Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Vipul T. Vachharajani"'
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
The formation of a hollow lumen surrounded by cells is a key developmental process that sets the shape of tissues and organs. Here, the authors show how the combined influence of geometric constraints imposed by cell packing and osmotic pressure can
Externí odkaz:
https://doaj.org/article/114c674fd5ef4820af612699a1723983
Publikováno v:
Cell Reports: Methods, Vol 2, Iss 9, Pp 100278- (2022)
Summary: Numerous proteins experience and respond to mechanical forces as an integral part of their cellular functions, but measuring these forces remains a practical challenge. Here, we present a compact, 11-kDa molecular tension sensor termed STReT
Externí odkaz:
https://doaj.org/article/13e63ac92d9c4dd98aff36435b79d1cd
Autor:
Crystal L. Mackall, Ronald D. Vale, Alexander R. Dunn, Peng Xu, Rachel C. Lynn, Johanna Theruvath, Volker Wiebking, Sang M. Nguyen, Sabine Heitzeneder, Rebecca M. Richards, Aidan M. Tousley, Evan W. Weber, Meena Kadapakkam, June H. Myklebust, Louai Labanieh, Vipul T. Vachharajani, Rui Dong, Elena Sotillo, Skyler P. Rietberg, Robbie G. Majzner
Supplemental Table 1 Supplementary Figures 1-10
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::311f40ebf949712905c9428d4941d39e
https://doi.org/10.1158/2159-8290.22535654.v1
https://doi.org/10.1158/2159-8290.22535654.v1
Autor:
Crystal L. Mackall, Ronald D. Vale, Alexander R. Dunn, Peng Xu, Rachel C. Lynn, Johanna Theruvath, Volker Wiebking, Sang M. Nguyen, Sabine Heitzeneder, Rebecca M. Richards, Aidan M. Tousley, Evan W. Weber, Meena Kadapakkam, June H. Myklebust, Louai Labanieh, Vipul T. Vachharajani, Rui Dong, Elena Sotillo, Skyler P. Rietberg, Robbie G. Majzner
Insufficient reactivity against cells with low antigen density has emerged as an important cause of chimeric antigen receptor (CAR) T-cell resistance. Little is known about factors that modulate the threshold for antigen recognition. We demonstrate t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f70c30aecf09a358b25065ab2c1e623f
https://doi.org/10.1158/2159-8290.c.6547904.v1
https://doi.org/10.1158/2159-8290.c.6547904.v1
Publikováno v:
bioRxiv
Latrophilins are adhesion G-protein coupled receptors (aGPCRs) that control excitatory synapse formation. aGPCRs, including latrophilins, are autoproteolytically cleaved at their GPCR-Autoproteolysis Inducing (GAIN) domain, but the two resulting frag
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::119301dbc6de89cc6c9ef7c3902a4a9c
https://doi.org/10.1101/2023.01.12.523854
https://doi.org/10.1101/2023.01.12.523854
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
Nature Communications
Nature Communications
The formation of a hollow lumen in a formerly solid mass of cells is a key developmental process whose dysregulation leads to diseases of the kidney and other organs. Hydrostatic pressure has been proposed to drive lumen expansion, a view that is sup
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c022384c25dbf23d6c9aafaa37b78807
https://doaj.org/article/114c674fd5ef4820af612699a1723983
https://doaj.org/article/114c674fd5ef4820af612699a1723983
Autor:
Rajarshi P. Ghosh, Lin Ning, Jan Liphardt, Po-Ssu Huang, Muneaki Nakamura, Namrata Anand, Michael Z. Lin, Rui Gong, Sasha Zemsky, Gregory M. Alushin, Robert Chen, Paul V. Ruijgrok, Alexander E. Chu, Zev Bryant, Vipul T. Vachharajani, Raphael R. Eguchi
Publikováno v:
Nature Chemical Biology. 17:540-548
Precision tools for spatiotemporal control of cytoskeletal motor function are needed to dissect fundamental biological processes ranging from intracellular transport to cell migration and division. Direct optical control of motor speed and direction
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ea00fbb3bd62b156dfdf3c2e9d1eafe
https://doi.org/10.1038/s41589-021-00740-7
https://doi.org/10.1038/s41589-021-00740-7
Numerous proteins experience and respond to mechanical forces as an integral part of their cellular functions, but measuring these forces remains a practical challenge. Here, we present a compact, 11 kDa molecular tension sensor termed STReTCh (Sensi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::46423d1b8d4619da24edea482d188f8c
https://doi.org/10.1101/2021.12.31.474658
https://doi.org/10.1101/2021.12.31.474658
Publikováno v:
Biophysical Journal. 122:92a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::27035da823b1264cf07373a82992b533
https://doi.org/10.1016/j.bpj.2022.11.696
https://doi.org/10.1016/j.bpj.2022.11.696
Autor:
Aidan Tousley, Sabine Heitzeneder, Johanna Theruvath, Robbie G. Majzner, Skyler P. Rietberg, Elena Sotillo, Volker Wiebking, Ronald D. Vale, Rui Dong, Rebecca Richards, Peng Xu, Evan W. Weber, Alexander R. Dunn, Rachel C. Lynn, Louai Labanieh, Vipul T. Vachharajani, Sang M. Nguyen, Meena Kadapakkam, Crystal L. Mackall, June Helen Myklebust
Publikováno v:
Cancer Discov
Cancer discovery, vol 10, iss 5
Cancer discovery, vol 10, iss 5
Insufficient reactivity against cells with low antigen density has emerged as an important cause of chimeric antigen receptor (CAR) T-cell resistance. Little is known about factors that modulate the threshold for antigen recognition. We demonstrate t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37be618bc24a6cfd2084ac1ba61efbba
https://europepmc.org/articles/PMC7939454/
https://europepmc.org/articles/PMC7939454/