Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Vipin T Sreedharan"'
Autor:
Irina Kulemzina, Martin R Schumacher, Vikash Verma, Jochen Reiter, Janina Metzler, Antonio Virgilio Failla, Christa Lanz, Vipin T Sreedharan, Gunnar Rätsch, Dmitri Ivanov
Publikováno v:
PLoS Genetics, Vol 8, Iss 8, p e1002856 (2012)
Cohesin is a protein complex that forms a ring around sister chromatids thus holding them together. The ring is composed of three proteins: Smc1, Smc3 and Scc1. The roles of three additional proteins that associate with the ring, Scc3, Pds5 and Wpl1,
Externí odkaz:
https://doaj.org/article/386e9f6313264fad9da55db833a5b261
Autor:
Bettina Sobottka, Marta Nowak, Anja Laura Frei, Martina Haberecker, Samuel Merki, Mitchell P. Levesque, Reinhard Dummer, Holger Moch, Viktor Hendrik Koelzer, Rudolf Aebersold, Melike Ak, Faisal S. Al-Quaddoomi, Jonas Albinus, Ilaria Alborelli, Sonali Andani, Per-Olof Attinger, Marina Bacac, Daniel Baumhoer, Beatrice Beck-Schimmer, Niko Beerenwinkel, Christian Beisel, Lara Bernasconi, Anne Bertolini, Bernd Bodenmiller, Ximena Bonilla, Ruben Casanova, Stéphane Chevrier, Natalia Chicherova, Maya D'Costa, Esther Danenberg, Natalie Davidson, Monica-Andreea Drăganmoch, Stefanie Engler, Martin Erkens, Katja Eschbach, Cinzia Esposito, André Fedier, Pedro Ferreira, Joanna Ficek, Bruno Frey, Sandra Goetze, Linda Grob, Gabriele Gut, Detlef Günther, Pirmin Haeuptle, Viola Heinzelmann-Schwarz, Sylvia Herter, Rene Holtackers, Tamara Huesser, Anja Irmisch, Francis Jacob, Andrea Jacobs, Tim M. Jaeger, Katharina Jahn, Alva R. James, Philip M. Jermann, André Kahles, Abdullah Kahraman, Werner Kuebler, Jack Kuipers, Christian P. Kunze, Christian Kurzeder, Kjong-Van Lehmann, Sebastian Lugert, Gerd Maass, Markus G. Manz, Philipp Markolin, Julien Mena, Ulrike Menzel, Julian M. Metzler, Nicola Miglino, Emanuela S. Milani, Simone Muenst, Riccardo Murri, Charlotte K.Y. Ng, Stefan Nicolet, Patrick G.A. Pedrioli, Lucas Pelkmans, Salvatore Piscuoglio, Michael Prummer, Mathilde Ritter, Christian Rommel, María L. Rosano-González, Gunnar Rätsch, Natascha Santacroce, Jacobo Sarabia del Castillo, Ramona Schlenker, Petra C. Schwalie, Severin Schwan, Tobias Schär, Gabriela Senti, Franziska Singer, Sujana Sivapatham, Berend Snijder, Vipin T. Sreedharan, Stefan Stark, Daniel J. Stekhoven, Alexandre P.A. Theocharides, Tinu M. Thomas, Markus Tolnay, Vinko Tosevski, Nora C. Toussaint, Mustafa A. Tuncel, Marina Tusup, Audrey Van Drogen, Marcus Vetter, Tatjana Vlajnic, Sandra Weber, Walter P. Weber, Rebekka Wegmann, Michael Weller, Fabian Wendt, Norbert Wey, Andreas Wicki, Mattheus HE Wildschut, Bernd Wollscheid, Shuqing Yu, Johanna Ziegler, Marc Zimmermann, Martin Zoche, Gregor Zuend
Publikováno v:
Laboratory Investigation; a Journal of Technical Methods and Pathology
CD8+ tumor-infiltrating T cells can be regarded as one of the most relevant predictive biomarkers in immune-oncology. Highly infiltrated tumors, referred to as inflamed (clinically “hot”), show the most favorable response to immune checkpoint inh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d74ecfeeb15c1b4897606a94b52a648
Autor:
René Holtackers, Simone Muenst, Martin Zoche, Rudolf Aebersold, Stéphane Chevrier, Tobias Schär, Bettina Sobottka, Marc Zimmermann, Abdullah Kahraman, Lucas Pelkmans, Faisal Alquaddoomi, Philip Jermann, Natascha Santacroce, Andreas Wicki, Norbert Wey, Nora C. Toussaint, Monica-Andreea Drăgan, Mattheus H.E. Wildschut, Ruben Casanova, Shuqing Yu, Markus Tolnay, Marcus Vetter, Mustafa Anil Tuncel, Ximena Bonilla, Stefan Nicolet, Gabriele Gut, Stefan G. Stark, Philipp Markolin, Bruno S. Frey, Ramona Schlenker, Rebekka Wegmann, Walter P. Weber, Lara Bernasconi, Emanuela S. Milani, Viktor H. Koelzer, Christian Rommel, Christian P. Kunze, Sylvia Herter, Cinzia Esposito, Gabriela Senti, Michael Prummer, Katja Eschbach, Bernd Wollscheid, Riccardo Murri, Salvatore Piscuoglio, Mathilde Ritter, Mitchell P. Levesque, Christian Beisel, Tim M. Jaeger, Viola Heinzelmann-Schwarz, Gunnar Rätsch, Severin Schwan, Marina Bacac, Reinhard Dummer, Joanna Ficek, Sandra Goetze, Tatjana Vlajnic, Martin Erkens, Ilaria Alborelli, Ulrike Menzel, Vinko Tosevski, Markus G. Manz, Werner Kuebler, Detlef Günther, Julian M. Metzler, Daniel J. Stekhoven, Christian Kurzeder, Anja Frei, Tamara Huesser, Marta Nowak, Melike Ak, Francis Jacob, Gregor Zuend, Berend Snijder, Martina Haberecker, Pirmin Haeuptle, Anja Irmisch, Maya D'Costa, Linda Grob, Natalia Chicherova, Bernd Bodenmiller, Johanna Ziegler, Per-Olof Attinger, Jack Kuipers, Katharina Jahn, Nicola Miglino, Natalie R. Davidson, Jacobo Sarabia del Castillo, André Fedier, Fabian Wendt, Esther Danenberg, Pedro Ferreira, María Lourdes Rosano-Gonzalez, Sebastian Lugert, Andrea Jacobs, Charlotte K.Y. Ng, Alva Rani James, Tinu M. Thomas, André Kahles, Gerd Maass, Julien Mena, Jonas B. Albinus, Daniel Baumhoer, Sonali Andani, Petra C. Schwalie, Anne Bertolini, Marina Tusup, Franziska Singer, Alexandre Theocharides, Sandra Weber, Beatrice Beck-Schimmer, Sujana Sivapatham, Kjong-Van Lehmann, Stefanie Engler, Holger Moch, Niko Beerenwinkel, Vipin T. Sreedharan, Michael Weller, Audrey Van Drogen, Patrick G. A. Pedrioli
The application and integration of molecular profiling technologies create novel opportunities for personalized medicine. Here, we introduce the Tumor Profiler Study, an observational trial combining a prospective diagnostic approach to assess the re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44d8c3ca713e49a95422d2c3b283d33f
Autor:
Raphael Pelossof, Christof Fellmann, Qing Xiang, Darjus F. Tschaharganeh, Thomas Hoffmann, Vishal Thapar, Christina S. Leslie, Johannes Zuber, Ralph Garippa, Scott W. Lowe, Yuanzhe Guan, Chun-Hao Huang, Gunnar Rätsch, Nishi Sinha, Prem K. Premsrirut, Christian Widmer, Lauren Fairchild, Dan-Yu Lai, Vipin T. Sreedharan
Publikováno v:
Nature biotechnology
We present SplashRNA, a sequential classifier to predict potent microRNA-based short hairpin RNAs (shRNAs). Trained on published and novel data sets, SplashRNA outperforms previous algorithms and reliably predicts the most efficient shRNAs for a give
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::882a7982313d98863f3c1a8eae92ab82
https://doi.org/10.1038/nbt.3807
https://doi.org/10.1038/nbt.3807
Autor:
David Kuo, Philipp Drewe, Theofanis Karaletsos, Gunnar Rätsch, Hans-Guido Wendel, Kamini Singh, Yi Zhong, Vipin T. Sreedharan
Publikováno v:
Bioinformatics
Motivation Deep sequencing based ribosome footprint profiling can provide novel insights into the regulatory mechanisms of protein translation. However, the observed ribosome profile is fundamentally confounded by transcriptional activity. In order t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::038f9463cc9285d2513c1ef555835b5f
https://doi.org/10.1093/bioinformatics/btw585
https://doi.org/10.1093/bioinformatics/btw585
Publikováno v:
Bioinformatics
Motivation: High-throughput sequencing of mRNA (RNA-Seq) has led to tremendous improvements in the detection of expressed genes and reconstruction of RNA transcripts. However, the extensive dynamic range of gene expression, technical limitations and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::daaa1e38b9614b0d1da30f49ced82786
http://europepmc.org/articles/PMC3789545
http://europepmc.org/articles/PMC3789545
Autor:
Georg Zeller, Regina Bohnert, Géraldine Jean, Pramod Kaushik Mudrakarta, Vipin T. Sreedharan, Philipp Drewe, Gunnar Rätsch, Sebastian J. Schultheiss, Nico Görnitz, André Kahles
Publikováno v:
Bioinformatics
Bioinformatics, Oxford University Press (OUP), 2014, epub ahead of print. ⟨10.1093/bioinformatics/btt731⟩
Bioinformatics, Oxford University Press (OUP), 2014, epub ahead of print. ⟨10.1093/bioinformatics/btt731⟩
We present Oqtans, an open-source workbench for quantitative transcriptome analysis, that is integrated in Galaxy. Its distinguishing features include customizable computational workflows and a modular pipeline architecture that facilitates comparati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::027e9ac533f2b45176b486864b8efca8
https://hal.archives-ouvertes.fr/hal-00965351
https://hal.archives-ouvertes.fr/hal-00965351
Autor:
Oliver Stegle, Eric J. Belfield, Vipin T. Sreedharan, Christopher Toomajian, Paul J. Kersey, Sebastian J. Schultheiss, Joshua G. Steffen, André Kahles, Edward J. Osborne, Nicholas P. Harberd, Philipp Drewe, Paula X. Kover, Gunnar Rätsch, Richard M. Clark, Xiangchao Gan, Jonas Behr, Paul S. Derwent, Rune Lyngsoe, Géraldine Jean, Eric Kemen, Regina Bohnert, Richard Mott, Katie L. Hildebrand
Publikováno v:
Nature
Genetic differences between Arabidopsis thaliana accessions underlie the plant's extensive phenotypic variation, and until now these have been interpreted largely in the context of the annotated reference accession Col-0. Here we report the sequencin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16004774665d95abce874809321ffe57
https://hdl.handle.net/11858/00-001M-0000-0013-BA2A-5
https://hdl.handle.net/11858/00-001M-0000-0013-BA2A-5
Autor:
Kathie L. Watkins, Christian Widmer, Vipin T. Sreedharan, Joseph D. Watson, David M. Miller, Rebecca McWhirter, Georg Zeller, Sarah C. Petersen, Gunnar Rätsch, Susan Strome, Jeanyoung Jo, Stefan R. Henz, Stephen E Von Stetina, Lisa N. Petrella, W. Clay Spencer, Menachem Katz, Shai Shaham, Valerie Reinke
Publikováno v:
Genome research. 21(2)
The C. elegans genome has been completely sequenced, and the developmental anatomy of this model organism is described at single-cell resolution. Here we utilize strategies that exploit this precisely defined architecture to link gene expression to c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::916bdf2cf803859aab42086df219c61f
https://pubmed.ncbi.nlm.nih.gov/21177967
https://pubmed.ncbi.nlm.nih.gov/21177967
Publikováno v:
Current Protocols in Bioinformatics
Next-generation sequencing technologies have revolutionized genome and transcriptome sequencing. RNA-Seq experiments are able to generate huge amounts of transcriptome sequence reads at a fraction of the cost of Sanger sequencing. Reads produced by t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f1333b12f622b6867fd05761398c499
https://doi.org/10.1002/0471250953.bi1106s32
https://doi.org/10.1002/0471250953.bi1106s32