBOV-VLPs) composed of the glycoprotein GP(1,2) and the matrix protein VP40 use macropinocytosis and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4ff1a35dcbbf78845d02b5882d8709b
https://doi.org/10.1093/infdis/jir326
https://doi.org/10.1093/infdis/jir326
Autor:
Joshua C. Johnson, Nicole Glennon, Lisa E. Hensley, Erol E. Gulcicek, Daisy W. Leung, Lawrence Leung, Reed S. Shabman, Kathryn L. Stone, Gaya K. Amarasinghe, Christopher F. Basler
Publikováno v:
The Journal of Infectious Diseases. 204:S911-S918
The Zaire Ebola virus (EBOV) protein VP35 is multifunctional; it inhibits IFN-α/β production and functions as a cofactor of the viral RNA polymerase. Mass spectrometry identified the double stranded RNA binding protein 76 (DRBP76/NFAR-1/NF90) as a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e879f16a7c0b62a0a4e0718fda662696
https://doi.org/10.1093/infdis/jir343
https://doi.org/10.1093/infdis/jir343
Autor:
Yoshihiro Kawaoka, Tokiko Watanabe, Peter Halfmann, Masayuki Shimojima, Hiroko Kozuka-Hata, Ayaka Iwasa, Shinji Watanabe, Takeshi Noda, Masaaki Oyama
Publikováno v:
The Journal of Infectious Diseases. 204:S919-S926
VP24, the smallest of the 7 structural proteins of Ebola virus (EBOV) [1], is membrane associated [2]. Although the function of VP24 is not fully understood, it is multifunctional, because (1) together with NP and VP35, it is necessary for the format
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e6ef6a59f622270b2868e39a4653061
https://doi.org/10.1093/infdis/jir324
https://doi.org/10.1093/infdis/jir324
Publikováno v:
The Journal of Infectious Diseases. 204:S871-S877
The matrix protein VP40 of Marburg virus promotes the formation and release of virus-like particles (VLPs). Marburg virus VP40 interacts with cellular Tsg101 via its L domain motif; however, mutation of this motif does not affect VLP budding or the a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9088b7338b9f946689a5a1fd1fb20b2e
https://doi.org/10.1093/infdis/jir309
https://doi.org/10.1093/infdis/jir309
Publikováno v:
The Journal of Infectious Diseases. 204:S861-S870
Marburg virus (MARV) and the closely related Ebola virus (EBOV) belong to the filovirus family and cause a severe hemorrhagic fever in humans, with mortality rates up to 90%. Currently, there is no approved vaccine or antiviral treatment. Filoviruses
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c27f0a5c86766c091e59414ea11183e7
https://doi.org/10.1093/infdis/jir308
https://doi.org/10.1093/infdis/jir308