Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Vipul N, Mankad"'
Autor:
Todd M. Gardner, Donald E. Culberson, Arvind K. Shah, Vipul N. Mankad, Elizabeth A. Manci, Yih-Ming Yang, Randall W. Powell, Johnson Haynes
Publikováno v:
British Journal of Haematology. 123:359-365
More precise analysis of causes of death is needed to focus research efforts and improve morbidity and mortality in sickle cell disease. In this study, the morphological evidence of the cause of death was studied in 306 autopsies of sickle cell disea
Autor:
Vipul N. Mankad
Publikováno v:
Pediatric Pathology & Molecular Medicine. 20:1-13
During the past several decades, our understanding of the complex pathophysiology of vasoocclusion associated with sickle cell disease has improved greatly. Interaction of genes, hemoglobin molecules, red cell membrane and metabolic changes, cell-cel
Autor:
Stephanie K. Shriver, Vipul N. Mankad, R. Blaine Moore, Lucy D. Jenkins, Arvind K. Shah, Gordon Alf Plishker
Publikováno v:
American Journal of Hematology. 56:100-106
We have tested the hypothesis that dense cell formation in sickle cell disease is associated with increased binding of calpromotin to the membrane, an event that occurs during the activation of calcium-dependent potassium transport. By SDS polyacryla
Publikováno v:
American Journal of Hematology. 46:259-263
DNA-synthesis stage and total number of circulating burst-forming-units-erythroid (BFU-E) have been inversely correlated with hemoglobin F levels in the peripheral blood, as well as in the cells from the BFU-E-derived colonies obtained from homozygou
Publikováno v:
Cell Proliferation. 26:519-529
The human erythroleukaemic cell line K562, in response to various chemical agents, undergoes differentiation and exhibits exclusive production of fetal and embryonic haemoglobins. In this study we have compared the efficiency of natural growth factor
Publikováno v:
Journal of Pediatric Surgery. 27:215-219
Acute splenic sequestration crisis (ASSC) in children with various forms of sickle cell disease can result in life-threatening circulatory collapse due to the loss of circulating blood volume. Over a 6-year period we have treated 12 patients ranging
Publikováno v:
Journal of Biological Chemistry. 266:18964-18968
We have demonstrated that calcium-dependent potassium transport in erythrocytes requires the participation of a cytoplasmic protein. Activation of calcium-dependent potassium transport causes an increase in the membrane-bound levels of this protein w
Publikováno v:
Archives of Biochemistry and Biophysics. 278:416-424
The incubation of erythrocyte suspensions or isolated membranes containing a residual amount of hemoglobin (0.04% of original cellular hemoglobin) with tert -butyl hydroperoxide (tBHP, 0.5 m m ) caused significant inhibition of basal and calmodulin-s
Autor:
Arvind K. Shah, Yih-Ming Yang, J. P. Williams, R. B. Moore, Vipul N. Mankad, Elizabeth A. Manci, Harpen, B. G. Brogdon, Gesina L. Longenecker
Publikováno v:
Blood. 75:274-283
A longitudinal, prospective, controlled evaluation of magnetic resonance images (MRI) of long bones in sickle cell patients was undertaken simultaneously with assessment of clinical status and hematologic parameters, including dense erythrocytes. MRI
Autor:
Donald E. Culberson, Julia M. Gardner, J. Elyse Holladay, Randall W. Powell, B. G. Brogdon, Arvind K. Shah, Elizabeth A. Manci, Vipul N. Mankad
Publikováno v:
Archives of pathologylaboratory medicine. 128(6)
Context.—Magnetic resonance imaging of bone marrow in homozygous sickle cell disease (hemoglobin [Hb] SS) shows nonhomogeneous, mottled signals that increase with age and number of crises. The pattern of these signals is reminiscent of the underlyi