Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Vir B Singh"'
Autor:
Joseph W Jackson, Meera V Singh, Vir B Singh, Letitia D Jones, Gregory A Davidson, Sara Ture, Craig N Morrell, Giovanni Schifitto, Sanjay B Maggirwar
Publikováno v:
PLoS ONE, Vol 11, Iss 6, p e0157115 (2016)
Platelets play an essential role in hemostasis and wound healing by facilitating thrombus formation at sites of injury. Platelets also mediate inflammation and contain several pro-inflammatory molecules including cytokines and chemokines that mediate
Externí odkaz:
https://doaj.org/article/afc10c01c2484776997688e98f8d9a9d
Publikováno v:
Journal of Virus Eradication, Vol 9, Iss 3, Pp 100341- (2023)
Despite more than 20 years of combination antiretroviral therapy (cART), complete eradication of HIV remains a daunting task. While cART has been very effective in limiting new cycles of infection and keeping viral load below detectable levels with p
Externí odkaz:
https://doaj.org/article/5e7821350c1c4f6b8957678d86fb024a
Autor:
Meera V. Singh, Md Nasir Uddin, Vir B. Singh, Angelique N. Peterson, Kyle D. Murray, Yuchuan Zhuang, Alicia Tyrell, Lu Wang, Madalina E. Tivarus, Jianhui Zhong, Xing Qiu, Giovanni Schifitto
Publikováno v:
Frontiers in Neurology, Vol 14 (2023)
IntroductionDue to advances in combined anti-retroviral treatment (cART), there is an increased burden of age-related cerebrovascular disease (CBVD), in people living with HIV (PWH). The underlying CNS injury can be assessed by measuring cerebral blo
Externí odkaz:
https://doaj.org/article/c240987fa02249898f65da6daee56079
Autor:
Emily A. Weber, Meera V. Singh, Vir B. Singh, Joseph W. Jackson, Sara K. Ture, Sumanun Suwunnakorn, Craig N. Morrell, Sanjay B. Maggirwar
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 9, Iss 17 (2020)
Background Microvesicles are cell membrane–derived vesicles that have been shown to augment inflammation. Specifically, monocyte‐derived microvesicles (MDMVs), which can express the coagulation protein tissue factor, contribute to thrombus format
Externí odkaz:
https://doaj.org/article/72cf705b06c24b648bf055402bed22c9
Publikováno v:
Journal of NeuroVirology. 28:305-311
We previously showed that HIV-1 can alter the expression of tight junction proteins by downregulating Sonic hedgehog (Shh) signaling, thereby disrupting blood–brain barrier (BBB) integrity. In this study, we employed a conditional, CNS specific, Ta
Autor:
Emily A. Weber, Sanjay B. Maggirwar, Pawel Kalinski, Vir B. Singh, Meera V. Singh, Sydney Simpson, Sumanun Suwunnakorn
Publikováno v:
J Leukoc Biol
In addition to their role in hemostasis, platelets store numerous immunoregulatory molecules such as CD40L, TGFβ, β2-microglobulin, and IL-1β and release them upon activation. Previous studies indicate that activated platelets form transient compl
Autor:
Meera V. Singh, Sara Ture, Joseph W. Jackson, Craig N. Morrell, Sumanun Suwunnakorn, Vir B. Singh, Emily A. Weber, Sanjay B. Maggirwar
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Microvesicles are cell membrane–derived vesicles that have been shown to augment inflammation. Specifically, monocyte‐derived microvesicles (MDMVs), which can express the coagulation protein tissue factor, contribute to thrombus format
Autor:
Santhi Gorantla, Sanjay B. Maggirwar, Vir B. Singh, Dorota Piekna-Przybylska, Meera V. Singh, Larisa Y. Poluektova
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-8 (2017)
Scientific Reports
Scientific Reports
Infiltration of infected leukocytes culminates in establishment of a brain niche for Human Immunodeficiency Virus (HIV) during acute phase of infection, initiating an ongoing cascade of persistent viral replication and inflammation, that causes irrev
Publikováno v:
Journal of Neurovirology
The neuroteratogenic nature of Zika Virus (ZIKV) infection has converted what would have been a tropical disease into a global threat. Zika is transmitted vertically via infected placental cells especially in the first and second trimesters. In the d
Autor:
James Palis, Vir B. Singh, Meera V. Singh, Sumanun Suwunnakorn, Sanjay B. Maggirwar, Ayse Kizilyer
Publikováno v:
Scientific Reports
Scientific Reports, Vol 9, Iss 1, Pp 1-15 (2019)
Scientific Reports, Vol 9, Iss 1, Pp 1-15 (2019)
Neurotrophin signaling modulates the differentiation and function of mature blood cells. The expression of neurotrophin receptors and ligands by hematopoietic and stromal cells of the bone marrow indicates that neurotrophins have the potential to reg