Zobrazeno 1 - 10 of 11 pro vyhledávání: '"Viorel Mocanu"'
1
Local budget balance and influence factors
Autor: Svetlana Platagea Gombos, Viorel Mocanu, Bogdan Istrate, Tiberiu Vasile Barladeanu
Publikováno v: Proceedings of the International Conference on Business Excellence. 16:400-408
The local budget appears as the main component of local finances that derives from all public finances and is individualized by a certain structure in which the number of administrative-territorial units in a country, the public services provided, th
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::977f7959522832ee4eced61d8a91a596
https://doi.org/10.2478/picbe-2022-0039
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2
The effects of sustainable economic development on the quality of life in the context of the enlargement of the European Union
Autor: Amelia Diaconu, Viorel Mocanu, Maria Loredana Popescu, Mihai Dinu
Publikováno v: Proceedings of the International Conference on Business Excellence. 16:317-326
The whole historical evolution of economic development, with all its positive valences, but also with its failures, has prepared the conditions for the affirmation and emergence of sustainable development. Sustainable development expresses the need t
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1257907d2715438b1beccc868768fbaf
https://doi.org/10.2478/picbe-2022-0031
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3
Structure-Based Design, Synthesis, and Biochemical and Pharmacological Characterization of Novel Salvinorin A Analogues as Active State Probes of the κ-Opioid Receptor
Autor: Viorel Mocanu, Jordan K. Zjawiony, William C. Wetsel, Philip D. Mosier, Ruslan V. Bikbulatov, Carol E. Parker, Nedyalka Dicheva, Richard B. Westkaemper, Feng Yan, Bryan L. Roth, John A. Allen
Publikováno v: Biochemistry. 48:6898-6908
Salvinorin A, the most potent naturally occurring hallucinogen, has attracted an increasing amount of attention since the kappa-opioid receptor (KOR) was identified as its principal molecular target by us [Roth, B. L., et al. (2002) Proc. Natl. Acad.
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb44d14f93df9d1f6d5a35b5824de658
https://doi.org/10.1021/bi900605n
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4
The RGS protein inhibitor CCG-4986 is a covalent modifier of the RGS4 Gα-interaction face
Autor: Francis S. Willard, Adam J. Kimple, David P. Siderovski, Viorel Mocanu, Christopher A. Johnston, Patrick M. Giguère
Publikováno v: Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics. 1774:1213-1220
Regulator of G-protein signaling (RGS) proteins accelerate GTP hydrolysis by Galpha subunits and are thus crucial to the timing of G protein-coupled receptor (GPCR) signaling. Small molecule inhibition of RGS proteins is an attractive therapeutic app
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e19a67c0d71727c219f35f5d5958f704
https://doi.org/10.1016/j.bbapap.2007.06.002
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5
Redox Regulation of RhoA
Autor: Jongyun Heo, Viorel Mocanu, Sharon L. Campbell, Kimberly W. Raines
Publikováno v: Biochemistry. 45:14481-14489
We have previously shown that redox agents including superoxide anion radical and nitrogen dioxide can react with GXXXXGK(S/T)C motif-containing GTPases (i.e., Rac1, Cdc42, and RhoA) to stimulate guanine nucleotide release. We now show that the react
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18aab0454007916c33c3d4023127f71b
https://doi.org/10.1021/bi0610101
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6
A Novel Proteolytic Processing of Prolysyl Oxidase
Autor: Michitsuna Katafuchi, Yoshiyuki Mochida, Carol E. Parker, Mitsuo Yamauchi, Phimon Atsawasuwan, Kentaro Tokutomi, Viorel Mocanu
Lysyl oxidase (LOX) is an amine oxidase that is critical for the stability of connective tissues. The secreted proLOX is enzymatically quiescent and is activated through proteolytic cleavage between residues Gly(162) and Asp(163) (residue numbers acc
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85cc6af822443aac78ded3426c1f7b36
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9
Electrospray ionization tandem mass spectrometry of model peptides reveals diagnostic fragment ions for protein ubiquitination
Autor: Christoph H. Borchers, David G. Klapper, Carol E. Parker, Viorel Mocanu, Maria R. Esteban Warren
Publikováno v: Rapid communications in mass spectrometry : RCM. 19(4)
In this work, synthetic peptides were used to determine the fragmentation behavior of ubiquitinated peptides and to find ions diagnostic for peptide ubiquitination. The ubiquitin-calmodulin peptide1 was chosen as the model peptide for naturally occur
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f10680bbb22d2783c175ea27d36bedd
https://pubmed.ncbi.nlm.nih.gov/15655800
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10
Mechanism of free radical nitric oxide-mediated Ras guanine nucleotide dissociation
Autor: Kirk C. Prutzman, Sharon L. Campbell, Jongyun Heo, Viorel Mocanu
Publikováno v: Journal of molecular biology. 346(5)
Ras proteins cycle between GDP-bound and GTP-bound states to modulate a diverse array of cellular growth processes. In this study, we have elucidated a mechanism by which nitric oxide, in the presence of oxygen (NO/O 2 ), regulates Ras activity. We s
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fd27395021bb058bd7e7d47b6f899d9
https://pubmed.ncbi.nlm.nih.gov/15713491
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